Localization in biomechanics and mechanobiology of aneurysms: Towards personalized medicine

Project Information

BIOLOCHANICS

Grant agreement ID: 647067

DOI

10.3030/647067

Project closed

EC signature date 22 April 2015

Start date 1 May 2015

End date 31 December 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 396,00

EU contribution

€ 1 999 396,00

Coordinated by

ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (28)

In vitro histomechanical effects of enzymatic degradation in carotid arteries during inflation tests with pulsatile loading

Author(s): Olfa Trabelsi, Virginie Dumas, Edouard Breysse, Norbert Laroche, Stephane Avril
Published in: Journal of the Mechanical Behavior of Biomedical Materials, Issue 103, 2020, Page(s) 103550, ISSN 1751-6161
Publisher: Elsevier BV
DOI: 10.1016/j.jmbbm.2019.103550

Constrained mixture modeling affects material parameter identification from planar biaxial tests

Author(s): Lauranne Maes, Heleen Fehervary, Julie Vastmans, S. Jamaleddin Mousavi, Stéphane Avril, Nele Famaey
Published in: Journal of the Mechanical Behavior of Biomedical Materials, Issue 95, 2019, Page(s) 124-135, ISSN 1751-6161
Publisher: Elsevier BV
DOI: 10.1016/j.jmbbm.2019.03.029

Traction Force Measurements of Human Aortic Smooth Muscle Cells Reveal a Motor-Clutch Behavior

Author(s): Petit Claudie, Guignandon Alain, Avril St閜hane
Published in: Molecular & Cellular Biomechanics, Issue 16/2, 2019, Page(s) 87-108, ISSN 1556-5300
Publisher: SAINBIOSE-ENSMSE
DOI: 10.32604/mcb.2019.06415

Regulation of SMC traction forces in human aortic thoracic aneurysms

Author(s): Claudie Petit, Ali-Akbar Karkhaneh Yousefi, Olfa Ben Moussa, Jean-Baptiste Michel, Alain Guignandon, Stéphane Avril
Published in: Biomechanics and Modeling in Mechanobiology, 2021, ISSN 1617-7959
Publisher: Springer Verlag
DOI: 10.1007/s10237-020-01412-6

An implicit 3D corotational formulation for frictional contact dynamics of beams against rigid surfaces using discrete signed distance fields

Author(s): Miquel Aguirre, Stéphane Avril
Published in: Computer Methods in Applied Mechanics and Engineering, Issue 371, 2020, Page(s) 113275, ISSN 0045-7825
Publisher: Elsevier BV
DOI: 10.1016/j.cma.2020.113275

Characteristics of thoracic aortic aneurysm rupture in vitro

Author(s): Yuanming Luo, Ambroise Duprey, Stéphane Avril, Jia Lu
Published in: Acta Biomaterialia, Issue 42, 2016, Page(s) 286-295, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2016.06.036

In Vitro Measurement of Strain Localization Preceding Dissection of the Aortic Wall Subjected to Radial Tension

Author(s): M. Di Giuseppe, M. Zingales, S. Pasta, S. Avril
Published in: Experimental Mechanics, Issue 61/1, 2021, Page(s) 119-130, ISSN 0014-4851
Publisher: Sage Science Press
DOI: 10.1007/s11340-020-00641-1

Relationship Between Ascending Thoracic Aortic Aneurysms Hemodynamics and Biomechanical Properties

Author(s): Francesca Condemi, Salvatore Campisi, Magalie Viallon, Pierre Croisille, Stephane Avril
Published in: IEEE Transactions on Biomedical Engineering, Issue 67/4, 2020, Page(s) 949-956, ISSN 0018-9294
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2019.2924955

Patient-specific stress analyses in the ascending thoracic aorta using a finite-element implementation of the constrained mixture theory

Author(s): S. Jamaleddin Mousavi, Stéphane Avril
Published in: Biomechanics and Modeling in Mechanobiology, Issue 16/5, 2017, Page(s) 1765-1777, ISSN 1617-7959
Publisher: Springer Verlag
DOI: 10.1007/s10237-017-0918-2

