Laser-induced vapour nanobubbles for intracellular delivery of nanomaterials and treatment of biofilm infections

Publicaciones

Bypassing Border Control: Nuclear Envelope Rupture in Disease

Autores: Gaëlle Houthaeve, Joke Robijns, Kevin Braeckmans, Winnok H. De Vos
Publicado en: Physiology, Edición 33/1, 2018, Página(s) 39-49, ISSN 1548-9213
Editor: American Physiological Society
DOI: 10.1152/physiol.00029.2017

Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells

Autores: Aranit Harizaj, Benedicte Descamps, Christophe Mangodt, Stephan Stremersch, Arianna Stoppa, Lieve Balcaen, Toon Brans, Hilde De Rooster, Nausikaa Devriendt, Juan C. Fraire, Eduardo Bolea-Fernandez, Olivier De Wever, Wouter Willaert, Frank Vanhaecke, Christian V. Stevens, Stefaan C. De Smedt, Bart Roman, Christian Vanhove, Ine Lentacker, Kevin Braeckmans
Publicado en: Biomaterials Science, Edición 9/11, 2021, Página(s) 4005-4018, ISSN 2047-4830
Editor: Royal Society of Chemistry
DOI: 10.1039/d1bm00479d

Surface Functionalization with Polyethylene Glycol and Polyethyleneimine Improves the Performance of Graphene-Based Materials for Safe and Efficient Intracellular Delivery by Laser-Induced Photoporation

Autores: Jing Liu, Chengnan Li, Toon Brans, Aranit Harizaj, Shana Van de Steene, Thomas De Beer, Stefaan De Smedt, Sabine Szunerits, Rabah Boukherroub, Ranhua Xiong, Kevin Braeckmans
Publicado en: International Journal of Molecular Sciences, Edición 21/4, 2020, Página(s) 1540, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21041540

Exploring Light-Sensitive Nanocarriers for Simultaneous Triggered Antibiotic Release and Disruption of Biofilms Upon Generation of Laser-Induced Vapor Nanobubbles

Autores: Eline Teirlinck, Alexandre Barras, Jing Liu, Juan C. Fraire, Tatu Lajunen, Ranhua Xiong, Katrien Forier, Chengnan Li, Arto Urtti, Rabah Boukherroub, Sabine Szunerits, Stefaan C. De Smedt, Tom Coenye, Kevin Braeckmans
Publicado en: Pharmaceutics, Edición 11/5, 2019, Página(s) 201, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11050201

Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care

Autores: E. Teirlinck, J.C. Fraire, H. Van Acker, J. Wille, R. Swimberghe, T. Brans, R. Xiong, M. Meire, R.J.G. De Moor, S.C. De Smedt, T. Coenye, K. Braeckmans
Publicado en: Biofilm, Edición 1, 2019, Página(s) 100004, ISSN 2590-2075
Editor: Elsevier
DOI: 10.1016/j.bioflm.2019.100004

Intracellular Labeling with Extrinsic Probes: Delivery Strategies and Applications

Autores: Jing Liu, Juan C. Fraire, Stefaan C. De Smedt, Ranhua Xiong, Kevin Braeckmans
Publicado en: Small, Edición 16/22, 2020, Página(s) 2000146, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202000146

Gold Nanoparticle-Mediated Photoporation Enables Delivery of Macromolecules over a Wide Range of Molecular Weights in Human CD4+ T Cells

Autores: Laurens Raes, Clarissa Van Hecke, Julie Michiels, Stephan Stremersch, Juan C. Fraire, Toon Brans, Ranhua Xiong, Stefaan De Smedt, Linos Vandekerckhove, Koen Raemdonck, Kevin Braeckmans
Publicado en: Crystals, Edición 9/8, 2019, Página(s) 411, ISSN 2073-4352
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cryst9080411

Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells

Autores: Aranit Harizaj, Filip Van Hauwermeiren, Stephan Stremersch, Riet De Rycke, Herlinde De Keersmaecker, Toon Brans, Juan C. Fraire, Karolien Grauwen, Stefaan C. De Smedt, Ine Lentacker, Mohamed Lamkanfi, Kevin Braeckmans
Publicado en: Nanoscale, Edición 13/13, 2021, Página(s) 6592-6604, ISSN 2040-3364
Editor: Royal Society of Chemistry
DOI: 10.1039/d0nr05067a

Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells

Autores: Lien Van Hoecke, Laurens Raes, Stephan Stremersch, Toon Brans, Juan C. Fraire, Ria Roelandt, Wim Declercq, Peter Vandenabeele, Koen Raemdonck, Kevin Braeckmans, Xavier Saelens
Publicado en: International Journal of Molecular Sciences, Edición 20/17, 2019, Página(s) 4254, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20174254

Comparing photoporation and nucleofection for delivery of small interfering RNA to cytotoxic T cells

Autores: Laura Wayteck, Ranhua Xiong, Kevin Braeckmans, Stefaan C. De Smedt, Koen Raemdonck
Publicado en: Journal of Controlled Release, Edición 267, 2017, Página(s) 154-162, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2017.08.002

Fast spatial-selective delivery into live cells

Autores: Ranhua Xiong, Claire Drullion, Peter Verstraelen, Jo Demeester, Andre G. Skirtach, Corinne Abbadie, Winnok H. De Vos, Stefaan C. De Smedt, Kevin Braeckmans
Publicado en: Journal of Controlled Release, Edición 266, 2017, Página(s) 198-204, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/J.JCONREL.2017.09.033

Selective Labeling of Individual Neurons in Dense Cultured Networks With Nanoparticle-Enhanced Photoporation

Autores: Ranhua Xiong, Peter Verstraelen, Jo Demeester, Andre G. Skirtach, Jean-Pierre Timmermans, Stefaan C. De Smedt, Winnok H. De Vos, Kevin Braeckmans
Publicado en: Frontiers in Cellular Neuroscience, Edición 12, 2018, Página(s) Article 80, ISSN 1662-5102
Editor: Frontiers Research Foundation
DOI: 10.3389/fncel.2018.00080

Photothermally Triggered Endosomal Escape and Its Influence on Transfection Efficiency of Gold-Functionalized JetPEI/pDNA Nanoparticles

Autores: Lotte Vermeulen, Juan Fraire, Laurens Raes, Ellen De Meester, Sarah De Keulenaer, Filip Van Nieuwerburgh, Stefaan De Smedt, Katrien Remaut, Kevin Braeckmans
Publicado en: International Journal of Molecular Sciences, Edición 19/8, 2018, Página(s) 2400, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms19082400

Cytosolic Delivery of Nanolabels Prevents Their Asymmetric Inheritance and Enables Extended Quantitative in Vivo Cell Imaging

Autores: Ranhua Xiong, Freya Joris, Sayuan Liang, Riet De Rycke, Saskia Lippens, Jo Demeester, Andre Skirtach, Koen Raemdonck, Uwe Himmelreich, Stefaan C. De Smedt, Kevin Braeckmans
Publicado en: Nano Letters, Edición 16/10, 2016, Página(s) 5975-5986, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.6b01411

Laser-assisted photoporation: fundamentals, technological advances and applications

Autores: Ranhua Xiong, Sangram Keshari Samal, Jo Demeester, Andre G. Skirtach, Stefaan C. De Smedt, Kevin Braeckmans
Publicado en: Advances in Physics: X, Edición 1/4, 2016, Página(s) 596-620, ISSN 2374-6149
Editor: Taylor & Francis Online
DOI: 10.1080/23746149.2016.1228476

Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability

Autores: Ranhua Xiong, Roosmarijn E. Vandenbroucke, Katleen Broos, Toon Brans, Elien Van Wonterghem, Claude Libert, Jo Demeester, Stefaan C. De Smedt, Kevin Braeckmans
Publicado en: Nature Communications, Edición 7, 2016, Página(s) 12982, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/ncomms12982

Targeted Perturbation of Nuclear Envelope Integrity with Vapor Nanobubble-Mediated Photoporation

