Skip to main content

Identifying microbiotal triggers of inflammatory bowel disease through the lens of the immune system

Searching for OpenAIRE data...

Publications

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

Author(s): Konrad Aden, Florian Tran, Go Ito, Raheleh Sheibani-Tezerji, Simone Lipinski, Jan W. Kuiper, Markus Tschurtschenthaler, Svetlana Saveljeva, Joya Bhattacharyya, Robert Häsler, Kareen Bartsch, Anne Luzius, Marlene Jentzsch, Maren Falk-Paulsen, Stephanie T. Stengel, Lina Welz, Robin Schwarzer, Björn Rabe, Winfried Barchet, Stefan Krautwald, Gunther Hartmann, Manolis Pasparakis, Richard S. Blumberg,
Published in: The Journal of Experimental Medicine, 2018, Page(s) jem.20171029, ISSN 0022-1007
DOI: 10.1084/jem.20171029

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation

Author(s): Konrad Aden, Ateequr Rehman, Maren Falk-Paulsen, Thomas Secher, Jan Kuiper, Florian Tran, Steffen Pfeuffer, Raheleh Sheibani-Tezerji, Alexandra Breuer, Anne Luzius, Marlene Jentzsch, Robert Häsler, Susanne Billmann-Born, Olga Will, Simone Lipinski, Richa Bharti, Timon Adolph, Juan L. Iovanna, Sarah L. Kempster, Richard S. Blumberg, Stefan Schreiber, Burkhard Becher, Mathias Chamaillard, Arthur
Published in: Cell Reports, Issue 16/8, 2016, Page(s) 2208-2218, ISSN 2211-1247
DOI: 10.1016/j.celrep.2016.07.054

Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation

Author(s): Shuhei Hosomi, Joep Grootjans, Markus Tschurtschenthaler, Niklas Krupka, Juan D. Matute, Magdalena B. Flak, Eduardo Martinez-Naves, Manuel Gomez del Moral, Jonathan N. Glickman, Mizuki Ohira, Lewis L. Lanier, Arthur Kaser, Richard Blumberg
Published in: The Journal of Experimental Medicine, Issue 214/10, 2017, Page(s) 2985-2997, ISSN 0022-1007
DOI: 10.1084/jem.20162041

Personalized Treatment in Inflammatory Bowel Disease: For Another Time

Author(s): Nicole C. Kaneider, Arthur Kaser
Published in: Gastroenterology, 2018, ISSN 0016-5085
DOI: 10.1053/j.gastro.2018.09.004

New Insights Into the Regulation of Natural-Killer Group 2 Member D (NKG2D) and NKG2D-Ligands: Endoplasmic Reticulum Stress and CEA-Related Cell Adhesion Molecule 1

Author(s): Shuhei Hosomi, Joep Grootjans, Yu-Hwa Huang, Arthur Kaser, Richard S. Blumberg
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.01324

The unfolded protein response in immunity and inflammation

Author(s): Joep Grootjans, Arthur Kaser, Randal J. Kaufman, Richard S. Blumberg
Published in: Nature Reviews Immunology, Issue 16/8, 2016, Page(s) 469-484, ISSN 1474-1733
DOI: 10.1038/nri.2016.62

GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump

Author(s): Georg Schneditz, Joshua E. Elias, Ester Pagano, M. Zaeem Cader, Svetlana Saveljeva, Kathleen Long, Subhankar Mukhopadhyay, Maryam Arasteh, Trevor D. Lawley, Gordon Dougan, Andrew Bassett, Tom H. Karlsen, Arthur Kaser, Nicole C. Kaneider
Published in: Science Signaling, Issue 12/562, 2019, Page(s) eaau9048, ISSN 1937-9145
DOI: 10.1126/scisignal.aau9048

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

Author(s): Joep Grootjans, Niklas Krupka, Shuhei Hosomi, Juan D. Matute, Thomas Hanley, Svetlana Saveljeva, Thomas Gensollen, Jarom Heijmans, Hai Li, Julien P. Limenitakis, Stephanie C. Ganal-Vonarburg, Shengbao Suo, Adrienne M. Luoma, Yosuke Shimodaira, Jinzhi Duan, David Q. Shih, Margaret E. Conner, Jonathan N. Glickman, Gwenny M. Fuhler, Noah W. Palm, Marcel R. de Zoete, C. Janneke van der Woude, Guo-Chen
Published in: Science, Issue 363/6430, 2019, Page(s) 993-998, ISSN 0036-8075
DOI: 10.1126/science.aat7186

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis

Author(s): Markus Tschurtschenthaler, Timon E. Adolph, Jonathan W. Ashcroft, Lukas Niederreiter, Richa Bharti, Svetlana Saveljeva, Joya Bhattacharyya, Magdalena B. Flak, David Q. Shih, Gwenny M. Fuhler, Miles Parkes, Kenji Kohno, Takao Iwawaki, C. Janneke van der Woude, Heather P. Harding, Andrew M. Smith, Maikel P. Peppelenbosch, Stephan R. Targan, David Ron, Philip Rosenstiel, Richard S. Blumberg, Arthur K
Published in: The Journal of Experimental Medicine, Issue 214/2, 2017, Page(s) 401-422, ISSN 0022-1007
DOI: 10.1084/jem.20160791

The road to Crohn's disease

Author(s): Arthur Kaser, Richard S. Blumberg
Published in: Science, Issue 357/6355, 2017, Page(s) 976-977, ISSN 0036-8075
DOI: 10.1126/science.aao4158