Project description DEENESFRITPL Green chemical synthesis using light-driven catalytic reduction reactions Developing alternative synthetic methods for creating valuable chemicals is crucial for a sustainable future. The ERC-funded GREENLIGHT_REDCAT project will use visible light and water to synthesise valuable chemicals. By combining photoredox catalysts and transition metal complex catalysts, GREENLIGHT_REDCAT aims to create green selective catalytic reduction processes for organic substrates. Project activities will be geared towards developing light-driven regioselective and enantioselective catalytic reduction reactions using cobalt coordination complexes, understanding the dynamics of cobalt-catalysed reductions and enhancing the performance of these reactions by self-assembling catalyst-photosensitiser materials. As a proof of concept, cobalt catalysts based on aminopyridine ligands have already shown promise in reducing ketones and aldehydes to alcohols using water. Show the project objective Hide the project objective Objective The development of alternative greener synthetic methods to transform renewable feedstocks into elaborated chemical structures mediated by solar light is a prerequisite for a future sustainable society. In this regard, this project entails the use of visible light as driving force and water as a source of hydrides for the synthesis of high-value chemicals.The project merges photoredox catalysis with 1st row transition coordination complexes catalysis to open a new avenue for greener selective catalytic reduction processes for organic substrates. The ground-breaking nature of the project is: A) Develop light-driven region- and/or enantioselective catalytic reductions using well-defined cobalt coordination complexes with aminopyridine ligands, initially developed for water reduction. Sterics, electronics and supramolecular interactions (apolar cavities and chiral pockets) will be studied to proper control of the selectivity in the reduction of i) C=E and C=C bonds and ii) in the C-C inter- and intramolecular reductive homo- or heterocouplings. B) Fundamental understanding of the light-driven cobalt catalysed reductions characterizing intermediates that are involved in the reactivity, kinetics and labelling studies as well as performing computational modelling of reaction mechanisms. The basic understanding of operative mechanisms will expedite a new methodology for electrophile-electrophile umpolung couplings. C) Enhance catalytic performance of the light-driven cobalt catalysed reductions by self-assembling of catalyst-photosensitizer into carbon based pi-conjugated materials through noncovalent supramolecular interactions. Likewise, it will allow electrode immobilization for electrocatalysed reductions using water as a source of protons and electrons. As a proof of concept, cobalt catalysts based on aminopyridine ligands have been shown highly active in the light-driven reduction of ketones and aldehydes to alcohols, using water as the source of hydrogen atom. Fields of science natural scienceschemical sciencesorganic chemistryaldehydesnatural scienceschemical sciencesorganic chemistryketonesnatural scienceschemical sciencescatalysiselectrocatalysisnatural scienceschemical sciencesinorganic chemistrytransition metalsnatural scienceschemical sciencesorganic chemistryalcohols Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Topic(s) ERC-CoG-2014 - ERC Consolidator Grant Call for proposal ERC-2014-CoG See other projects for this call Funding Scheme ERC-COG - Consolidator Grant Coordinator FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA Net EU contribution € 1 999 063,00 Address Avenida paissos catalans 16 43007 Tarragona Spain See on map Region Este Cataluña Tarragona Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Beneficiaries (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA Spain Net EU contribution € 1 999 063,00 Address Avenida paissos catalans 16 43007 Tarragona See on map Region Este Cataluña Tarragona Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
