Development of a non-invassive breath test for early diagnosis of tropical diseases

Resultado final

Project website creation and updating

Volunteers selection, clinical evaluations and breath sampling

Publications and other dissemination of the results

- Results publication in international journals, conferences and workshops - Results dissemination in different mass-media (radio, TV, journals, You Tube, etc) - Results presentation at specialised fairs (SITEX, MolFing, JLM)

Fabrication of the nanomaterial-based devices

Nanomaterials fabrication and characterisation Nanotechnology-based devices fabrication and characterisation

Material related with formation/training and knowledge-share activities

- Lectures presented by staff members at congresses/conferences organized periodically by different project partners - Workshops for discussing project achievements - Summer/winter training courses on different subjects related with the Project - Seminars presented by seconded staff at host partners

Publicaciones

Exhaled breath analysis for gastric cancer diagnosis in Colombian patients

Autores: Cristhian Manuel Durán-Acevedo, Aylen Lisset Jaimes-Mogollón, Oscar Eduardo Gualdrón-Guerrero, Tesfalem Geremariam Welearegay, Julián Davíd Martinez-Marín, Juan Martín Caceres-Tarazona, Zayda Constanza Sánchez-Acevedo, Kelvin de Jesus Beleño-Saenz, Umut Cindemir, Lars Österlund, Radu Ionescu
Publicado en: Oncotarget, Edición 9/48, 2018, Página(s) 28805-28817, ISSN 1949-2553
Editor: Impact Journals
DOI: 10.18632/oncotarget.25331

Fluctuation-enhanced sensing with organically functionalized gold nanoparticle gas sensors targeting biomedical applications

Autores: Łukasz Lentka, Mateusz Kotarski, Janusz Smulko, Umut Cindemir, Zareh Topalian, Claes G. Granqvist, Raul Calavia, Radu Ionescu
Publicado en: Talanta, Edición 160, 2016, Página(s) 9-14, ISSN 0039-9140
Editor: Elsevier BV
DOI: 10.1016/j.talanta.2016.06.063

Fluctuation-enhanced and conductometric gas sensing with nanocrystalline NiO thin films: A comparison

Autores: Umut Cindemir, Maciej Trawka, Janusz Smulko, Claes-Göran Granqvist, Lars Österlund, Gunnar A. Niklasson
Publicado en: Sensors and Actuators B: Chemical, Edición 242, 2017, Página(s) 132-139, ISSN 0925-4005
Editor: Elsevier BV
DOI: 10.1016/j.snb.2016.11.015

Development and characterization of an electrochemical biosensor for creatinine detection in human urine based on functional molecularly imprinted polymer

Autores: A. Diouf, S. Motia, N. El Alami El Hassani, N. El Bari, B. Bouchikhi
Publicado en: Journal of Electroanalytical Chemistry, Edición 788, 2017, Página(s) 44-53, ISSN 1572-6657
Editor: Elsevier BV
DOI: 10.1016/j.jelechem.2017.01.068

Voltammetric electronic tongue combined with chemometric techniques for direct identification of creatinine level in human urine

Autores: Tarik Saidi, Mohammed Moufid, Omar Zaim, Nezha El Bari, Benachir Bouchikhi
Publicado en: Measurement, Edición 115, 2018, Página(s) 178-184, ISSN 0263-2241
Editor: Elsevier BV
DOI: 10.1016/j.measurement.2017.10.044

Exhaled breath analysis using electronic nose and gas chromatography–mass spectrometry for non-invasive diagnosis of chronic kidney disease, diabetes mellitus and healthy subjects

Autores: Tarik Saidi, Omar Zaim, Mohammed Moufid, Nezha El Bari, Radu Ionescu, Benachir Bouchikhi
Publicado en: Sensors and Actuators B: Chemical, Edición 257, 2018, Página(s) 178-188, ISSN 0925-4005
Editor: Elsevier BV
DOI: 10.1016/j.snb.2017.10.178

Fabrication and characterisation of ligand-functionalised ultrapure monodispersed metal nanoparticle nanoassemblies employing advanced gas deposition technique

