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3D Bioprinting of JOINT Replacements

Publicaciones

Towards complex and multi-scale biological constructs combining diverse biofabrication technologies.

Autores: R. Levato
Publicado en: Interactive Materials – First in Translation, Issue 2019, 2019

Tissue adhesive bioink as cell carrier and cartilage-binding glue for bioprinting and chondral regeneration.

Autores: Abinzano F, Lim K, Núñez Bernal P, Atienza Roca P, Sánchez A, Otto I, Woodfield T, Malda J, Levato R.
Publicado en: 15th ICRS World Congress, Issue 2019, 2019

Artificial myocardial muscle using 3D printed micro-fiber scaffolds with human iPS-derived cardiomyocytes.

Autores: M Castilho, Mil A, Maher M, Metz C, Hochleitner G, Groll J, Ito I, Sluijter J, Malda J
Publicado en: 8th World Congress of Biomechanics, Issue 2018, 2018

Development of Auricular Implant Using Smart Scaffold Design, Progenitor Cells and 3D Bioprinting Strategies

Autores: I.A. Otto, M. de Ruijter, P. Nuñez Bernal, M. Kon, C.C. Breugem, R. Levato, J. Malda.
Publicado en: ISBF conference, Issue 2018, 2018

Osteochondral Plug: a multi-scale, single-step fabrication process.

Autores: M. de Ruijter, Inge Dokter, Paweena Diloksumpan, Riccardo Levato, Miguel Castilho, Jos Malda.
Publicado en: Annual meeting of the International Society for Biofabrication, Issue 2018, 2018

Impact of pore architectures in 3D printed bioceramic scaffolds on orthotopic bone regeneration in an equine model

Autores: R. Levato, P. Diloksumpan, R. Vindas Bolaños, S. Cokelaere, B. Pouran, J. de Grauw, M. van Rijen, P. R. van Weeren, J. Malda
Publicado en: International Conference on Biofabrication, Issue 2019, 2019

Cartilage tissue engineering using auricular cartilage progenitor cells in a 3D hydrogel system.

Autores: Levato R, Otto I, Webb R, Khan IM, Breugem C, Malda J.
Publicado en: 14th World Congress of the International Cartilage Repair Society, Issue 2018, 2018

Biofabrication of 3D convoluted in-hydrogel vessel-like microfluidic channels via digital light processing bioprinting

Autores:  Levato R, Lim K, Gawlitta D, Woodfield T, Malda J.
Publicado en: 5th TERMIS World Congress, Issue 2018, 2018

Orthotopic bone regeneration within 3D printed region-dependent porous bioceramic scaffolds in an equine model (TERMIS)

Autores: P. Diloksumpan, R. Vindas Bolaños, S. Cokelaere, B. Pouran, J. de Grauw, M. van Rijen, P. R. van Weeren, R. Levato, J. Malda
Publicado en: TERMIS EU 2019, Issue 2019, 2019

Tissue adhesive bioink as cell carrier and cartilage-binding glue for bioprinting and chondral regeneration (ISBF).

Autores: Abinzano F, Lim K, Nunez-Bernal P, Atienza-Roca P, Alibllos-Sanchez A, Otto I, Woodfield T, Malda J, Levato R
Publicado en: International Conference on Biofabrication, Issue 2019, 2019

Novel volumetric bioprinting approach for ultra-fast biofabrication of complex tissue architectures.

Autores: Bernal P, Delrot P, Loterie D, Li Y, Malda J, Moser C, Levato R.
Publicado en: 11th World Biomaterials Congress, Issue 2020, 2020

Determining the Ideal Bioink for Myocardial Construct Biofabrication.

Autores: M. J. Ainsworth, N.Chirico, I. Dokter, I. H. van Adrichem, M.Olenic, J. P. G. Sluijter, J. Malda, A. van Mil, M. Castilho.
Publicado en: NBTE Annual Meeting, Issue 2019, 2019

High-speed biofabrication of complex tissue structures through novel volumetric bioprinting approach. 

Autores: P. N. Bernal, P. Delrot, D. Loterie, Y. Li, J. Malda, C. Moser, R. Levato
Publicado en: NBTE Annual Meeting, Issue 2019, 2019

Biofabrication approaches for cartilage repair.. Levato R. INSERM Bordeaux, France 2019

Autores: R. Levato
Publicado en: INSERM workshop, Issue 2019, 2019

Stimulating cartilage development of chondroprogenitor cells via GDF-2 supplementation in combination with melt electrowriting microfiber meshes.

Autores: Abinzano F, de Ruijter M, Mensinga A, Castilho M, Khan IM, Levato R, Malda J.
Publicado en: eCM XVIII: Cartilage & Disc: Repair and Regeneration,, Issue 2018, 2018

Effect of chondrocytes delivery strategy on cartilage repair evaluated in an ex vivo osteochondral plug.

Autores: Abinzano A, Mouser V, Dautzenberg N, van Rijen M, Dhert W, Levato R, Gawlitta D, Malda J.
Publicado en: 14th World Congress of the International Cartilage Repair Society, Issue 2018, 2018

A paradigm shift to accelerate endochondral bone regeneration.

Autores: Longoni A, Utomo L, Robinson A, Levato R, Rosenberg A, Gawlitta D.
Publicado en: 11th World Biomaterials Congress, Issue 2020, 2020

Growth Factor Immobilisation on Melt Electrowritten Fiber Scaffolds for Cartilage Tissue Engineering.

Autores: M. J. Ainsworth, O. Lotz, D. McKenzie, M. M. M. Bilek, J. Malda, B. Akhavan, M. Castilho.
Publicado en: RegMed XB Annual Meeting, Issue 2020, 2020

Design and fabrication of 3D printed magnesium phosphate-based scaffolds to repair large bone defects

Autores: Nasim Golafshan, Elke Vorndran, Stefan Zaharievski, Harold Brommer, Firoz Babu Kadumudi, Alireza Dolatshahi-Pirouz, Uwe Gbureck, René van Weeren, Miguel Castilho, and Jos Malda
Publicado en: RegMed XB Annual Meeting, Issue 2020, 2020

Multi-process 3D (bio) printing for bone tissue regeneration

Autores: Miguel Castilho
Publicado en: Bone Innovation Summit, Issue 2019, 2019

Multilayered Osteochondral Construct With Bioprinted Heterocellular Zonal-like Architecture.

