Objective This project aims at demonstrating the feasibility of a non-invasive, safe and patient-friendly methodology for on-site rapid diagnosis of tropical diseases. The proposed approach is based on breath samples analyses, which are easy to obtain and present no discomfort or risk for patients health. In this study will be enrolled patients with three different types of neglected tropical diseases (Hydatidosis, Leishmaniasis and Dengue) from different geographical locations (Europe, South America and Maghreb). Breath sampling will follow a standardised procedure. Analytical chemistry methods will be employed for the identification of the breath volatile biomarkers of these diseases. A pool of potential nanomaterials with high affinity towards the identified VOCs will be selected (e.g. gold nanoparticles, carbon nanotubes and semiconducting nanowires, either pristine or functionalised with selected hydrophobic organic molecules and/or bio-molecules). For maximising the possibility of success of our methodology, we will investigate the synergic effect of different advanced and complementary chemical sensing techniques: Mid-Infrared Quantum Cascade Laser spectroscopy and different types of Chemical Gas Sensors devices. These techniques are particularly attractive, since they can be miniaturised and are suitable for building on-site portable systems. Advanced pattern recognition algorithms will be employed for building discriminative models for the identification of the fingerprints of the different tropical diseases studied, and multisensors data fusion will be then applied for obtaining enhanced resulyts. A point of care prototype will be proposed on the basis of the results obtained and validated on-site. Fields of science medical and health scienceshealth sciencestropical medicinenatural sciencescomputer and information sciencesartificial intelligencepattern recognition Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Topic(s) MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Call for proposal H2020-MSCA-RISE-2014 See other projects for this call Funding Scheme MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinator UPPSALA UNIVERSITET Net EU contribution € 18 000,00 Address VON KRAEMERS ALLE 4 751 05 Uppsala Sweden See on map Region Östra Sverige Östra Mellansverige Uppsala län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 18 000,00 Participants (10) Sort alphabetically Sort by Net EU contribution Expand all Collapse all TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY Participation ended Israel Net EU contribution € 4 500,00 Address SENATE BUILDING TECHNION CITY 32000 Haifa See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 4 500,00 INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU METALE NEFEROASE SIRARE-IMNR Romania Net EU contribution € 184 500,00 Address BULEVARDUL BIRUINTEI 102 077145 Pantelimon Ilfov See on map Region Macroregiunea Trei Bucureşti-Ilfov Ilfov Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 184 500,00 POLITECHNIKA GDANSKA Poland Net EU contribution € 126 000,00 Address UL. G NARUTOWICZA 11/12 80-233 GDANSK See on map Region Makroregion północny Pomorskie Trójmiejski Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 126 000,00 UNIVERSITAET ULM Germany Net EU contribution € 198 000,00 Address HELMHOLTZSTRASSE 16 89081 Ulm See on map Region Baden-Württemberg Tübingen Ulm, Stadtkreis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 198 000,00 MOLECULAR FINGERPRINT SWEDEN AB Sweden Net EU contribution € 67 500,00 Address EKSATRAVAGEN 130 756 55 Uppsala See on map Region Östra Sverige Östra Mellansverige Uppsala län Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 67 500,00 SITEX 45 SRL Romania Net EU contribution € 202 500,00 Address GHICA TEI BLVD,BL.40,AP.2 DEPT.2 114 023709 Bucharest See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Macroregiunea Trei Bucureşti-Ilfov Bucureşti Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 202 500,00 JLM INNOVATION GMBH Germany Net EU contribution € 121 500,00 Address BEETHOVENWEG 41 72076 Tuebingen See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Baden-Württemberg Tübingen Tübingen, Landkreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 121 500,00 UNIWERSYTECKIE CENTRUM MEDYCYNY MORSKIEJ I TROPIKALNEJ Poland Net EU contribution € 63 000,00 Address UL POWSTANIA STYCZNIOWEGO 9 B 81519 GDYNIA See on map Region Makroregion północny Pomorskie Trójmiejski Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 63 000,00 UNIVERSITAT ROVIRA I VIRGILI Spain Net EU contribution € 315 000,00 Address CARRER DE ESCORXADOR 43003 Tarragona See on map Region Este Cataluña Tarragona Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 315 000,00 INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI Romania Net EU contribution € 85 500,00 Address Aleea Grigore Ghica Voda 41A 700487 Iasi See on map Region Macroregiunea Doi Nord-Est Iaşi Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 85 500,00 Partners (3) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. INSTITUT PASTEUR DE TUNIS Tunisia Net EU contribution € 0,00 Address Place Pasteur 13 1002 Tunis See on map Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 243 000,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSITE MOULAY ISMAIL Morocco Net EU contribution € 0,00 Address MARJANE II 50 000 Meknes See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 189 000,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSIDAD DE PAMPLONA Colombia Net EU contribution € 0,00 Address CIUDAD UNIVERSITARIA KM 1 VIA BUCARAMANGA Pamplona See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 225 000,00