Cancer treatment during pregnancy: from fetal safety to maternal efficacy

Información del proyecto

CRADLE

Identificador del acuerdo de subvención: 647047

DOI

10.3030/647047

Proyecto cerrado

Fecha de la firma de la CE 25 Septiembre 2015

Fecha de inicio 1 Octubre 2015

Fecha de finalización 31 Marzo 2021

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 000 000,00

Aportación de la UE

€ 2 000 000,00

Coordinado por

KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (23)

The impact of cancer and chemotherapy during pregnancy on child neurodevelopment: A multimodal neuroimaging analysis

Autores: J. Blommaert, A. Radwan, C. Sleurs, C. Maggen, M. van Gerwen, V. Wolters, D. Christiaens, R. Peeters, P. Dupont, S. Sunaert, K. Van Calsteren, S. Deprez, F. Amant
Publicado en: EClinicalMedicine, Edición 28, 2020, Página(s) 100598, ISSN 2589-5370
Editor: Elsevier
DOI: 10.1016/j.eclinm.2020.100598

Pregnancy and Cancer: the INCIP Project

Autores: Charlotte Maggen, Vera E. R. A. Wolters, Elyce Cardonick, Monica Fumagalli, Michael J. Halaska, Christianne A. R. Lok, Jorine de Haan, Katrien Van Tornout, Kristel Van Calsteren, Frédéric Amant
Publicado en: Current Oncology Reports, Edición 22/2, 2020, ISSN 1523-3790
Editor: Current Science Inc.
DOI: 10.1007/s11912-020-0862-7

Long-term neurodevelopmental outcome after prenatal exposure to maternal hematological malignancies with or without cytotoxic treatment

Autores: Mathilde van Gerwen, Evangeline Huis in ‘t Veld, Martine van Grotel, Marry M. van den Heuvel-Eibrink, Kristel Van Calsteren, Charlotte Maggen, Vit Drochytek, Giovanna Scarfone, Camilla Fontana, Robert Fruscio, Elyce Cardonick, Elisabeth M. van Dijk-Lokkart, Frédéric Amant
Publicado en: Child Neuropsychology, 2021, Página(s) 1-12, ISSN 0929-7049
Editor: Swets & Zeitlinger
DOI: 10.1080/09297049.2021.1902489

Data describing child development at 6 years after maternal cancer diagnosis and treatment during pregnancy

Autores: Mathilde van Gerwen, Tineke Vandenbroucke, Magali Verheecke, Kristel Van Calsteren, Michael J. Halaska, Monica Fumagalli, Robert Fruscio, Amarendra Gandhi, Margreet Veening, Lieven Lagae, Petronella B. Ottevanger, Jens-Uwe Voigt, Jorine de Haan, Mina M. Gziri, Charlotte Maggen, Luc Mertens, Gunnar Naulaers, Laurence Claes, Frédéric Amant
Publicado en: Data in Brief, Edición 32, 2020, Página(s) 106209, ISSN 2352-3409
Editor: Elsevier BV
DOI: 10.1016/j.dib.2020.106209

Maternal and neonatal outcomes in 80 patients diagnosed with non‐Hodgkin lymphoma during pregnancy: results from the International Network of Cancer, Infertility and Pregnancy

Autores: Charlotte Maggen, Daan Dierickx, Elyce Cardonick, Mina Mhallem Gziri, Alvaro Cabrera‐Garcia, Roman G. Shmakov, Irit Avivi, Bianca Masturzo, Johannes J. Duvekot, Petronella B. Ottevanger, Andie O’Laughlin, Evgeniya Polushkina, Kristel Van Calsteren, F.J. Sherida H. Woei‐A‐Jin, Frédéric Amant
Publicado en: British Journal of Haematology, Edición 193/1, 2021, Página(s) 52-62, ISSN 0007-1048
Editor: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17103

Obstetric and maternal outcomes in patients diagnosed with Hodgkin lymphoma during pregnancy: a multicentre, retrospective, cohort study

Autores: Charlotte Maggen, Daan Dierickx, Pieternella Lugtenburg, Annouschka Laenen, Elyce Cardonick, Roman G Smakov, Mar Bellido, Alvaro Cabrera-Garcia, Mina Mhallem Gziri, Michael J Halaska, Petronella B Ottevanger, Kristel Van Calsteren, Andie O'Laughlin, Evgeniya Polushkina, Laura Van Dam, Irit Avivi, Peter Vandenberghe, F J Sherida H Woei-A-Jin, Frédéric Amant
Publicado en: The Lancet Haematology, Edición 6/11, 2019, Página(s) e551-e561, ISSN 2352-3026
Editor: Elsevier Limited
DOI: 10.1016/s2352-3026(19)30195-4

Corrigendum to ‘Genetic and microscopic assessment of the human chemotherapy-exposed placenta reveals possible pathways contributive to fetal growth restriction’[YPLAC 64C (2018) 61–70]