Autores: Levato R, van den Dorpel B, Otto IA, Khan IM, van Weeren R, Malda J.
Publicado en: Orthopedics Research Society Annual Meeting, Issue 2018, 2018

Advanced tissue manufacturing strategies and applications in soft tissue repair

Autores: Miguel Castilho
Publicado en: TERMIS EU 2019, Issue 2019, 2019

Converging Melt Electrospinning Writing And Extrusion Based Bioprinting For Cartilage Tissue Engineering.

Autores: M. de Ruijter, A. Ribeiro, I. Dokter, M. Castilho, J. Malda
Publicado en: 29th European Conference on Biomaterials, Issue 2018, 2018

Obtaining Cartilage Extracellular Matrix: A Comparison Between Four Decellularization Methods.

Autores: M. L. Terpstra, C. H. A. van de Lest, R. Levato, J. Malda
Publicado en: European Society for Biomaterials (ESB), Issue 2019, 2019

Highly organized osteochondral implants, developing a multi-scale, single-step biofabrication process

Autores: de Ruijter M, Diloksumpan P, Dokter I, Levato R, Castilho M, Malda J.
Publicado en: BSRT symposium, the art of failure., Issue 2018, 2018

Orthotopic bone regeneration within 3D printed region-dependent porous bioceramic scaffolds in an equine model (NBTE)

Autores: P. Diloksumpan, R. Vindas Bolaños, S. Cokelaere, B. Pouran, J. de Grauw, M. van Rijen, P. R. van Weeren, R. Levato, J. Malda
Publicado en: NBTE Annual Meeting, Issue 2019, 2019

Manufacturing complex tissue analogs with multi-scale bioprinting technologies

Autores: Levato R.
Publicado en: eCM 2020 conference, Issue 2020, 2020

Interfacing hard and soft biomaterials for simultaneous regeneration of bone and cartilage

Autores: M. Castilho, S. Amin Yavari, B. Akhavan, P. Taheri, M.A. Leeflang, J.M.C. Mol, H. Weinans, M.M.M. Bilek, J. Malda, A.A. Zadpoor.
Publicado en: 5th TERMIS World Congres, Issue 2018, 2018

Combining melt electrowriting of microfiber meshes with aggregated chondroprogenitor cells stimulated with GDF-2 to enhance cartilage tissue engineering.

Autores:  Abinzano F, de Ruijter M, Mensinga A, Castilho M, Khan I, Levato R, Malda J
Publicado en: 29th European Conference on Biomaterials, Issue 2018, 2018

Multi-scale fabrication of an osteochondral implant with hierarchy in fiber orientation and cell distribution (TERMIS).

Autores: M. de Ruijter, Paweena Diloksumpan, Inge Dokter, Harold Brommer, Filipe M. Braganca, Riccardo Levato, P. René van Weeren, Miguel Castilho, Jos Malda.
Publicado en: TERMIS EU 2019, Issue 2019, 2019

Influence of 3D printed region-dependent pore architecture on orthotopic bone regeneration in an equine model

Autores: P. Diloksumpan, R. Vindas Bolaños, S. Cokelaere, B. Pouran, J. de Grauw, M. van Rijen, P. R. van Weeren, R. Levato, J. Malda
Publicado en: 11th World Biomaterials Congress, Issue 2020, 2020

Integration of hydrogel-based cartilage constructs on ceramic subchondral bone substitutes combining multiple 3D printing technologies

Autores: Diloksumpan P., Castilho M., Vermonden T. , Van Weeren PRR, Malda J. and Levato R
Publicado en: 5th TERMIS World Congress, Issue 2018, 2018

Integrating multiple biofabrication technologies to create complex and functional musculoskeletal tissue grafts.

Autores: Levato R.
Publicado en: 3D Printing in Life Sciences SelectBio conference, Issue 2019, 2019

Reinforcing hydrogel-to-ceramic interface in engineered osteochondral grafts by converging biofabrication techniques.

Autores: Diloksumpan P, Castilho M, Vermonden T, van Weeren R, Malda J, Levato R
Publicado en: 14th World Congress of the International Cartilage Repair Society, Issue 2018, 2018

Bi-functional Visible Light-Responsive Gelatin Bioglues for Cartilage Restoration

Autores: F. Abinzano, K. Lim, P. Núñez Bernal, P. Atienza Roca, A. Albillos Sánchez, I. A. Otto, T. Woodfield, J. Malda, R. Levato
Publicado en: NBTE Annual Meeting, Issue 2019, 2019

Bioprinting of zonal-like cartilage constructs using chondroprogenitor and mesenchymal stromal cells.

Autores: Levato R, Kahn IM, van Weeren R, Malda J
Publicado en: 14th World Congress of the International Cartilage Repair Society, Issue 2018, 2018

Computational design optimisation for local control over mechanical properties in heterogeneous scaffolds

Autores: C. Villette, M. Castilho, J Malda, A Phillips.
Publicado en: 15th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Issue 2018, 2018

3D printed tough magnesium phosphate-based implants induce bone regeneration in an equine defect model

Autores: N Golafshan1, E Vorndran2, M Braham, S Zaharievski, J Alblas, F Babu, A Dolatshahi-Pirouz, M Castilho, J Malda
Publicado en: 11th World Biomaterials Congress, Issue 2020, 2020

Comparing Four Decellularization Methods to Obtain Cartilage Extracellular Matrix

Autores: M. L. Terpstra, P.R. van Weeren, R. Levato, J. Malda.
Publicado en: NBTE, Issue 2018, 2018

High-speed volumetric bioprinting approach for biofabrication of complex living tissue structures.

