Formation and Characterization of Protein Post-Translational Modifications and Assessment of Cellular Responses by Application of Metals in Biological Systems

Informazioni relative al progetto

METALS

ID dell’accordo di sovvenzione: 646603

DOI

10.3030/646603

Progetto chiuso

Data della firma CE 8 Giugno 2015

Data di avvio 1 Settembre 2015

Data di completamento 28 Febbraio 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 798 750,00

Contributo UE

€ 1 798 750,00

Coordinato da

SYDDANSK UNIVERSITET
Denmark

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (17)

Elucidating the cellular response of silver nanoparticles as a potential combinatorial agent for cisplatin chemotherapy

Autori: Renata Rank Miranda, Micaella Pereira da Fonseca, Barbara Korzeniowska, Lilian Skytte, Kaare Lund Rasmussen, Frank Kjeldsen
Pubblicato in: Journal of Nanobiotechnology, Numero 18/1, 2020, ISSN 1477-3155
Editore: BioMed Central
DOI: 10.1186/s12951-020-00719-x

Cardiomyocyte Proteome Remodeling due to Isoproterenol‐Induced Cardiac Hypertrophy during the Compensated Phase

Autori: Ricardo Cambraia Parreira, Diana Paola Gómez‐Mendoza, Itamar Couto Guedes Jesus, Rafael Pereira Lemos, Anderson Kennedy Santos, Cristiana Perdigão Rezende, Henrique César Pereira Figueiredo, Mauro Cunha Xavier Pinto, Frank Kjeldsen, Silvia Guatimosim, Rodrigo Ribeiro Resende, Thiago Verano‐Braga
Pubblicato in: PROTEOMICS – Clinical Applications, Numero 14/4, 2020, Pagina/e 2000017, ISSN 1862-8346
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/prca.202000017

PhosphoShield: Improving Trypsin Digestion of Phosphoproteins by Shielding the Negatively Charged Phosphate Moiety

Autori: Julia A. Bubis, Vladimir Gorshkov, Mikhail V. Gorshkov, Frank Kjeldsen
Pubblicato in: Journal of the American Society for Mass Spectrometry, 2020, ISSN 1044-0305
Editore: Elsevier BV
DOI: 10.1021/jasms.0c00171

The Cytotoxicity of Metal Nanoparticles Depends on Their Synergistic Interactions

Autori: Barbara Korzeniowska, Micaella P. Fonseca, Vladimir Gorshkov, Lilian Skytte, Kaare L. Rasmussen, Henrik D. Schrøder, Frank Kjeldsen
Pubblicato in: Particle & Particle Systems Characterization, Numero 37/8, 2020, Pagina/e 2000135, ISSN 0934-0866
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/ppsc.202000135

SuperQuant-assisted comparative proteome analysis of glioblastoma subpopulations allows for identification of potential novel therapeutic targets and cell markers

Autori: Thiago Verano-Braga, Vladimir Gorshkov, Sune Munthe, Mia D. Sørensen, Bjarne W. Kristensen, Frank Kjeldsen
Pubblicato in: Oncotarget, Numero 9/10, 2018, ISSN 1949-2553
Editore: Impact Journals
DOI: 10.18632/oncotarget.24321

Comparative proteomics as a tool for identifying specific alterations within interferon response pathways in human glioblastoma multiforme cells

Autori: Irina A Tarasova, Alesya V Tereshkova, Anna A Lobas, Elizaveta M Solovyeva, Alena S Sidorenko, Vladimir Gorshkov, Frank Kjeldsen, Julia A Bubis, Mark V Ivanov, Irina Y Ilina, Sergei A Moshkovskii, Peter M Chumakov, Mikhail V Gorshkov
Pubblicato in: Oncotarget, Numero 9/2, 2018, ISSN 1949-2553
Editore: Impact Journals
DOI: 10.18632/oncotarget.22751

Peptide de novo sequencing of mixture tandem mass spectra

Autori: Vladimir Gorshkov, Stéphanie Yuki Kolbeck Hotta, Thiago Verano-Braga, Frank Kjeldsen
Pubblicato in: PROTEOMICS, Numero 16/18, 2016, Pagina/e 2470-2479, ISSN 1615-9853
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.201500549

Co-exposure to silver nanoparticles and cadmium induce metabolic adaptation in HepG2 cells

Autori: Renata Rank Miranda, Vladimir Gorshkov, Barbara Korzeniowska, Stefan J. Kempf, Francisco Filipak Neto, Frank Kjeldsen
Pubblicato in: Nanotoxicology, Numero 12/7, 2018, Pagina/e 781-795, ISSN 1743-5390
Editore: Informa Healthcare
DOI: 10.1080/17435390.2018.1489987

Toxicological interactions of silver nanoparticles and non-essential metals in human hepatocarcinoma cell line