A comprehensive study of layer-specific morphological changes in the microstructure of carotid arteries under uniaxial load

Author(s): Witold Krasny, Claire Morin, Hélène Magoariec, Stéphane Avril
Published in: Acta Biomaterialia, Issue 57, 2017, Page(s) 342-351, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2017.04.033

Fluid- and Biomechanical Analysis of Ascending Thoracic Aorta Aneurysm with Concomitant Aortic Insufficiency

Author(s): F. Condemi, S. Campisi, M. Viallon, T. Troalen, G. Xuexin, A. J. Barker, M. Markl, P. Croisille, O. Trabelsi, C. Cavinato, A. Duprey, S. Avril
Published in: Annals of Biomedical Engineering, Issue 45/12, 2017, Page(s) 2921-2932, ISSN 0090-6964
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10439-017-1913-6

A non-invasive methodology for ATAA rupture risk estimation

Author(s): O. Trabelsi, M. Gutierrez, S. Farzaneh, A. Duprey, S. Avril
Published in: Journal of Biomechanics, Issue 66, 2018, Page(s) 119-126, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2017.11.012

Kinematics of collagen fibers in carotid arteries under tension-inflation loading

Author(s): Witold Krasny, Hélène Magoariec, Claire Morin, Stéphane Avril
Published in: Journal of the Mechanical Behavior of Biomedical Materials, Issue 77, 2018, Page(s) 718-726, ISSN 1751-6161
Publisher: Elsevier BV
DOI: 10.1016/j.jmbbm.2017.08.014

Computational predictions of damage propagation preceding dissection of ascending thoracic aortic aneurysms

Author(s): S. Jamaleddin Mousavi, Solmaz Farzaneh, Stéphane Avril
Published in: International Journal for Numerical Methods in Biomedical Engineering, 2017, Page(s) e2944, ISSN 2040-7939
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.2944

Biaxial rupture properties of ascending thoracic aortic aneurysms

Author(s): Ambroise Duprey, Olfa Trabelsi, Marco Vola, Jean-Pierre Favre, Stéphane Avril
Published in: Acta Biomaterialia, Issue 42, 2016, Page(s) 273-285, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2016.06.028

Novel Methodology for Characterizing Regional Variations in the Material Properties of Murine Aortas

Author(s): Matthew R. Bersi, Chiara Bellini, Paolo Di Achille, Jay D. Humphrey, Katia Genovese, Stéphane Avril
Published in: Journal of Biomechanical Engineering, Issue 138/7, 2016, Page(s) 071005, ISSN 0148-0731
Publisher: ASME
DOI: 10.1115/1.4033674

Three-Dimensional Full-Field Strain Measurements across a Whole Porcine Aorta Subjected to Tensile Loading Using Optical Coherence Tomography–Digital Volume Correlation

Author(s): Víctor A. Acosta Santamaría, María Flechas García, Jérôme Molimard, Stephane Avril
Published in: Frontiers in Mechanical Engineering, Issue 4, 2018, ISSN 2297-3079
Publisher: Frontiers Media S.A
DOI: 10.3389/fmech.2018.00003

Model reduction methodology for computational simulations of endovascular repair

Author(s): V. A. Acosta Santamaría, G. Daniel, D. Perrin, J. N. Albertini, E. Rosset, S. Avril
Published in: Computer Methods in Biomechanics and Biomedical Engineering, Issue 21/2, 2018, Page(s) 139-148, ISSN 1025-5842
Publisher: Taylor & Francis
DOI: 10.1080/10255842.2018.1427740

Numerical simulation of arterial remodeling in pulmonary autografts

Author(s): Nele Famaey, Julie Vastmans, Heleen Fehervary, Lauranne Maes, Emma Vanderveken, Filip Rega, S. Jamaleddin Mousavi, Stéphane Avril
Published in: ZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, Issue 98/12, 2018, Page(s) 2239-2257, ISSN 0044-2267
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/zamm.201700351

Inverse identification of local stiffness across ascending thoracic aortic aneurysms

