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Large scale micro-and nanofabrication technologies for bioanalytical devices based on R2R imprinting

Objective

Roll-to-roll (R2R) technologies are mature core processes in manufacturing lines for graphical printing industry. In several other areas (e.g. electronics or optics) R2R techniques are emerging, being expected to notably lower the unit prices of flexible devices.

In particular, recently developed roller-based nanoimprinting methods enable unrivalled throughput and productivity for precise fabrication of micro- and nanoscale patterns.
Areas that will benefit strongly from adopting such R2R nanoimprinting technologies are microfluidics and lab-on-chip products for diagnostics, drug discovery and food control. Such devices require combined printing of micro- and nanostructures and large quantities at low unit costs.

The project R2R Biofluidics aims on the development of a complete process chain for first-time realization of production lines for two selected bioanalytical lab-on-chip devices based on high-throughput R2R nanoimprinting in combination with complementary printing and manufacturing technologies.

Two types of demonstrators will be fabricated targeting application areas, which would clearly benefit from technology advancement in high volume manufacturing, show large potential for commercial exploitation and adopt current standard formats (microtiter plate and microscope slides).

Demonstrator 1 will represent an in-vitro diagnostic (IVD) chip suitable for point-of-care applications, showing improved sensitivity thanks to imprinted nanoscale optical structures and microfluidic channels. R2R fabrication will further greatly reduce production costs and increase manufacturing capacity with respect to currently used products.

Demonstrator 2 will provide a device for improved neuron based high-throughput screening assays in drug development. It will consist of nano– to microstructured, interconnected channels in combination with dedicated biofunctionalized surfaces for alignment and controlled growth of neurons.

Call for proposal

H2020-NMP-2014-2015

See other projects for this call

Sub call

H2020-NMP-PILOTS-2014

Coordinator

JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH
Net EU contribution
€ 2 395 932,91
Address
Leonhardstrasse 59
8010 Graz
Austria

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Region
Südösterreich Steiermark Graz
Activity type
Research Organisations
Other funding
€ 0,00

Participants (11)

BIFLOW SYSTEMS GMBH
Germany
Net EU contribution
€ 247 725,00
Address
Technologie-campus 1
09126 Chemnitz

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Sachsen Chemnitz Chemnitz
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 106 167,86
BIONANONET FORSCHUNGSGESELLSCHAFT MBH
Austria
Net EU contribution
€ 419 779,15
Address
Kaiser-josef-platz 9
8010 Graz

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Region
Südösterreich Steiermark Graz
Activity type
Research Organisations
Other funding
€ 0,00
BIONIC SURFACE TECHNOLOGIES GMBH
Austria
Net EU contribution
€ 225 050,00
Address
Liebenauer Hauptstrasse 2-6
8041 Graz

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Südösterreich Steiermark Graz
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 96 450,00
EV GROUP E. THALLNER GMBH
Austria
Net EU contribution
€ 374 268,13
Address
Di Erich Thallner Strasse 1
4782 St Florian Am Inn

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Region
Westösterreich Oberösterreich Innviertel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 160 400,62
GREINER BIO-ONE DIAGNOSTICS GMBH

Participation ended

Austria
Net EU contribution
€ 26 434,07
Address
Gewerbepark 2
4261 Rainbach Im Muhlkreis
Region
Westösterreich Oberösterreich Mühlviertel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 11 328,89
INMOLD AS
Denmark
Net EU contribution
€ 648 579,16
Address
Savsvinget 4
2970 Horsholm

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Danmark Hovedstaden Nordsjælland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 277 962,50
Innovative Technologies in Biological Systems
Spain
Net EU contribution
€ 295 515,50
Address
Parque Tecnologico De Bizkaia 502-1
48160 Derio

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Noreste País Vasco Bizkaia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 126 649,50
MICRO RESIST TECHNOLOGY GESELLSCHAFT FUER CHEMISCHE MATERIALIEN SPEZIELLER PHOTORESISTSYSTEME MBH
Germany
Net EU contribution
€ 557 375,00
Address
Koepenicker Strasse 325
12555 Berlin

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Berlin Berlin Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 238 875,00
FUNDACION TECNALIA RESEARCH & INNOVATION
Spain
Net EU contribution
€ 675 563,06
Address
Parque Cientifico Y Tecnologico De Bizkaia Astondo Bidea Edificio 700
48160 Derio (Bizkaia)

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Region
Noreste País Vasco Bizkaia
Activity type
Research Organisations
Other funding
€ 0,00
GENSPEED BIOTECH GMBH
Austria
Net EU contribution
€ 357 897,46
Address
Gewerbepark 2
4261 Rainbach Im Muhlkreis

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Westösterreich Oberösterreich Mühlviertel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 153 384,63
SCIENION AG
Germany
Net EU contribution
€ 197 553,13
Address
Otto Hahn Strasse 15
44227 Dortmund

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 84 665,62