Autores: P. N. Bernal, P. Delrot, D. Loterie, Y. Li, J. Malda, C. Moser, R. Levato
Publicado en: TERMIS-EU Chapter conference, Issue 2020, 2020

A Bone Substitute with High Bioactivity, strength, and Porosity for Repairing Large Bone Defects

Autores: Nasim Golafshan, EVorndran, M Braham, S Zaharievski, J Alblas, M Castilho, J Malda
Publicado en: European Society for Biomaterials (ESB), Issue 2019, 2019

Highly organized osteochondral implants, developing a multi-scale, single-step biofabrication process.

Autores: de Ruijter M, Diloksumpan P, Dokter I, Levato R, Castilho M, Malda J.
Publicado en: BSRT symposium, the art of failure., Issue 2018, 2018

Electrohydrodynamic Additive Manufacturing to Achieve the Next Generation of Functional Biomaterials (3DHRS)

Autores: Miguel Castilho
Publicado en: 3D BioPrinting in Healthcare Research Symposium, Issue 2019, 2019

One-step dual photocrosslinkable tyramine-enhanced bioglue for in situ tissue repair (poster presentation)

Autores: F Abinzano, K. Lim, P. Núñez Bernal, P. Atienza Roca, A. Albillos Sánchez, I. A. Otto, T. Woodfield, J. Malda, R. Levato
Publicado en: European Society for Biomaterials (ESB), Issue 2019, 2019

Engineered reinforced osteochondral plugs combining 3D printing, electrowriting and cartilage progenitor cells assembly.

Autores: Levato R, Abinzano F, Diloksumpan P, de Ruijter M, Castilho M, Khan I, van Weeren R, Malda J.
Publicado en: 15th ICRS World Congress, Issue 2019, 2019

Obtaining cartilage extracellular matrix: a comparison between four decellularization methods (NVMB)

Autores: M. L. Terpstra, C. H. A. van de Lest, R. Levato, J. Malda
Publicado en: NVMB Annual Meeting, Issue 2019, 2019

Progenitor cells in human auricular cartilage and microtia remnant produce neocartilage in 3D hydrogel culture

Autores:  Otto IA, Nunez-Bernal P, Levato R, Breugem C, Malda J.
Publicado en: 5th TERMIS World Congress, Issue 2018, 2018

Capturing the zonal mechanical properties of native cartilage with bi-layered microfibre reinforced hydrogels

Autores: Miguel Castilho, Vivian Mouser, Mike Chen, Jos Malda, Keita Ito
Publicado en: 25th Congress of the European Society of Biomechanics, Issue 2019, 2019

Towards the biofabrication of complex, heterogeneous bone and cartilage structures with multiple printing technologies.

Autores: Levato R.
Publicado en: TERMIS EU 2019, Issue 2019, 2019

Fabricatie van microvezels ter versterking van hydrogelen voor regeneratie van kraakbeen.

Autores: M. de Ruijter, A. Hrynevich, J.N. Haigh, M. Castilho, G. Hochleitner, J. Groll, J Malda, and P.D. Dalton
Publicado en: Nederlandse Orthopaedische Vereniging Jaarcongres, Issue 2017, 2017

Optimization of Heterogeneous Bone Tissue Engineering Scaffolds: Proof of Concept for a digital design tool.

Autores: C. Villete, M. Castilho, J. Malda, A. Philips
Publicado en: 23rd Congress of the European Society of Biomechanics, Issue 2017, 2017

Approach for standardized evaluation of printability and structural deformation of extruded bioink filaments.

Autores: M. Blokzijl, A. Ribeiro, C. Visser, R. Levato, M. Castilho, W. Hennink, T. Vermonden, J. Malda
Publicado en: TERMIS-EU Chapter Conference., Issue 2017, 2017

Hydrogel encapsulation and Micro-aggregation of co-culture MSC/AC for tissue regeneration.

Autores: M. de Ruijter, F.P.W Melchels, R. Levato, J. Malda
Publicado en: World Biomaterials Conference, Issue 2016, 2016

3D printing of osteoconductive patient-specific bone implants.

Autores: M. Castilho, C. Moseke, U.Gbureck, E. Vorndran
Publicado en: 28th Annual Conference of the European Society for Biomaterials, Issue 2017, 2017

 Fabricatie van microvezels ter versterking van hydrogelen voor regeneratie van kraakbeen.

Autores: M. de Ruijter, A. Hrynevich, J.N. Haigh, G. Hochleitner, M. Castilho, J. Malda, J. Groll, P.D. Dalton.
Publicado en: Nederlandse Orthopaedische Vereniging Jaarcongres, Issue 2017, 2017

Optimised heterogeneous scaffolds: towards tailored bone mechanotransduction.

Autores: C. Villete, M. Castilho, J. Malda, A. Philips
Publicado en: ECCOMAS Thematic Conference on Multiscale Problems in Biomechanics and Mechanobiology, Issue 2017, 2017

Reinforced gelatin hydrogels for cartilage repair: from in vitro testing to implantation in the equine knee joint.

Autores: J. Visser, F. Melchels, I. Mancini, H. Brommer, P.Dalton, W.r Dhert, D. Saris, D. Hutmacher, R. van Weeren, J. Malda
Publicado en: International Conference of Biofabrication, Issue 2015, 2015

Converging MEW and extrusion-based bioprinting enables further mimicking of complex tissue architectures.

Autores: M. de Ruijter, A. Ribeiro, I. Dokter, M. Castilho, J. Malda
Publicado en: Biofabrication, Issue 2017, 2017

Mechanical behaviour of soft hydrogels reinforced with printed microfiber scaffolds for cartilage repair.

Autores: M. Castilho, G. Hochleitner, W. Wilson, J. Groll, J. Malda, K. Ito
Publicado en: International Cartilage Repair Society, 13th World Congress, Issue 2016, 2016

The bio in the ink: zonal-competent progenitor cells in printed layered constructs for cartilage regeneration

Autores: R. Levato, W.R. Webb, I.A. Otto IA, V.H.M. Mouser, P.R. van Weeren, I.M. Khan, J. Malda
Publicado en: Biofabrication, Issue 2016, 2016

Converging of melt electrospinning writing and extrusion based bioprinting for cartilage tissue regeneration.