Author(s): Solmaz Farzaneh, Olfa Trabelsi, Stéphane Avril
Published in: Biomechanics and Modeling in Mechanobiology, Issue 18/1, 2019, Page(s) 137-153, ISSN 1617-7959
Publisher: Springer Verlag
DOI: 10.1007/s10237-018-1073-0

Local variations in material and structural properties characterize murine thoracic aortic aneurysm mechanics

Author(s): Matthew R. Bersi, Chiara Bellini, Jay D. Humphrey, Stéphane Avril
Published in: Biomechanics and Modeling in Mechanobiology, Issue 18/1, 2019, Page(s) 203-218, ISSN 1617-7959
Publisher: Springer Verlag
DOI: 10.1007/s10237-018-1077-9

Evaluation of Peak Wall Stress in an Ascending Thoracic Aortic Aneurysm Using FSI Simulations: Effects of Aortic Stiffness and Peripheral Resistance

Author(s): Rossella Campobasso, Francesca Condemi, Magalie Viallon, Pierre Croisille, Salvatore Campisi, Stéphane Avril
Published in: Cardiovascular Engineering and Technology, Issue 9/4, 2018, Page(s) 707-722, ISSN 1869-408X
Publisher: Springer Pub. Co.,
DOI: 10.1007/s13239-018-00385-z

Ascending thoracic aorta aneurysm repair induces positive hemodynamic outcomes in a patient with unchanged bicuspid aortic valve

Author(s): Francesca Condemi, Salvatore Campisi, Magalie Viallon, Pierre Croisille, Jean-François Fuzelier, Stéphane Avril
Published in: Journal of Biomechanics, Issue 81, 2018, Page(s) 145-148, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2018.09.022

Identifying Local Arterial Stiffness to Assess the Risk of Rupture of Ascending Thoracic Aortic Aneurysms

Author(s): Solmaz Farzaneh, Olfa Trabelsi, Bertrand Chavent, Stéphane Avril
Published in: Annals of Biomedical Engineering, 2019, ISSN 0090-6964
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10439-019-02204-5

Characterization of chemoelastic effects in arteries using digital volume correlation and optical coherence tomography

Author(s): Víctor A. Acosta Santamaría, María Flechas García, Jérôme Molimard, Stéphane Avril
Published in: Acta Biomaterialia, Issue 102, 2020, Page(s) 127-137, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2019.11.049

Gradient-enhanced continuum models of healing in damaged soft tissues

Author(s): Yiqian He, Di Zuo, Klaus Hackl, Haitian Yang, S. Jamaleddin Mousavi, Stéphane Avril
Published in: Biomechanics and Modeling in Mechanobiology, Issue 18/5, 2019, Page(s) 1443-1460, ISSN 1617-7959
Publisher: Springer Verlag
DOI: 10.1007/s10237-019-01155-z

Multimodality Imaging-Based Characterization of Regional Material Properties in a Murine Model of Aortic Dissection

Author(s): Matthew R. Bersi, Víctor A. Acosta Santamaría, Karl Marback, Paolo Di Achille, Evan H. Phillips, Craig J. Goergen, Jay D. Humphrey, Stéphane Avril
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-65624-7

A Chemomechanobiological Model of the Long-Term Healing Response of Arterial Tissue to a Clamping Injury

Author(s): Lauranne Maes, Julie Vastmans, Stéphane Avril, Nele Famaey
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2021, ISSN 2296-4185
Publisher: Frontiers In Bioengineering And Biotechnology
DOI: 10.3389/fbioe.2020.589889

Non-peer reviewed articles (1)

Corrigendum to “A non-invasive methodology for ATAA rupture risk estimation” [J. Biomech. 66 (2018) 119–126]

Author(s): O. Trabelsi, M. Gutierrez, S. Farzaneh, A. Duprey, S. Avril
Published in: Journal of Biomechanics, Issue 72, 2018, Page(s) 274, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2018.03.041

Book chapters (1)

Hyperelasticity of Soft Tissues and Related Inverse Problems

Author(s): Stéphane Avril
Published in: 2017, Page(s) 37-66
Publisher: Springer International Publishing
DOI: 10.1007/978-3-319-45071-1_2