Autores: Tesfalem Geremariam Welearegay, Umut Cindemir, Lars Österlund, Radu Ionescu
Publicado en: Nanotechnology, Edición 29/6, 2018, Página(s) 065603, ISSN 0957-4484
Editor: Institute of Physics Publishing
DOI: 10.1088/1361-6528/aa9f65

Electrochemical detection of influenza virus H9N2 based on both immunomagnetic extraction and gold catalysis using an immobilization-free screen printed carbon microelectrode

Autores: Maher Sayhi, Oussama Ouerghi, Kamel Belgacem, Marwa Arbi, Yudum Tepeli, Abdeljalil Ghram, Ülkü Anik, Lars Österlund, Dhafer Laouini, Mohamed Fethi Diouani
Publicado en: Biosensors and Bioelectronics, Edición 107, 2018, Página(s) 170-177, ISSN 0956-5663
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2018.02.018

Exhaled breath gas sensing using pristine and functionalized WO3 nanowire sensors enhanced by UV-light irradiation

Autores: Tarik Saidi, Dariusz Palmowski, Sylwia Babicz-Kiewlicz, Tesfalem Geremariam Welearegay, Nezha El Bari, Radu Ionescu, Janusz Smulko, Benachir Bouchikhi
Publicado en: Sensors and Actuators B: Chemical, Edición 273, 2018, Página(s) 1719-1729, ISSN 0925-4005
Editor: Elsevier BV
DOI: 10.1016/j.snb.2018.07.098

Diagnosis of Human Echinococcosis via Exhaled Breath Analysis: A Promise for Rapid Diagnosis of Infectious Diseases Caused by Helminths

Autores: Tesfalem Geremariam Welearegay, Mohamed Fethi Diouani, Lars Österlund, Sebastian Borys, Samira Khaled, Hanen Smadhi, Florina Ionescu, Meriam Bouchekoua, Dorsaf Aloui, Dhafer Laouini, Umut Cindemir, Radu Ionescu
Publicado en: The Journal of Infectious Diseases, Edición 219, 2018, Página(s) 101-109, ISSN 0022-1899
Editor: University of Chicago Press
DOI: 10.1093/infdis/jiy449

Non-Gaussian Resistance Fluctuations in Gold-Nanoparticle-Based Gas Sensors: An Appraisal of Different Evaluation Techniques

Autores: Łukasz Lentka, Janusz Smulko, Mateusz Kotarski, Claes-Göran Granqvist, Radu Ionescu
Publicado en: Sensors, Edición 17/4, 2017, Página(s) 757, ISSN 1424-8220
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s17040757

Application of Statistical Features and Multilayer Neural Network for Automatic Diagnosis of Arrhythmia by ECG Signals

Autores: A. Ben Slama, L. Lentka, A. Mouelhi, M.F. Diouani, M. Sayadi, J. Smulko
Publicado en: Metrology and Measurement Systems, Edición 25, 2018, Página(s) 87-101, ISSN 0860-8229
Editor: Polish Academy of Sciences
DOI: 10.24425/118163

Mid-infrared thin-film diamond waveguides combined with tunable quantum cascade lasers for analyzing the secondary structure of proteins

Autores: Ángela I. López-Lorente, Pei Wang, Markus Sieger, Ernesto Vargas Catalan, Mikael Karlsson, Fredrik Nikolajeff, Lars Österlund, Boris Mizaikoff
Publicado en: physica status solidi (a), Edición 213/8, 2016, Página(s) 2117-2123, ISSN 1862-6300
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/pssa.201600134

Fluctuation enhanced gas sensing with WO3-based nanoparticle gas sensors modulated by UV light at selected wavelengths

Autores: Maciej Trawka, Janusz Smulko, Lech Hasse, Claes-Göran Granqvist, Fatima Ezahra Annanouch, Radu Ionescu
Publicado en: Sensors and Actuators B: Chemical, Edición 234, 2016, Página(s) 453-461, ISSN 0925-4005
Editor: Elsevier BV
DOI: 10.1016/j.snb.2016.05.032