Autores: Gaëlle Houthaeve, Ranhua Xiong, Joke Robijns, Bert Luyckx, Yasmine Beulque, Toon Brans, Coen Campsteijn, Sangram K. Samal, Stephan Stremersch, Stefaan C. De Smedt, Kevin Braeckmans, Winnok H. De Vos
Publicado en: ACS Nano, Edición 12/8, 2018, Página(s) 7791-7802, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.8b01860

Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation

Autores: Jing Liu, Tim Hebbrecht, Toon Brans, Eef Parthoens, Saskia Lippens, Chengnan Li, Herlinde De Keersmaecker, Winnok H. De Vos, Stefaan C. De Smedt, Rabah Boukherroub, Jan Gettemans, Ranhua Xiong, Kevin Braeckmans
Publicado en: Nano Research, Edición 13/2, 2020, Página(s) 485-495, ISSN 1998-0124
Editor: Tsinghua Univ Press
DOI: 10.1007/s12274-020-2633-z

Repeated photoporation with graphene quantum dots enables homogeneous labeling of live cells with extrinsic markers for fluorescence microscopy

Autores: Jing Liu, Ranhua Xiong, Toon Brans, Saskia Lippens, Eef Parthoens, Francesca Cella Zanacchi, Raffaella Magrassi, Santosh K. Singh, Sreekumar Kurungot, Sabine Szunerits, Hannelore Bové, Marcel Ameloot, Juan C. Fraire, Eline Teirlinck, Sangram Keshari Samal, Riet De Rycke, Gaëlle Houthaeve, Stefaan C. De Smedt, Rabah Boukherroub, Kevin Braeckmans
Publicado en: Light: Science & Applications, Edición 7/1, 2018, ISSN 2047-7538
Editor: Springer Nature
DOI: 10.1038/s41377-018-0048-3

Non-viral transfection technologies for next-generation therapeutic T cell engineering

Autores: Laurens Raes, Stefaan C. De Smedt, Koen Raemdonck, Kevin Braeckmans
Publicado en: Biotechnology Advances, Edición 49, 2021, Página(s) 107760, ISSN 0734-9750
Editor: Elsevier BV
DOI: 10.1016/j.biotechadv.2021.107760

Physical transfection technologies for macrophages and dendritic cells in immunotherapy

Autores: Aranit Harizaj, Stefaan C. De Smedt, Ine Lentacker, Kevin Braeckmans
Publicado en: Expert Opinion on Drug Delivery, Edición 18/2, 2021, Página(s) 229-247, ISSN 1742-5247
Editor: Ashley Publications Ltd.
DOI: 10.1080/17425247.2021.1828340

Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms

Autores: Eline Teirlinck, Ranhua Xiong, Toon Brans, Katrien Forier, Juan Fraire, Heleen Van Acker, Nele Matthijs, Riet De Rycke, Stefaan C. De Smedt, Tom Coenye, Kevin Braeckmans
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-06884-w

Stimuli-responsive nanobubbles for biomedical applications

Autores: Ranhua Xiong, Ronald X. Xu, Chaobo Huang, Stefaan De Smedt, Kevin Braeckmans
Publicado en: Chemical Society Reviews, Edición 50/9, 2021, Página(s) 5746-5776, ISSN 0306-0012
Editor: Royal Society of Chemistry
DOI: 10.1039/c9cs00839j

Derechos de propiedad intelectual

Carbon-based particles for vapour bubble generation

Número de solicitud/publicación: PCT/EP2016/ 065075
Fecha: 2016-06-29

Carbon-based particles for vapour bubble generation

Número de solicitud/publicación: PCT/EP2016/ 065075
Fecha: 2016-06-29

Carbon-based particles for vapour bubble generation

Número de solicitud/publicación: PCT/EP2016/ 065075
Fecha: 2016-06-29

Disruption or alteration of microbiological films

Número de solicitud/publicación: PCT/EP2016/ 065073
Fecha: 2016-06-29

Disruption or alteration of microbiological films

Número de solicitud/publicación: PCT/EP2016/ 065073
Fecha: 2016-06-29

Disruption or alteration of microbiological films

Número de solicitud/publicación: PCT/EP2016/ 065073
Fecha: 2016-06-29

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Publicaciones

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