Autores: M. de Ruijter, A. Ribeiro, I. Dokter, M. Castilho, J. Malda
Publicado en: Nederlandse vereniging voor Biomaterialen en Tissue Engineering, Issue 2017, 2017

Reinforcing hydrogel-to-ceramic interface in osteochondral constructs by converging additive manufacturing techniques.

Autores: P. Diloksumpan, M. Castilho, T. Vermonden, R. van Weeren, J. Malda, R. Levato
Publicado en: Biofabrication, Issue 2017, 2017

Bioink development and role of cell-bioink interaction for the biofabrication.

Autores: R. Levato, V. Mouser, W. Dhert, D. Gawlitta, R. van Weeren, J. Malda
Publicado en: Biofabrication, Issue 2017, 2017

Melt electrospun fibers to improve shear properties

Autores: M. de Ruijter, A. Hrynevich, J.N. Haigh, M. Castilho, G. Hochleitner, J. Groll, J Malda, and P.D. Dalton
Publicado en: Biofabrication, Issue 2016, 2016

Melt electrospinning writing of poly-hydroxymethylglycolide-co-ε-caprolactone-based scaffolds for cardiac tissue engineering.

Autores: M. Castilho, D. Feyen, M. Flandes-Iparraguirre, G. Hochleitner, P. Dalton, J. Groll, T. Vermonden, J. Malda, J. Sluijter
Publicado en: Biofabrication, Issue 2016, 2016

A dual crosslinking strategy for reinforcing gelatine-methacrylamide hydrogels for tissue repair

Autores: F.P.W Melchels, K.E.C. Blokland, M. de Ruijter, J. Malda
Publicado en: World Biomaterials Conference, Issue 2016, 2016

Biofunctional and complex hydrogel architectures fabricated via visible light photo-crosslinking with digital light processing.

Autores: K.S. Lim, R. Levato, P.F. Costa, M.D. Castilho, K. van Dorenmalen, F.P.W. Melchel, D. Gawlitta, J. Malda , T.B.F. Woodfield
Publicado en: TERMIS - EU Chapter Conference, Issue 2016, 2016

Improving mechanical functioning of micro-fibre reinforced hydrogels for zonal articular cartilage repair.

Autores: M. Castilho, S. Kogelenberg, V. Mouser, J. Malda, K. Ito
Publicado en: Biofabrication, Issue 2017, 2017

Improving mechanical functioning of micro-fibre reinforced hydrogels for cartilage repair.

Autores: M. Castilho, S. van Kogelenberg, J. Malda, K. Ito
Publicado en: TERMIS-EU Chapter Conference, Issue 2017, 2017

Biofabrication of anatomically shaped implants for regeneration of the rabbit humeral head

Autores: J. Visser, R. J. Custers, P. D. Dalton, R. Nizak, D. B.F. Saris, D. Gawlitta, J. Malda
Publicado en: International Conference on Biofabrication, Issue 2015, 2015

3D-Microfibers improve the shear modulus of hydrogel composites.

Autores: M. de Ruijter, A. Hrynevich, J.N. Haigh, G. Hochleitner, M. Castilho, J. Malda
Publicado en: ECI - Biofabrication for Hierarchical in Vitro Tissue Models, Issue 2017, 2017

Application of different cell populations in hydrogel bioinks for zonal cartilage biofabrication.

Autores: R. Levato, I.A. Otto, W.R. Webb, R. Van Weeren, I.M. Khan, J. Malda
Publicado en: ECI Biofabrication of hierarchical in vitro tissue models, Issue 2017, 2017

Assessing bioink printability with accessible and quantitative methods.

Autores: A. Ribeiro, M. Blokzijl, R. Levato, M. Castilho, W. Hennink, T. Vermonden, J. Malda
Publicado en: ECI - Biofabrication for Hierarchical in Vitro Tissue Models, Issue 2017, 2017

Engineering MEW-Reinforced Hydrogels to Enhance the Mechanics of Cartilage Constructs

Autores: Galarraga J, Levato R, Peiffer Q, Castilho M, Malda J, Burdick J.
Publicado en: 11th World Biomaterials Congress, Issue 2020, 2020

Engineered bi-layered microfibre reinforced hydrogel for zonal cartilage repair

Autores: Miguel Castilho, Vivian Mouser, Mike Chen, Jos Malda, Keita Ito
Publicado en: International Conference on Biofabrication, Issue November 2019, 2019

Electrohydrodynamic Additive Manufacturing to Achieve the Next Generation of Functional Biomaterials

Autores: Miguel Castilho
Publicado en: Science for Life conference 2019, Issue 2019, 2019

Zonal constructs for cartilage repair; from in vitro development to long-term implantation in an equine model

Autores: I.A.D. Mancini, R. Levato, H. Brommer, B. Pouran, T. Boeck, F. Abinzano, A. Mensinga, M.H.P. van Rijen, T. Blunk, J. Groll, J. Malda, P.R. van Weeren,
Publicado en: 5th TERMIS World Congress, Issue 2018, 2018

Functionalized 3D printed micro fibre scaffolds to bridge the gap between tendon/ligament and bone tissues

Autores: M. Castilho, J. Crispim, C. Hagmeijer, P. Jonkehijm, D.B.F. Saris, J Malda
Publicado en: 5th TERMIS World Congress, Issue 2018, 2018

Converging of melt electrowriting and extrusion-based bioprinting for cartilage tissue regeneration

Autores: M. de Ruijter, A. Ribeiro, I. Dokter, M. Castilho, J. Malda. 
Publicado en: 14th World Congress of the International Cartilage Repair Society, Issue 2018, 2018

In vivo evaluatie van 3D geprinte osteochondrale implantaten voor kraakbeen regeneratie.