Autores: M. Verheecke, A. Cortès Calabuig, J. Finalet Ferreiro, V. Brys, R. Van Bree, G. Verbist, T. Everaert, L. Leemans, M.M. Gziri, I. Boere, M.J. Halaska, J. Van Houdt, F. Amant, K. Van Calsteren
Publicado en: Placenta, Edición 69, 2018, Página(s) 117, ISSN 0143-4004
Editor: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.placenta.2018.07.008

Executive functioning in 6 year old children exposed to chemotherapy in utero

Autores: Mathilde van Gerwen, Tineke Vandenbroucke, An-sofie Gorissen, Martine van Grotel, Marry van den Heuvel-Eibrink, Emma Verwaaijen, Madeleine van der Perk, Kristel Van Calsteren, Elisabeth M. van Dijk-Lokkart, Frédéric Amant
Publicado en: Early Human Development, Edición 151, 2020, Página(s) 105198, ISSN 0378-3782
Editor: Elsevier BV
DOI: 10.1016/j.earlhumdev.2020.105198

Maternal and obstetrical outcome in 35 cases of well‐differentiated thyroid carcinoma during pregnancy

Autores: Jan Boucek, Jorine Haan, Michael J. Halaska, Jan Plzak, Kristel Calsteren, Christianne J. M. Groot, Karina Dahl Steffensen, Robert Fruscio, Elske T. Massolt, Philipp Klaritsch, Paolo Zola, Frédéric Amant
Publicado en: The Laryngoscope, Edición 128/6, 2017, Página(s) 1493-1500, ISSN 0023-852X
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1002/lary.26936

Long-term impact of prenatal exposure to chemotherapy on executive functioning: An ERP study

Autores: Jeroen Blommaert, Rob Zink, Sabine Deprez, Ivan Myatchin, Patrick Dupont, Tineke Vandenbroucke, Charlotte Sleurs, Kristel Van Calsteren, Frédéric Amant, Lieven Lagae
Publicado en: Clinical Neurophysiology, Edición 130/9, 2019, Página(s) 1655-1664, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2019.06.012

Maternal and Neonatal Outcome after the Use of G-CSF for Cancer Treatment during Pregnancy

Autores: Claudia Berends, Charlotte Maggen, Christianne A. R. Lok, Mathilde van Gerwen, Ingrid A. Boere, Vera E. R. A. Wolters, Kristel Van Calsteren, Heidi Segers, Marry M. van den Heuvel-Eibrink, Rebecca C. Painter, Mina Mhallem Gziri, Frédéric Amant
Publicado en: Cancers, Edición 13/6, 2021, Página(s) 1214, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13061214

Population Pharmacokinetics of Docetaxel, Paclitaxel, Doxorubicin and Epirubicin in Pregnant Women with Cancer: A Study from the International Network of Cancer, Infertility and Pregnancy (INCIP)

Autores: Julie M. Janssen, Kristel Van Calsteren, Thomas P. C. Dorlo, Michael J. Halaska, Robert Fruscio, Petronella Ottevanger, Carolien P. Schröder, Ingrid Boere, Petronella O. Witteveen, Rebecca C. Painter, Ruud Bekkers, Vit Drochytek, Jos H. Beijnen, Alwin D. R. Huitema, Frederic C. H. Amant
Publicado en: Clinical Pharmacokinetics, 2021, ISSN 0312-5963
Editor: Adis International Ltd.
DOI: 10.1007/s40262-020-00961-4

Oncological management and obstetric and neonatal outcomes for women diagnosed with cancer during pregnancy: a 20-year international cohort study of 1170 patients

Autores: Jorine de Haan, Magali Verheecke, Kristel Van Calsteren, Ben Van Calster, Roman G Shmakov, Mina Mhallem Gziri, Michael J Halaska, Robert Fruscio, Christianne A R Lok, Ingrid A Boere, Paolo Zola, Petronella B Ottevanger, Christianne J M de Groot, Fedro A Peccatori, Karina Dahl Steffensen, Elyce H Cardonick, Evgeniya Polushkina, Lukas Rob, Lorenzo Ceppi, Gennady T Sukhikh, Sileny N Han, Frédéric A
Publicado en: The Lancet Oncology, Edición 19/3, 2018, Página(s) 337-346, ISSN 1470-2045
Editor: The Lancet Publishing Group
DOI: 10.1016/S1470-2045(18)30059-7

Genetic and microscopic assessment of the human chemotherapy-exposed placenta reveals possible pathways contributive to fetal growth restriction

Autores: M. Verheecke, A. Cortès Calabuig, J. Finalet Ferreiro, V. Brys, R. Van Bree, G. Verbist, T. Everaert, L. Leemans, M.M. Gziri, I. Boere, M.J. Halaska, J. Vanhoudt, F. Amant, K. Van Calsteren
Publicado en: Placenta, Edición 64, 2018, Página(s) 61-70, ISSN 0143-4004
Editor: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.placenta.2018.03.002

Feasibility of whole-body diffusion-weighted MRI for detection of primary tumour, nodal and distant metastases in women with cancer during pregnancy: a pilot study