Autori: Renata Rank Miranda, Arandi Ginane Bezerra Jr, Ciro Alberto Oliveira Ribeiro, Marco Antônio Ferreira Randi, Carmen Lúcia Voigt, Lilian Skytte, Kaare Lund Rasmussen, Frank Kjeldsen, Francisco Filipak Neto
Pubblicato in: Toxicology in Vitro, Numero 40, 2017, Pagina/e 134-143, ISSN 0887-2333
Editore: Elsevier BV
DOI: 10.1016/j.tiv.2017.01.003

Uranyl photocleavage of phosphopeptides yields truncated C-terminally amidated peptide products

Autori: Rasmus Linde Bang Elnegaard, Niels Erik Møllegaard, Qiang Zhang, Frank Kjeldsen, Thomas J.D. Jørgensen
Pubblicato in: ChemBioChem, 2017, ISSN 1439-4227
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201700103

Ocular penetration of fluorometholone-loaded PEG-PLGA nanoparticles functionalized with cell-penetrating peptides

Autori: Roberto Gonzalez-Pizarro, Graziella Parrotta, Rodrigo Vera, Elena Sánchez-López, Ruth Galindo, Frank Kjeldsen, Josefa Badia, Laura Baldoma, Marta Espina, María L García
Pubblicato in: Nanomedicine, Numero 14/23, 2019, Pagina/e 3089-3104, ISSN 1743-5889
Editore: Future Medicine Ltd.
DOI: 10.2217/nnm-2019-0201

DirectMS1: MS/MS-Free Identification of 1000 Proteins of Cellular Proteomes in 5 Minutes

Autori: Mark V. Ivanov, Julia A. Bubis, Vladimir Gorshkov, Irina A. Tarasova, Lev I. Levitsky, Anna A. Lobas, Elizaveta M. Solovyeva, Marina L. Pridatchenko, Frank Kjeldsen, Mikhail V. Gorshkov
Pubblicato in: Analytical Chemistry, 2020, ISSN 0003-2700
Editore: American Chemical Society
DOI: 10.1021/acs.analchem.9b05095

Silver nanoparticle-induced expression of proteins related to oxidative stress and neurodegeneration in an in vitro human blood-brain barrier model

Autori: Asif Manzoor Khan, Barbara Korzeniowska, Vladimir Gorshkov, Muhammad Tahir, Henrik Schrøder, Lilian Skytte, Kaare Lund Rasmussen, Surabhi Khandige, Jakob Møller-Jensen, Frank Kjeldsen
Pubblicato in: Nanotoxicology, Numero 13/2, 2019, Pagina/e 221-239, ISSN 1743-5390
Editore: Informa Healthcare
DOI: 10.1080/17435390.2018.1540728

Protein corona formed on silver nanoparticles in blood plasma is highly selective and resistant to physicochemical changes of the solution

Autori: Vladimir Gorshkov, Julia A. Bubis, Elizaveta M. Solovyeva, Mikhail V. Gorshkov, Frank Kjeldsen
Pubblicato in: Environmental Science: Nano, Numero 6/4, 2019, Pagina/e 1089-1098, ISSN 2051-8153
Editore: Royal Society of Chemistry
DOI: 10.1039/c8en01054d

Angiotensin-(1-7) oral treatment after experimental myocardial infarction leads to downregulation of CXCR4

Autori: Diana Paola Gómez-Mendoza, Fúlvia Dias Marques, Marcella Nunes Melo-Braga, Richard R. Sprenger, Rubén Dario Sinisterra, Frank Kjeldsen, Robson Augusto Santos, Thiago Verano-Braga
Pubblicato in: Journal of Proteomics, Numero 208, 2019, Pagina/e 103486, ISSN 1874-3919
Editore: Elsevier BV
DOI: 10.1016/j.jprot.2019.103486

Fast and Robust Proteome Screening Platform Identifies Neutrophil Extracellular Trap Formation in the Lung in Response to Cobalt Ferrite Nanoparticles

Autori: Anja M. Billing, Kristina B. Knudsen, Andrew J. Chetwynd, Laura-Jayne A. Ellis, Selina V.Y. Tang, Trine Berthing, Håkan Wallin, Iseult Lynch, Ulla Vogel, Frank Kjeldsen
Pubblicato in: ACS Nano, 2020, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.9b08818

Rpn4 and proteasome-mediated yeast resistance to ethanol includes regulation of autophagy

Autori: Julia A. Bubis, Daria S. Spasskaya, Vladimir A. Gorshkov, Frank Kjeldsen, Aleksandra M. Kofanova, Dmitry S. Lekanov, Mikhail V. Gorshkov, Vadim L. Karpov, Irina A. Tarasova, Dmitry S. Karpov
Pubblicato in: Applied Microbiology and Biotechnology, 2020, ISSN 0175-7598
Editore: Springer Verlag
DOI: 10.1007/s00253-020-10518-x