Autores: M. de Ruijter, Paweena Diloksumpan, Inge Dokter, Harold Brommer, Filipe M. Braganca, Riccardo Levato, P. René van Weeren, Miguel Castilho, Jos Malda
Publicado en: NOV Annual Meeting, Issue 2019, 2019

Cartilage tissue formation via stimulation of chondroprogenitor cell spheroids with GDF-2 and assembly within melt electro-written microfibrous meshes

Autores: F. Abinzano, M. de Ruijter, A. Mensinga, M. Castilho, I. Khan, R. Levato and J. Malda.
Publicado en: ISBF International Conference on Biofabrication, Issue 2018, 2018

Combining 3d-printing of a low-temperature setting calcium phosphate paste with melt electrowritten microfiber meshes for reinforcing interfaces in engineered osteochondral grafts.

Autores: Diloksumpan P, Castilho M, Vermonden T, van Weeren P, Malda J, Levato R.
Publicado en: 29th European Conference on Biomaterials,, Issue 2018, 2018

Osteochondral Plug: a multi-scale, single-step fabrication process

Autores: M. de Ruijter, Inge Dokter, Paweena Diloksumpan, Riccardo Levato, Miguel Castilho, Jos Malda.
Publicado en: Annual meeting of the International Society for Biofabrication, Issue 2018, 2018

Heterogeneous design optimisation of tissue engineering scaffolds: in-silico and in-vitro assessment

Autores: C. Villette, M. Castilho, J Malda, A Phillips. Heterogeneous design optimisation of tissue engineering scaffolds: in-silico and in-vitro assessment 8th World Congress of Biomechanics in Dublin, Ireland (2018)
Publicado en: 8th World Congress of Biomechanics, Issue 2018, 2018

Enhancing cartilage synthesis via GDF-2 stimulation for aggregated chondroprogenitor cells loaded in melt electrospun writing microfiber meshes.

Autores: Abinzano F, de Ruijter M, Mensinga A, Khan I, Levato R, Malda J.
Publicado en: 5th TERMIS World congress, Issue 2018, 2018

Cartilage Tissue Engineering Using Auricular Cartilage Progenitor Cells in a 3D Hydrogel System

Autores: I.A. Otto, R. Levato, W.R. Webb, I.M. Khan, C.C. Breugem, J. Malda.
Publicado en: ICRS Conference, Issue 2018, 2018

Cartilage Tissue Engineering by Combining GDF-2 Grown Articular Cartilage Progenitor Cells and Microfiber Meshes Fabricated via Melt Electrowriting

Autores: F. Abinzano, M. de Ruijter, A. Mensinga, M. Castilho, I. Khan, R. Levato and J. Malda
Publicado en: NBTE annual meeting, Issue 2018, 2018

Multi-scale fabrication of an osteochondral implant with hierarchy in fiber orientation and cell distribution.

Autores: M. de Ruijter, Paweena Diloksumpan, Inge Dokter, Harold Brommer, Filipe M. Braganca, Riccardo Levato, P. René van Weeren, Miguel Castilho, Jos Malda.
Publicado en: International Conference on Biofabrication, Issue 2019, 2019

Multi-scale fabrication of an osteochondral implant with hierarchy in fiber orientation and cell distribution (ICRS).

Autores: M. de Ruijter, Paweena Diloksumpan, Inge Dokter, Harold Brommer, Filipe M. Braganca, Riccardo Levato, P. René van Weeren, Miguel Castilho, Jos Malda.
Publicado en: 15th ICRS World Congress, Issue 2019, 2019

Converging of melt electrowriting and extrusion-based bioprinting for cartilage tissue regeneration applications

Autores: M. de Ruijter, A. Ribeiro, I. Dokter, M. Castilho, J. Malda. 
Publicado en: 5th TERMIS World Congress, Issue 2018, 2018

Bioresin for printing of cell-laden hydrogels with 3D convoluted vessel-like microfluidic channels via digital light processing

Autores: Levato R, Lim K, Gawlitta D, Woodfield T, Malda J.
Publicado en: 29th European Conference on Biomaterials, Issue 2018, 2018

In vivo evaluation of 3D bioprinted osteochondral implants with hierarchical fiber orientation and cellular distribution.

Autores: de Ruijter M, Diloksumpan P, Dokter I, Brommer H, Braganca F, Levato R, van Weeren R, Castilho M, Malda J.
Publicado en: 11th World Biomaterials Congress, Issue 2020, 2020

The Use Of Converging Biofabrication Techniques To Address Nature's Complexity In Joint Repair

Autores: Paweena Diloksumpan
Publicado en: 2020

Diarthrodial joint resurfacing: Multi-scale biofabrication of mechanically stable implants.Osteochondral tissue regeneration in the knee joint

Autores: Mylène de Ruijter promotor: prof. dr. ir. Jos Malda co-promotor: dr. ir. Miguel Castilho
Publicado en: 2020

Multiscale modelling and homogenisation of fibre-reinforced hydrogels for tissue engineering

Autores: M. J. CHEN, L. S. KIMPTON, J. P. WHITELEY, M. CASTILHO, J. MALDA, C. P. PLEASE, S. L. WATERS, H. M. BYRNE
Publicado en: European Journal of Applied Mathematics, Issue 31/1, 2020, Page(s) 143-171, ISSN 0956-7925
DOI: 10.1017/s0956792518000657

Biofabrication of reinforced 3D-scaffolds using two-component hydrogels

Autores: Kristel W. M. Boere, Maarten M. Blokzijl, Jetze Visser, J. Elder A. Linssen, Jos Malda, Wim E. Hennink, Tina Vermonden
Publicado en: Journal of Materials Chemistry B, Issue 3/46, 2015, Page(s) 9067-9078, ISSN 2050-7518
DOI: 10.1039/c5tb01645b

Gelatin-Methacryloyl Hydrogels: Towards Biofabrication-Based Tissue Repair

Autores: Barbara J. Klotz, Debby Gawlitta, Antoine J.W.P. Rosenberg, Jos Malda, Ferry P.W. Melchels
Publicado en: Trends in Biotechnology, Issue 34/5, 2016, Page(s) 394-407, ISSN 0167-7799
DOI: 10.1016/j.tibtech.2016.01.002

Yield stress determines bioprintability of hydrogels based on gelatin-methacryloyl and gellan gum for cartilage bioprinting

