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Formation and Characterization of Protein Post-Translational Modifications and Assessment of Cellular Responses by Application of Metals in Biological Systems


Elucidating the cellular response of silver nanoparticles as a potential combinatorial agent for cisplatin chemotherapy

Author(s): Renata Rank Miranda, Micaella Pereira da Fonseca, Barbara Korzeniowska, Lilian Skytte, Kaare Lund Rasmussen, Frank Kjeldsen
Published in: Journal of Nanobiotechnology, Issue 18/1, 2020, ISSN 1477-3155
Publisher: BioMed Central
DOI: 10.1186/s12951-020-00719-x

Cardiomyocyte Proteome Remodeling due to Isoproterenol‐Induced Cardiac Hypertrophy during the Compensated Phase

Author(s): Ricardo Cambraia Parreira, Diana Paola Gómez‐Mendoza, Itamar Couto Guedes Jesus, Rafael Pereira Lemos, Anderson Kennedy Santos, Cristiana Perdigão Rezende, Henrique César Pereira Figueiredo, Mauro Cunha Xavier Pinto, Frank Kjeldsen, Silvia Guatimosim, Rodrigo Ribeiro Resende, Thiago Verano‐Braga
Published in: PROTEOMICS – Clinical Applications, Issue 14/4, 2020, Page(s) 2000017, ISSN 1862-8346
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/prca.202000017

PhosphoShield: Improving Trypsin Digestion of Phosphoproteins by Shielding the Negatively Charged Phosphate Moiety

Author(s): Julia A. Bubis, Vladimir Gorshkov, Mikhail V. Gorshkov, Frank Kjeldsen
Published in: Journal of the American Society for Mass Spectrometry, 2020, ISSN 1044-0305
Publisher: Elsevier BV
DOI: 10.1021/jasms.0c00171

The Cytotoxicity of Metal Nanoparticles Depends on Their Synergistic Interactions

Author(s): Barbara Korzeniowska, Micaella P. Fonseca, Vladimir Gorshkov, Lilian Skytte, Kaare L. Rasmussen, Henrik D. Schrøder, Frank Kjeldsen
Published in: Particle & Particle Systems Characterization, Issue 37/8, 2020, Page(s) 2000135, ISSN 0934-0866
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ppsc.202000135

SuperQuant-assisted comparative proteome analysis of glioblastoma subpopulations allows for identification of potential novel therapeutic targets and cell markers

Author(s): Thiago Verano-Braga, Vladimir Gorshkov, Sune Munthe, Mia D. Sørensen, Bjarne W. Kristensen, Frank Kjeldsen
Published in: Oncotarget, Issue 9/10, 2018, ISSN 1949-2553
Publisher: Impact Journals
DOI: 10.18632/oncotarget.24321

Comparative proteomics as a tool for identifying specific alterations within interferon response pathways in human glioblastoma multiforme cells

Author(s): Irina A Tarasova, Alesya V Tereshkova, Anna A Lobas, Elizaveta M Solovyeva, Alena S Sidorenko, Vladimir Gorshkov, Frank Kjeldsen, Julia A Bubis, Mark V Ivanov, Irina Y Ilina, Sergei A Moshkovskii, Peter M Chumakov, Mikhail V Gorshkov
Published in: Oncotarget, Issue 9/2, 2018, ISSN 1949-2553
Publisher: Impact Journals
DOI: 10.18632/oncotarget.22751

Peptide de novo sequencing of mixture tandem mass spectra

Author(s): Vladimir Gorshkov, Stéphanie Yuki Kolbeck Hotta, Thiago Verano-Braga, Frank Kjeldsen
Published in: PROTEOMICS, Issue 16/18, 2016, Page(s) 2470-2479, ISSN 1615-9853
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.201500549

Co-exposure to silver nanoparticles and cadmium induce metabolic adaptation in HepG2 cells

Author(s): Renata Rank Miranda, Vladimir Gorshkov, Barbara Korzeniowska, Stefan J. Kempf, Francisco Filipak Neto, Frank Kjeldsen
Published in: Nanotoxicology, Issue 12/7, 2018, Page(s) 781-795, ISSN 1743-5390
Publisher: Informa Healthcare
DOI: 10.1080/17435390.2018.1489987

Toxicological interactions of silver nanoparticles and non-essential metals in human hepatocarcinoma cell line

