FIBER-optic sensors for Smart Thermal Ablation at Radiofrequency

Project Information

FIBERSTAR

Grant agreement ID: 652871

DOI 10.3030/652871

Project terminated on 7 July 2016

Start date 1 September 2016

End date 31 August 2018

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 158 121,60

EU contribution € 158 121,60

Coordinated by

UNIVERSIDAD CARLOS III DE MADRID
Spain

Objective

FIBERSTAR is a multidisciplinary project aimed at the development of point-of-care optical fiber sensors to support non-invasive radiofrequency thermal ablation (RFTA) of tumors.

RFTA is an interventional medical procedure that brings tumor cells to mortality by generating a spatially selective high-temperature field, localized within the tumor, using a percutaneous ablation device. RFTA provides ablation up to 5 cm size in hard tissues (kidney, lung), while ablation size is limited to 3 cm in liver; on the other hand, the miniature ablation device ensures a non-invasive outpatient treatment.

In clinical procedures, RFTA is an image-guided procedure, which limits its efficiency. The possibility to install miniature, biocompatible, and quasi-distributed fiber-optic sensors on RFTA device, returning real-time biophysical data, can disrupt RFTA procedure. The applicant has carried out significant groundwork in the application of optical fiber sensors to ex-vivo thermal ablation on porcine liver phantoms.

Building on groundwork, FIBERSTAR aims at the development of innovative fiber-optic sensors that aim at solving the main limitations of RFTA. Research addresses the development of (1) a sensor embedding pressure and distributed temperature on a single fiber, to be installed on the RFTA device, (2) a sensor for positioning RFTA device in tumor, (3) miniature quasi-distributed temperature sensors to detect the approaching of the ablation.

FIBERSTAR aims at building four-fold impact:
1) Implement and demonstrate smart-RFTA, whereas real-time sensors data are used to drive the RFTA treatment in close-loop complementing imaging data.
2) Extend RFTA to safe treatment of prostatic and pancreatic tumors, using sensors to protect key organs from ablation.
3) Provide disruptive improvement of treatment of encapsulated tumors, implementing pressure detection.
4) Provide a quantified improvement of RFTA outcome in terms of reduction of failure rate and predictability.

Fields of science

• engineering and technology › electrical engineering, electronic engineering, information engineering › information engineering › telecommunications › radio technology › radio frequency
• engineering and technology › materials engineering › fibers
• social sciences › sociology › demography › mortality
• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › sensors
• natural sciences › physical sciences › optics › fibre optics

Keywords

• Optical fiber sensors
• interventional cancer care
• thermal ablation
• radiofrequency thermal ablation (RFTA)

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF)

Call for proposal

H2020-MSCA-IF-2014

Funding Scheme

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Coordinator

UNIVERSIDAD CARLOS III DE MADRID

• Net EU contribution: € 158 121,60
• Address: Calle madrid 126 ; 28903 Getafe (madrid) ; Spain
• Region: Comunidad de Madrid › Comunidad de Madrid › Madrid
• Activity type: Higher or Secondary Education Establishments
• Other funding: € 0,00