Autores: Vivian H M Mouser, Ferry P W Melchels, Jetze Visser, Wouter J A Dhert, Debby Gawlitta, Jos Malda
Publicado en: Biofabrication, Issue 8/3, 2016, Page(s) 035003, ISSN 1758-5090
DOI: 10.1088/1758-5090/8/3/035003

Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data

Autores: Pedro F. Costa, Hugo J. Albers, John E. A. Linssen, Heleen H. T. Middelkamp, Linda van der Hout, Robert Passier, Albert van den Berg, Jos Malda, Andries D. van der Meer
Publicado en: Lab Chip, Issue 17/16, 2017, Page(s) 2785-2792, ISSN 1473-0197
DOI: 10.1039/c7lc00202e

Development of a thermosensitive HAMA-containing bio-ink for the fabrication of composite cartilage repair constructs

Autores: V H M Mouser, A Abbadessa, R Levato, W E Hennink, T Vermonden, D Gawlitta, J Malda
Publicado en: Biofabrication, Issue 9/1, 2017, Page(s) 015026, ISSN 1758-5090
DOI: 10.1088/1758-5090/aa6265

A Synthetic Thermosensitive Hydrogel for Cartilage Bioprinting and Its Biofunctionalization with Polysaccharides

Autores: Anna Abbadessa, Vivian H. M. Mouser, Maarten M. Blokzijl, Debby Gawlitta, Wouter J. A. Dhert, Wim E. Hennink, Jos Malda, Tina Vermonden
Publicado en: Biomacromolecules, Issue 17/6, 2016, Page(s) 2137-2147, ISSN 1525-7797
DOI: 10.1021/acs.biomac.6b00366

Hydrogel-based reinforcement of 3D bioprinted constructs

Autores: Ferry P W Melchels, Maarten M Blokzijl, Riccardo Levato, Quentin C Peiffer, Mylène de Ruijter, Wim E Hennink, Tina Vermonden, Jos Malda
Publicado en: Biofabrication, Issue 8/3, 2016, Page(s) 035004, ISSN 1758-5090
DOI: 10.1088/1758-5090/8/3/035004

From intricate to integrated: Biofabrication of articulating joints

Autores: Wilhelmina Margaretha Groen, Paweena Diloksumpan, Paul René van Weeren, Riccardo Levato, Jos Malda
Publicado en: Journal of Orthopaedic Research, Issue 35/10, 2017, Page(s) 2089-2097, ISSN 0736-0266
DOI: 10.1002/jor.23602

A thermo-responsive and photo-polymerizable chondroitin sulfate-based hydrogel for 3D printing applications

Autores: A. Abbadessa, M.M. Blokzijl, V.H.M. Mouser, P. Marica, J. Malda, W.E. Hennink, T. Vermonden
Publicado en: Carbohydrate Polymers, Issue 149, 2016, Page(s) 163-174, ISSN 0144-8617
DOI: 10.1016/j.carbpol.2016.04.080

Extracellular vesicles — new tool for joint repair and regeneration

Autores: Jos Malda, Janneke Boere, Chris H. A. van de Lest, P. René van Weeren, Marca H. M. Wauben
Publicado en: Nature Reviews Rheumatology, Issue 12/4, 2016, Page(s) 243-249, ISSN 1759-4790
DOI: 10.1038/nrrheum.2015.170

Out-of-Plane 3D-Printed Microfibers Improve the Shear Properties of Hydrogel Composites

Autores: Mylène de Ruijter, Andrei Hrynevich, Jodie N. Haigh, Gernot Hochleitner, Miguel Castilho, Jürgen Groll, Jos Malda, Paul D. Dalton
Publicado en: Small, 2017, Page(s) 1702773, ISSN 1613-6810
DOI: 10.1002/smll.201702773

Combining regenerative medicine strategies to provide durable reconstructive options: auricular cartilage tissue engineering

Autores: Zita M. Jessop, Muhammad Javed, Iris A. Otto, Emman J. Combellack, Siân Morgan, Corstiaan C. Breugem, Charles W. Archer, Ilyas M. Khan, William C. Lineaweaver, Moshe Kon, Jos Malda, Iain S. Whitaker
Publicado en: Stem Cell Research & Therapy, Issue 7/1, 2016, Page(s) 7/19, ISSN 1757-6512
DOI: 10.1186/s13287-015-0273-0

The use of a cartilage decellularized matrix scaffold for the repair of osteochondral defects: the importance of long-term studies in a large animal model

Autores: R.A. Vindas Bolaños, S.M. Cokelaere, J.M. Estrada McDermott, K.E.M. Benders, U. Gbureck, S.G.M. Plomp, H. Weinans, J. Groll, P.R. van Weeren, J. Malda
Publicado en: Osteoarthritis and Cartilage, Issue 25/3, 2017, Page(s) 413-420, ISSN 1063-4584
DOI: 10.1016/j.joca.2016.08.005

Mechanical behavior of a soft hydrogel reinforced with three-dimensional printed microfibre scaffolds

Autores: Miguel Castilho, Gernot Hochleitner, Wouter Wilson, Bert van Rietbergen, Paul D. Dalton, Jürgen Groll, Jos Malda, Keita Ito
Publicado en: Scientific Reports, Issue 8/1, 2018, Page(s) 1245, ISSN 2045-2322
DOI: 10.1038/s41598-018-19502-y

Melt Electrospinning Writing of Poly-Hydroxymethylglycolide- co -ε-Caprolactone-Based Scaffolds for Cardiac Tissue Engineering

Autores: Miguel Castilho, Dries Feyen, María Flandes-Iparraguirre, Gernot Hochleitner, Jürgen Groll, Pieter A. F. Doevendans, Tina Vermonden, Keita Ito, Joost P. G. Sluijter, Jos Malda
Publicado en: Advanced Healthcare Materials, Issue 6/18, 2017, Page(s) 1700311, ISSN 2192-2640
DOI: 10.1002/adhm.201700311

Ethical considerations in the translation of regenerative biofabrication technologies into clinic and society