Autores: Sileny N. Han, Frédéric Amant, Katrijn Michielsen, Frederik De Keyzer, Steffen Fieuws, Kristel Van Calsteren, Raphaëla C. Dresen, Mina Mhallem Gziri, Vincent Vandecaveye
Publicado en: European Radiology, Edición 28/5, 2018, Página(s) 1862-1874, ISSN 0938-7994
Editor: Springer Verlag
DOI: 10.1007/s00330-017-5126-z

Acute Drug Effects on the Human Placental Tissue: The Development of a Placental Murine Xenograft Model

Autores: Magali Verheecke, Els Hermans, Sandra Tuyaerts, Erika Souche, Rita Van Bree, Godelieve Verbist, Tina Everaert, Jeroen Van Houdt, Kristel Van Calsteren, Frederic Amant
Publicado en: Reproductive Sciences, 2018, Página(s) 193371911875677, ISSN 1933-7191
Editor: SAGE Publications
DOI: 10.1177/1933719118756771

Effects of cancer treatment during pregnancy on fetal and child development

Autores: Tineke Vandenbroucke, Magali Verheecke, Monica Fumagalli, Christianne Lok, Frédéric Amant
Publicado en: The Lancet Child & Adolescent Health, Edición 1/4, 2017, Página(s) 302-310, ISSN 2352-4642
Editor: Elsevier SCI LTD
DOI: 10.1016/S2352-4642(17)30091-3

Integration and validation of the ex vivo human placenta perfusion model

Autores: Sigrid Conings, Frédéric Amant, Pieter Annaert, Kristel Van Calsteren
Publicado en: Journal of Pharmacological and Toxicological Methods, Edición 88, 2017, Página(s) 25-31, ISSN 1056-8719
Editor: Elsevier BV
DOI: 10.1016/j.vascn.2017.05.002

Psychological distress and cognitive coping in pregnant women diagnosed with cancer and their partners

Autores: Tineke Vandenbroucke, Sileny N. Han, Kristel Van Calsteren, Tom F. Wilderjans, Bea R.H. Van den Bergh, Laurence Claes, Frédéric Amant
Publicado en: Psycho-Oncology, Edición vol. 26, issue 8, 2016, Página(s) 1215-1221, ISSN 1057-9249
Editor: John Wiley & Sons Inc.
DOI: 10.1002/pon.4301

Postpartum breast cancer: mechanisms underlying its worse prognosis, treatment implications, and fertility preservation

Autores: Hanne Lefrère, Liesbeth Lenaerts, Virginia F Borges, Pepper Schedin, Patrick Neven, Frédéric Amant
Publicado en: International Journal of Gynecologic Cancer, Edición 31/3, 2021, Página(s) 412-422, ISSN 1048-891X
Editor: Blackwell Publishing Inc.
DOI: 10.1136/ijgc-2020-002072

Age‐dependent brain volume and neuropsychological changes after chemotherapy in breast cancer patients

Autores: Jeroen Blommaert, Gwen Schroyen, Mathieu Vandenbulcke, Ahmed Radwan, Ann Smeets, Ron Peeters, Charlotte Sleurs, Patrick Neven, Hans Wildiers, Frédéric Amant, Stefan Sunaert, Sabine Deprez
Publicado en: Human Brain Mapping, Edición 40/17, 2019, Página(s) 4994-5010, ISSN 1065-9471
Editor: John Wiley & Sons Inc.
DOI: 10.1002/hbm.24753

Gastric cancer during pregnancy: A report on 13 cases and review of the literature with focus on chemotherapy during pregnancy

Autores: Charlotte Maggen, Christianne A. Lok, Elyce Cardonick, Mathilde van Gerwen, Petronella B. Ottevanger, Ingrid A. Boere, Martin Koskas, Michael J. Halaska, Robert Fruscio, Mina M. Gziri, Petronella O. Witteveen, Kristel Van Calsteren, Frédéric Amant
Publicado en: Acta Obstetricia et Gynecologica Scandinavica, Edición 99/1, 2019, Página(s) 79-88, ISSN 0001-6349
Editor: Wiley-Blackwell
DOI: 10.1111/aogs.13731

Child development at 6 years after maternal cancer diagnosis and treatment during pregnancy

Autores: Tineke Vandenbroucke, Magali Verheecke, Mathilde van Gerwen, Kristel Van Calsteren, Michael J. Halaska, Monica Fumagalli, Robert Fruscio, Amarendra Gandhi, Margreet Veening, Lieven Lagae, Petronella B. Ottevanger, Jens-Uwe Voigt, Jorine de Haan, Mina M. Gziri, Charlotte Maggen, Luc Mertens, Gunnar Naulaers, Laurence Claes, Frédéric Amant, Jeroen Blommaert, Jana Dekrem, Frederic Goffin, Vincent R
Publicado en: European Journal of Cancer, Edición 138, 2020, Página(s) 57-67, ISSN 0959-8049
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.ejca.2020.07.004