Printing Ultrasensitive Artificially Intelligent Sensors Array with a Single Self-Propelled Droplet Containing Nanoparticles

Autores: Ekhlas Homede, Mohammad Abo-Jabal, Radu Ionescu, Hossam Haick
Publicado en: Advanced Functional Materials, Edición 26/35, 2016, Página(s) 6359-6370, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201602326

Online monitoring of carbon dioxide and oxygen in exhaled mouse breath via substrate-integrated hollow waveguide Fourier-transform infrared-luminescence spectroscopy

Autores: Felicia Seichter, Erhan Tütüncü, Leila Tamina Hagemann, Josef Vogt, Ulrich Wachter, Michael Gröger, Sandra Kress, Peter Radermacher, Boris Mizaikoff
Publicado en: Journal of Breath Research, Edición 12/3, 2018, Página(s) 036018, ISSN 1752-7163
Editor: Institute of Physics Publishing
DOI: 10.1088/1752-7163/aabf98

Ligand-Capped Ultrapure Metal Nanoparticle Sensors for the Detection of Cutaneous Leishmaniasis Disease in Exhaled Breath

Autores: Tesfalem Geremariam Welearegay, Mohamed Fethi Diouani, Lars Österlund, Florina Ionescu, Kamel Belgacem, Hanen Smadhi, Samira Khaled, Abdelhamid Kidar, Umut Cindemir, Dhafer Laouini, Radu Ionescu
Publicado en: ACS Sensors, Edición 3/12, 2018, Página(s) 2532-2540, ISSN 2379-3694
Editor: american chemical society publications
DOI: 10.1021/acssensors.8b00759

Development of a highly sensitive and selective molecularly imprinted electrochemical sensor for sulfaguanidine detection in honey samples

Autores: Nadia El Alami El Hassani, Eduard Llobet, Laura-Madalina Popescu, Mihai Ghita, Benachir Bouchikhi, Nezha El Bari
Publicado en: Journal of Electroanalytical Chemistry, Edición 823, 2018, Página(s) 647-655, ISSN 1572-6657
Editor: Elsevier BV
DOI: 10.1016/j.jelechem.2018.07.011

Development of a novel electrochemical sensor based on electropolymerized molecularly imprinted polymer for selective detection of sodium lauryl sulfate in environmental waters and cosmetic products

Autores: Soukaina Motia, Ioan Albert Tudor, L. Madalina Popescu, Roxana Mioara Piticescu, Benachir Bouchikhi, Nezha El Bari
Publicado en: Journal of Electroanalytical Chemistry, Edición 823, 2018, Página(s) 553-562, ISSN 1572-6657
Editor: Elsevier BV
DOI: 10.1016/j.jelechem.2018.03.069

A nonenzymatic electrochemical glucose sensor based on molecularly imprinted polymer and its application in measuring saliva glucose

Autores: Alassane Diouf, Benachir Bouchikhi, Nezha El Bari
Publicado en: Materials Science and Engineering: C, Edición 98, 2019, Página(s) 1196-1209, ISSN 0928-4931
Editor: Elsevier BV
DOI: 10.1016/j.msec.2019.01.001

Portable exhaled breath analyzer employing fluctuation-enhanced gas sensing method in resistive gas sensors

Autores: A. Kwiatkowski, T. Chludziński, J. Smulko
Publicado en: Metrology and Measurement Systems, Edición 25, 2018, Página(s) 551–560, ISSN 0860-8229
Editor: Polish Academy of Sciences
DOI: 10.24425/123892

Polycrystalline Diamond Thin-Film Waveguides for Mid-Infrared Evanescent Field Sensors

Autores: Julian Haas, Ernesto Vargas Catalán, Pierre Piron, Fredrik Nikolajeff, Lars Österlund, Mikael Karlsson, Boris Mizaikoff
Publicado en: ACS Omega, Edición 3/6, 2018, Página(s) 6190-6198, ISSN 2470-1343
Editor: American Chemical Society
DOI: 10.1021/acsomega.8b00623

Advanced Photonic Sensors Based on Interband Cascade Lasers for Real-Time Mouse Breath Analysis