Author(s): Renata Rank Miranda, Arandi Ginane Bezerra Jr, Ciro Alberto Oliveira Ribeiro, Marco Antônio Ferreira Randi, Carmen Lúcia Voigt, Lilian Skytte, Kaare Lund Rasmussen, Frank Kjeldsen, Francisco Filipak Neto
Published in: Toxicology in Vitro, Issue 40, 2017, Page(s) 134-143, ISSN 0887-2333
Publisher: Elsevier BV
DOI: 10.1016/j.tiv.2017.01.003

Uranyl photocleavage of phosphopeptides yields truncated C-terminally amidated peptide products

Author(s): Rasmus Linde Bang Elnegaard, Niels Erik Møllegaard, Qiang Zhang, Frank Kjeldsen, Thomas J.D. Jørgensen
Published in: ChemBioChem, 2017, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201700103

Ocular penetration of fluorometholone-loaded PEG-PLGA nanoparticles functionalized with cell-penetrating peptides

Author(s): Roberto Gonzalez-Pizarro, Graziella Parrotta, Rodrigo Vera, Elena Sánchez-López, Ruth Galindo, Frank Kjeldsen, Josefa Badia, Laura Baldoma, Marta Espina, María L García
Published in: Nanomedicine, Issue 14/23, 2019, Page(s) 3089-3104, ISSN 1743-5889
Publisher: Future Medicine Ltd.
DOI: 10.2217/nnm-2019-0201

DirectMS1: MS/MS-Free Identification of 1000 Proteins of Cellular Proteomes in 5 Minutes

Author(s): Mark V. Ivanov, Julia A. Bubis, Vladimir Gorshkov, Irina A. Tarasova, Lev I. Levitsky, Anna A. Lobas, Elizaveta M. Solovyeva, Marina L. Pridatchenko, Frank Kjeldsen, Mikhail V. Gorshkov
Published in: Analytical Chemistry, 2020, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.9b05095

Silver nanoparticle-induced expression of proteins related to oxidative stress and neurodegeneration in an in vitro human blood-brain barrier model

Author(s): Asif Manzoor Khan, Barbara Korzeniowska, Vladimir Gorshkov, Muhammad Tahir, Henrik Schrøder, Lilian Skytte, Kaare Lund Rasmussen, Surabhi Khandige, Jakob Møller-Jensen, Frank Kjeldsen
Published in: Nanotoxicology, Issue 13/2, 2019, Page(s) 221-239, ISSN 1743-5390
Publisher: Informa Healthcare
DOI: 10.1080/17435390.2018.1540728

Protein corona formed on silver nanoparticles in blood plasma is highly selective and resistant to physicochemical changes of the solution

Author(s): Vladimir Gorshkov, Julia A. Bubis, Elizaveta M. Solovyeva, Mikhail V. Gorshkov, Frank Kjeldsen
Published in: Environmental Science: Nano, Issue 6/4, 2019, Page(s) 1089-1098, ISSN 2051-8153
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8en01054d

Angiotensin-(1-7) oral treatment after experimental myocardial infarction leads to downregulation of CXCR4

Author(s): Diana Paola Gómez-Mendoza, Fúlvia Dias Marques, Marcella Nunes Melo-Braga, Richard R. Sprenger, Rubén Dario Sinisterra, Frank Kjeldsen, Robson Augusto Santos, Thiago Verano-Braga
Published in: Journal of Proteomics, Issue 208, 2019, Page(s) 103486, ISSN 1874-3919
Publisher: Elsevier BV
DOI: 10.1016/j.jprot.2019.103486

Fast and Robust Proteome Screening Platform Identifies Neutrophil Extracellular Trap Formation in the Lung in Response to Cobalt Ferrite Nanoparticles

Author(s): Anja M. Billing, Kristina B. Knudsen, Andrew J. Chetwynd, Laura-Jayne A. Ellis, Selina V.Y. Tang, Trine Berthing, Håkan Wallin, Iseult Lynch, Ulla Vogel, Frank Kjeldsen
Published in: ACS Nano, 2020, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.9b08818

Rpn4 and proteasome-mediated yeast resistance to ethanol includes regulation of autophagy

Author(s): Julia A. Bubis, Daria S. Spasskaya, Vladimir A. Gorshkov, Frank Kjeldsen, Aleksandra M. Kofanova, Dmitry S. Lekanov, Mikhail V. Gorshkov, Vadim L. Karpov, Irina A. Tarasova, Dmitry S. Karpov
Published in: Applied Microbiology and Biotechnology, 2020, ISSN 0175-7598
Publisher: Springer Verlag
DOI: 10.1007/s00253-020-10518-x

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