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Motor simulation: Evaluating the role of mirror neurons in humans through ECOG and Lesion Studies

Objective

One of the most intriguing, yet controversial findings in neuroscience in the past two decades is the discovery of the mirror neuron system (MNS). These visuo-motor neurons discharge both when a monkey does a particular goal-directed action and also when it observes another individual doing a similar action. The result of this mechanism is thought to be the capacity to recognize that an individual is performing an action, to differentiate this action from others analogous to it, and to use this information in order to act appropriately. This mechanism has been proposed as the basis for social cognition, and deficits in social understanding, such as those seen in autism spectrum disorder, have been linked to deficits in the MNS. Here I propose to use 2 novel approaches to address the neurobiological and behavioral significance of the human mirror neuron system (hMNS). (a) I will use Electrocorticography (ECoG) in neurosurgical patients to assess where, when, and how neurons in the prefrontal, parietal and sensorimotor regions are involved in action recognition. (b) I will employ scalp EEG and behavioral measures in a unique cohort of patients with damage centered in the Inferior Frontal Gyrus (IFG) or the Inferior Parietal Lobule (IPL). If the IFG and IPL are the core regions of the hMNS, patients with lesions to these regions should show deficits in understanding others’ actions, intentions and emotions (when these are expressed by body motion). This research will further our knowledge on the neural underpinnings of social understanding, and on the consequences of deficits in these neural networks.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2014

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Coordinator

THE HEBREW UNIVERSITY OF JERUSALEM
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 263 385,00
Address
EDMOND J SAFRA CAMPUS GIVAT RAM
91904 JERUSALEM
Israel

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Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 263 385,00

Partners (1)

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