Autores: Erhan Tütüncü, Markus Nägele, Steffen Becker, Marc Fischer, Johannes Koeth, Christian Wolf, Stefan Köstler, Volker Ribitsch, Andrea Teuber, Michael Gröger, Sandra Kress, Martin Wepler, Ulrich Wachter, Josef Vogt, Peter Radermacher, Boris Mizaikoff
Publicado en: ACS Sensors, Edición 3/9, 2018, Página(s) 1743-1749, ISSN 2379-3694
Editor: American Chemical Society
DOI: 10.1021/acssensors.8b00477

Infrared spectroscopy based on broadly tunable quantum cascade lasers and polycrystalline diamond waveguides

Autores: Julian Haas, Ernesto Vargas Catalán, Pierre Piron, Mikael Karlsson, Boris Mizaikoff
Publicado en: The Analyst, Edición 143/21, 2018, Página(s) 5112-5119, ISSN 0003-2654
Editor: Royal Society of Chemistry
DOI: 10.1039/c8an00919h

Cascade laser sensing concepts for advanced breath diagnostics

Autores: Erhan Tütüncü, Boris Mizaikoff
Publicado en: Analytical and Bioanalytical Chemistry, 2018, Página(s) 1-8, ISSN 1618-2642
Editor: Springer Verlag
DOI: 10.1007/s00216-018-1509-5

Towards enhanced optical sensor performance: SEIRA and SERS with plasmonic nanostars

Autores: O. Bibikova, J. Haas, A. I. López-Lorente, A. Popov, M. Kinnunen, I. Meglinski, B. Mizaikoff
Publicado en: The Analyst, Edición 142/6, 2017, Página(s) 951-958, ISSN 0003-2654
Editor: Royal Society of Chemistry
DOI: 10.1039/C6AN02596J

Nanocrystalline diamond sensor targeted for selective CRP detection: an ATR-FTIR spectroscopy study

Autores: Per Ola Andersson, Pernilla Viberg, Pontus Forsberg, Fredrik Nikolajeff, Lars Österlund, Mikael Karlsson
Publicado en: Analytical and Bioanalytical Chemistry, Edición 408/14, 2016, Página(s) 3675-3680, ISSN 1618-2642
Editor: Springer Verlag
DOI: 10.1007/s00216-016-9485-0

Towards label-free mid-infrared protein assays: in-situ formation of bare gold nanoparticles for surface enhanced infrared absorption spectroscopy of bovine serum albumin

Autores: Ángela Inmaculada López-Lorente, Pei Wang, Boris Mizaikoff
Publicado en: Microchimica Acta, Edición 184/2, 2017, Página(s) 453-462, ISSN 0026-3672
Editor: Springer Verlag
DOI: 10.1007/s00604-016-2031-0

Detection of ESAT-6 by a label free miniature immuno-electrochemical biosensor as a diagnostic tool for tuberculosis

Autores: Mohamed Fethi Diouani, Oussama Ouerghi, Amira Refai, Kamel Belgacem, Chaker Tlili, Dhafer Laouini, Makram Essafi
Publicado en: Materials Science and Engineering: C, Edición 74, 2017, Página(s) 465-470, ISSN 0928-4931
Editor: Elsevier BV
DOI: 10.1016/j.msec.2016.12.051

Boron-doped diamond modified with gold nanoparticles for the characterization of bovine serum albumin protein

Autores: Ángela I. López-Lorente, Javier Izquierdo, Christine Kranz, Boris Mizaikoff
Publicado en: Vibrational Spectroscopy, Edición 91, 2016, Página(s) 147-156, ISSN 0924-2031
Editor: Elsevier BV
DOI: 10.1016/j.vibspec.2016.10.010

Artificial Sensory Systems Combined with UV-Vis Spectrophotometry as a Robust Approach for VOCs Analysis of Human Urine and Exhaled Breath

Autores: Tarik Saidi, Mohamed Moufid, Omar Zaim, Nezha El Bari, Radu Ionescu, Benachir Bouchikhi
Publicado en: Procedia Technology, Edición 27, 2017, Página(s) 256-257, ISSN 2212-0173
Editor: Elsevier B.V.
DOI: 10.1016/j.protcy.2017.04.110

