Regulating the immune regulators: targeting adaptive immune control

Project Information

REGiREG

Grant agreement ID: 648145

DOI

10.3030/648145

Project closed

EC signature date 9 June 2015

Start date 1 July 2015

End date 30 June 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 955 000,00

EU contribution

€ 1 955 000,00

Coordinated by

KLINIKUM DER UNIVERSITAET REGENSBURG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells

Author(s): Michael Delacher, Melanie M. Barra, Yonatan Herzig, Katrin Eichelbaum, Mahmoud-Reza Rafiee, David M. Richards, Ulrike Träger, Ann-Cathrin Hofer, Alexander Kazakov, Kathrin L. Braband, Marina Gonzalez, Lukas Wöhrl, Kathrin Schambeck, Charles D. Imbusch, Jakub Abramson, Jeroen Krijgsveld, Markus Feuerer
Published in: iScience, Issue 23/5, 2020, Page(s) 101127, ISSN 2589-0042
Publisher: ELSEVIER
DOI: 10.1016/j.isci.2020.101127

Re-examining the Nature and Function of Self-Reactive T cells

Author(s): David M. Richards, Bruno Kyewski, Markus Feuerer
Published in: Trends in Immunology, Issue 37/2, 2016, Page(s) 114-125, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2015.12.005

Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues

Author(s): Michael Delacher, Charles D Imbusch, Dieter Weichenhan, Achim Breiling, Agnes Hotz-Wagenblatt, Ulrike Träger, Ann-Cathrin Hofer, Danny Kägebein, Qi Wang, Felix Frauhammer, Jan-Philipp Mallm, Katharina Bauer, Carl Herrmann, Philipp A Lang, Benedikt Brors, Christoph Plass, Markus Feuerer
Published in: Nature Immunology, Issue 18/10, 2017, Page(s) 1160-1172, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/ni.3799

Rbpj expression in regulatory T cells is critical for restraining TH2 responses

Author(s): Michael Delacher, Christian Schmidl, Yonatan Herzig, Minka Breloer, Wiebke Hartmann, Fabian Brunk, Danny Kägebein, Ulrike Träger, Ann-Cathrin Hofer, Sebastian Bittner, Dieter Weichenhan, Charles D. Imbusch, Agnes Hotz-Wagenblatt, Thomas Hielscher, Achim Breiling, Giuseppina Federico, Hermann-Josef Gröne, Roland M. Schmid, Michael Rehli, Jakub Abramson, Markus Feuerer
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-09276-w

Epigenetic mechanisms regulating T-cell responses

Author(s): Christian Schmidl, Michael Delacher, Jochen Huehn, Markus Feuerer
Published in: Journal of Allergy and Clinical Immunology, Issue 142/3, 2018, Page(s) 728-743, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2018.07.014

Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF

Author(s): Michael Delacher, Charles D. Imbusch, Agnes Hotz-Wagenblatt, Jan-Philipp Mallm, Katharina Bauer, Malte Simon, Dania Riegel, André F. Rendeiro, Sebastian Bittner, Lieke Sanderink, Asmita Pant, Lisa Schmidleithner, Kathrin L. Braband, Bernd Echtenachter, Alexander Fischer, Valentina Giunchiglia, Petra Hoffmann, Matthias Edinger, Christoph Bock, Michael Rehli, Benedikt Brors, Christian Schmidl, Mark
Published in: Immunity, 2020, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2019.12.002

Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

Author(s): Michael Delacher, Malte Simon, Lieke Sanderink, Agnes Hotz-Wagenblatt, Marina Wuttke, Kathrin Schambeck, Lisa Schmidleithner, Sebastian Bittner, Asmita Pant, Uwe Ritter, Thomas Hehlgans, Dania Riegel, Verena Schneider, Florian Kai Groeber-Becker, Andreas Eigenberger, Claudia Gebhard, Nicholas Strieder, Alexander Fischer, Michael Rehli, Petra Hoffmann, Matthias Edinger, Till Strowig, Jochen Huehn,
Published in: Immunity, Issue 54/4, 2021, Page(s) 702-720.e17, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2021.03.007

Recirculating IL-1R2+ Tregs fine-tune intrathymic Treg development under inflammatory conditions

Author(s): Eirini Nikolouli, Yassin Elfaki, Susanne Herppich, Carsten Schelmbauer, Michael Delacher, Christine Falk, Ilgiz A. Mufazalov, Ari Waisman, Markus Feuerer, Jochen Huehn
Published in: Cellular & Molecular Immunology, Issue 18/1, 2021, Page(s) 182-193, ISSN 1672-7681
Publisher: Nature Publishing Group
DOI: 10.1038/s41423-019-0352-8