Autores: I A Otto, C C Breugem, J Malda, A L Bredenoord
Publicado en: Biofabrication, Issue 8/4, 2016, Page(s) 042001, ISSN 1758-5090
DOI: 10.1088/1758-5090/8/4/042001

Assessing bioink shape fidelity to aid material development in 3D bioprinting

Autores: A Ribeiro, M M Blokzijl, R Levato, C W Visser, M Castilho, W E Hennink, T Vermonden, J Malda
Publicado en: Biofabrication, Issue 10/1, 2018, Page(s) 014102, ISSN 1758-5090
DOI: 10.1088/1758-5090/aa90e2

Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration

Autores: Vivian H. M. Mouser, Riccardo Levato, Lawrence J. Bonassar, Darryl D. D’Lima, Daniel A. Grande, Travis J. Klein, Daniel B. F. Saris, Marcy Zenobi-Wong, Debby Gawlitta, Jos Malda
Publicado en: CARTILAGE, Issue 8/4, 2016, Page(s) 327-340, ISSN 1947-6035
DOI: 10.1177/1947603516665445

Fixation of Hydrogel Constructs for Cartilage Repair in the Equine Model: A Challenging Issue

Autores: Irina A.D. Mancini, Rafael A. Vindas Bolaños, Harold Brommer, Miguel Castilho, Alexandro Ribeiro, Johannes P.A.M. van Loon, Anneloes Mensinga, Mattie H.P. van Rijen, Jos Malda, René van Weeren
Publicado en: Tissue Engineering Part C: Methods, Issue 23/11, 2017, Page(s) 804-814, ISSN 1937-3384
DOI: 10.1089/ten.TEC.2017.0200

A Step Towards Clinical Translation of Biofabrication

Autores: Jos Malda, Jürgen Groll
Publicado en: Trends in Biotechnology, Issue 34/5, 2016, Page(s) 356-357, ISSN 0167-7799
DOI: 10.1016/j.tibtech.2016.03.003

Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering?

Autores: Kerstin Schneeberger, Bart Spee, Pedro Costa, Norman Sachs, Hans Clevers, Jos Malda
Publicado en: Biofabrication, Issue 9/1, 2017, Page(s) 013001, ISSN 1758-5090
DOI: 10.1088/1758-5090/aa6121

The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells

Autores: Riccardo Levato, William R. Webb, Iris A. Otto, Anneloes Mensinga, Yadan Zhang, Mattie van Rijen, René van Weeren, Ilyas M. Khan, Jos Malda
Publicado en: Acta Biomaterialia, Issue 61, 2017, Page(s) 41-53, ISSN 1742-7061
DOI: 10.1016/j.actbio.2017.08.005

Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration

Autores: Miguel Castilho, Vivian Mouser, Mike Chen, Jos Malda, Keita Ito
Publicado en: Acta Biomaterialia, Issue 95, 2019, Page(s) 297-306, ISSN 1742-7061
DOI: 10.1016/j.actbio.2019.06.030

Rethinking articular cartilage regeneration based on a 250-year-old statement

Autores: Jos Malda, Jürgen Groll, P. René van Weeren
Publicado en: Nature Reviews Rheumatology, Issue 15/10, 2019, Page(s) 571-572, ISSN 1759-4790
DOI: 10.1038/s41584-019-0278-7

A Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues

Autores: Barbara J. Klotz, Loes A. Oosterhoff, Lizette Utomo, Khoon S. Lim, Queralt Vallmajo‐Martin, Hans Clevers, Tim B. F. Woodfield, Antoine J. W. P. Rosenberg, Jos Malda, Martin Ehrbar, Bart Spee, Debby Gawlitta
Publicado en: Advanced Healthcare Materials, Issue 8/19, 2019, Page(s) 1900979, ISSN 2192-2640
DOI: 10.1002/adhm.201900979

Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species

Autores: I.A.D. Mancini, L. Rieppo, B. Pouran, I.O. Afara, F.M. Serra Braganca, M.H.P. van Rijen, M. Kik, H. Weinans, J. Toyras, P.R. van Weeren, J. Malda
Publicado en: Bone, Issue 127, 2019, Page(s) 664-673, ISSN 8756-3282
DOI: 10.1016/j.bone.2019.07.001

A definition of bioinks and their distinction from biomaterial inks

Autores: J Groll, J A Burdick, D-W Cho, B Derby, M Gelinsky, S C Heilshorn, T Jüngst, J Malda, V A Mironov, K Nakayama, A Ovsianikov, W Sun, S Takeuchi, J J Yoo, T B F Woodfield
Publicado en: Biofabrication, Issue 11/1, 2019, Page(s) 013001, ISSN 1758-5090
DOI: 10.1088/1758-5090/aaec52

Extracellular Vesicles in Joint Disease and Therapy

Autores: Janneke Boere, Jos Malda, Chris H. A. van de Lest, P. René van Weeren, Marca H. M. Wauben
Publicado en: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.02575

Biofabrication: A Guide to Technology and Terminology

Autores: Lorenzo Moroni, Thomas Boland, Jason A. Burdick, Carmelo De Maria, Brian Derby, Gabor Forgacs, Jürgen Groll, Qing Li, Jos Malda, Vladimir A. Mironov, Carlos Mota, Makoto Nakamura, Wenmiao Shu, Shoji Takeuchi, Tim B.F. Woodfield, Tao Xu, James J. Yoo, Giovanni Vozzi
Publicado en: Trends in Biotechnology, Issue 36/4, 2018, Page(s) 384-402, ISSN 0167-7799
DOI: 10.1016/j.tibtech.2017.10.015

Ex vivo model unravelling cell distribution effect in hydrogels for cartilage repair

Autores: Vivian Mouser
Publicado en: ALTEX, 2018, Page(s) 65-76, ISSN 1868-596X
DOI: 10.14573/altex.1704171

Extracellular vesicles in synovial fluid from juvenile horses: No age-related changes in the quantitative profile