A Novel Modular eNose System Based on Commercial MOX Sensors to Detect Low Concentrations of VOCs for Breath Gas Analysis

Autores: Carsten Jaeschke, Oriol Gonzalez, Johannes J. Glöckler, Leila T. Hagemann, Kaylen E. Richardson, Francesc Adrover, Marta Padilla, Jan Mitrovics, Boris Mizaikoff
Publicado en: Proceedings, Edición 2/13, 2018, Página(s) 993, ISSN 2504-3900
Editor: MDPI
DOI: 10.3390/proceedings2130993

Ultrapure Organically Modified Gold Nanoparticles for Breath Analysis

Autores: T.G. Welearegay, O.E. Gualdrón, A.L. Jaimes, J.M. Cáceres, G. Pugliese, U. Cindemir, C.M. Durán, L. Österlund, R. Ionescu
Publicado en: Procedia Engineering, Edición 168, 2016, Página(s) 133-136, ISSN 1877-7058
Editor: Elsevier BV
DOI: 10.1016/j.proeng.2016.11.176

Stomach Cancer Detection through Exhaled Breath using Biomarkers Analysis

Autores: A.L. Jaimes, C.M. Durán, O.E. Gualdrón, S.R. Ionescu
Publicado en: Chemical Engineering Transactions, Edición 68, 2018, Página(s) 43-48, ISSN 2283-9216
Editor: Italian Association of Chemical Engineering
DOI: 10.3303/cet1868008

Wireless Electronic Smell System for the Detection of Diseases Through the Exhaled Breath

Autores: C. Cuastumal Vasquez, C. Duran Acevedo
Publicado en: Chemical Engineering Transactions, Edición 68, 2018, Página(s) 391-396
Editor: Italian Association of Chemical Engineering
DOI: 10.3303/cet1868066

Thermal Desorption System for Breath Samples Analysis from Colombian Patients with Gastric Cancer

Autores: J.M. Cáceres, C.M. Durán, O.E. Gualdron
Publicado en: Chemical Engineering Transactions, Edición 68, 2018, Página(s) 427-432, ISSN 2283-9216
Editor: Italian Association of Chemical Engineering
DOI: 10.3303/cet1868072

Detection of seasonal allergic rhinitis from exhaled breath VOCs using an electronic nose based on an array of chemical sensors

Autores: T. Saidi, K. Tahri, N. El Bari, R. Ionescu, B. Bouchikhi
Publicado en: 2015 IEEE SENSORS, 2015, Página(s) 1-4, ISBN 978-1-4799-8203-5
Editor: IEEE
DOI: 10.1109/icsens.2015.7370579

Artificial olfactory systems can detect unique odorant signature of cancerous volatile compounds

Autores: R. Ionescu
Publicado en: Volatiles Metabolomics Analysis in Biomedical Diagnosis Applications, 2018, Página(s) 79-103, ISBN 9781-771887441
Editor: Apple Academic Press

Diamond Waveguides for Infrared Spectroscopy and Sensing

Autores: Á.I. López-Lorente, M. Karlsson, L. Österlund, B. Mizaikoff
Publicado en: Springer Series on Chemical Sensors and Biosensors (Methods and Applications), 2017
Editor: Springer

Derechos de propiedad intelectual

Dispositivo de olfato electrónico para el diagnóstico precoz de cáncer gástrico

Número de solicitud/publicación: NC 2017/0001745
Fecha: 2017-02-23
Solicitante(s): UNIVERSITAT ROVIRA I VIRGILI

The innovative Integration concept by OEM solutions for portable analytical instrumentation of breath analysis

Número de solicitud/publicación: OSIM a16/23450
Fecha: 2018-02-15
Solicitante(s): SITEX 45 SRL

Método para el diagnóstico del Dengue

Número de solicitud/publicación: NC 2018/0004119
Fecha: 2018-10-26
Solicitante(s): UNIVERSITAT ROVIRA I VIRGILI

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Resultado final

Publicaciones

Derechos de propiedad intelectual

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