Autores: J. Boere, C.H.A. van de Lest, J.C. de Grauw, S.G.M. Plomp, S.F.W.M. Libregts, G.J.A. Arkesteijn, J. Malda, M.H.M. Wauben, P.R. van Weeren
Publicado en: The Veterinary Journal, Issue 244, 2019, Page(s) 91-93, ISSN 1090-0233
DOI: 10.1016/j.tvjl.2018.12.010

Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds

Autores: Katja Jansen, Miguel Castilho, Sanne Aarts, Michael M. Kaminski, Soeren S. Lienkamp, Roman Pichler, Jos Malda, Tina Vermonden, Jitske Jansen, Rosalinde Masereeuw
Publicado en: Macromolecular Bioscience, Issue 19/2, 2018, Page(s) 1800412, ISSN 1616-5187
DOI: 10.1002/mabi.201800412

Simultaneous Micropatterning of Fibrous Meshes and Bioinks for the Fabrication of Living Tissue Constructs

Autores: Mylène de Ruijter, Alexandre Ribeiro, Inge Dokter, Miguel Castilho, Jos Malda
Publicado en: Advanced Healthcare Materials, Issue 8/7, 2019, Page(s) 1800418, ISSN 2192-2640
DOI: 10.1002/adhm.201800418

Arthroscopic near infrared spectroscopy enables simultaneous quantitative evaluation of articular cartilage and subchondral bone in vivo

Autores: Jaakko K. Sarin, Nikae C. R. te Moller, Irina A. D. Mancini, Harold Brommer, Jetze Visser, Jos Malda, P. René van Weeren, Isaac O. Afara, Juha Töyräs
Publicado en: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-31670-5

Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers

Autores: Marcia de Almeida Monteiro Melo Ferraz, Heiko H. W. Henning, Pedro Ferreira da Costa, Jos Malda, Séverine Le Gac, Fabrice Bray, Majorie B. M. van Duursen, Jos F. Brouwers, Chris H. A. van de Lest, Ingeborg Bertijn, Lisa Kraneburg, Peter L. A. M. Vos, Tom A. E. Stout, Barend M. Gadella
Publicado en: Environmental Science & Technology Letters, Issue 5/2, 2018, Page(s) 80-85, ISSN 2328-8930
DOI: 10.1021/acs.estlett.7b00495

Fiber Scaffold Patterning for Mending Hearts: 3D Organization Bringing the Next Step

Autores: Marleen Kristen, Madison J. Ainsworth, Nino Chirico, Casper F. T. Ven, Pieter A. Doevendans, Joost P. G. Sluijter, Jos Malda, Alain Mil, Miguel Castilho
Publicado en: Advanced Healthcare Materials, 2019, Page(s) 1900775, ISSN 2192-2640
DOI: 10.1002/adhm.201900775

Volumetric Bioprinting of Complex Living‐Tissue Constructs within Seconds

Autores: Paulina Nuñez Bernal, Paul Delrot, Damien Loterie, Yang Li, Jos Malda, Christophe Moser, Riccardo Levato
Publicado en: Advanced Materials, Issue 31/42, 2019, Page(s) 1904209, ISSN 0935-9648
DOI: 10.1002/adma.201904209

From Shape to Function: The Next Step in Bioprinting

Autores: Riccardo Levato, Tomasz Jungst, Ruben G. Scheuring, Torsten Blunk, Juergen Groll, Jos Malda
Publicado en: Advanced Materials, Issue 32/12, 2020, Page(s) 1906423, ISSN 0935-9648
DOI: 10.1002/adma.201906423

Combining multi-scale 3D printing technologies to engineer reinforced hydrogel-ceramic interfaces

Autores: Paweena Diloksumpan, Mylène de Ruijter, Miguel Castilho, Uwe Gbureck, Tina Vermonden, P René van Weeren, Jos Malda, Riccardo Levato
Publicado en: Biofabrication, Issue 12/2, 2020, Page(s) 025014, ISSN 1758-5090
DOI: 10.1088/1758-5090/ab69d9

One‐Step Photoactivation of a Dual‐Functionalized Bioink as Cell Carrier and Cartilage‐Binding Glue for Chondral Regeneration

Autores: Khoon S. Lim, Florencia Abinzano, Paulina Nuñez Bernal, Ane Albillos Sanchez, Pau Atienza‐Roca, Iris A. Otto, Quentin C. Peiffer, Michiya Matsusaki, Tim B. F. Woodfield, Jos Malda, Riccardo Levato
Publicado en: Advanced Healthcare Materials, 2020, Page(s) 1901792, ISSN 2192-2640
DOI: 10.1002/adhm.201901792

Orthotopic Bone Regeneration within 3D Printed Bioceramic Scaffolds with Region‐Dependent Porosity Gradients in an Equine Model

Autores: Paweena Diloksumpan, Rafael Vindas Bolaños, Stefan Cokelaere, Behdad Pouran, Janny Grauw, Mattie Rijen, René Weeren, Riccardo Levato, Jos Malda
Publicado en: Advanced Healthcare Materials, Issue 9/10, 2020, Page(s) 1901807, ISSN 2192-2640
DOI: 10.1002/adhm.201901807

Melt electrowriting onto anatomically relevant biodegradable substrates: Resurfacing a diarthrodial joint

Autores: Quentin C. Peiffer, Mylène de Ruijter, Joost van Duijn, Denis Crottet, Ernst Dominic, Jos Malda, Miguel Castilho
Publicado en: Materials & Design, Issue 195, 2020, Page(s) 109025, ISSN 0264-1275
DOI: 10.1016/j.matdes.2020.109025

Tough magnesium phosphate-based 3D-printed implants induce bone regeneration in an equine defect model

Autores: Nasim Golafshan, Elke Vorndran, Stefan Zaharievski, Harold Brommer, Firoz Babu Kadumudi, Alireza Dolatshahi-Pirouz, Uwe Gbureck, René van Weeren, Miguel Castilho, Jos Malda
Publicado en: Biomaterials, 2020, Page(s) 120302, ISSN 0142-9612
DOI: 10.1016/j.biomaterials.2020.120302

Joint endeavours

Autores: his piece was produced by Science Impact
Publicado en: 2017