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INNOVATIVE AUTONOMOUS ELECTRICAL BIOSENSOR SYNERGISTICALLY ASSEMBLED INSIDE A PASSIVE DIRECT METHANOL FUEL CELL FOR SCREENING CANCER BIOMARKERS

Objective

Biosensors possess recognition elements that bind to target molecules which lead to detectable signals; they are made of two basic components: (i) a bioreceptor or biorecognition element; and (ii) a transducer element. The bioreceptor system interacts with the target analyte and this interaction is monitored by the transducer, which converts the information into a measurable effect such as an electrical, optical or mass-sensitive signal.
This project proposes the development of an autonomous electrochemical biosensor that is lightweight, disposable and low cost by using an outstanding innovative approach: hosting synergistically the bioreceptor element inside a passive direct methanol fuel cell (DMFC). Such approach will provide an electrically independent, very simple, miniaturized, autonomous electrical biosensor. The electrical dependency is eliminated by coupling the biosensor to an electrochemical transducer that is capable of autonomous energy production, the fuel cell. This work proposes a merge between electrical biosensors and fuel cells, combining the advantages of both areas of research in a single synergetic device.
In this envisaged innovative device, the electrical signal obtained from the DMFC is directly related to the concentration of the cancer biomarker in the sample analyzed. The proposed electrochemical biosensor will be completely autonomous operating at room temperature and using the oxygen present in the air, thereby allowing diagnosis everywhere.

Field of science

  • /medical and health sciences/clinical medicine/oncology/cancer
  • /engineering and technology/environmental engineering/energy and fuels/fuel cell
  • /engineering and technology/environmental biotechnology/biosensing

Call for proposal

H2020-FETOPEN-2014-2015-RIA
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO
Address
Rua Dr Antonio Bernardino De Almeida 431
4200-072 Porto
Portugal
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 836 928,75

Participants (4)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 699 311,25
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
UNINOVA-INSTITUTO DE DESENVOLVIMENTO DE NOVAS TECNOLOGIAS-ASSOCIACAO
Portugal
EU contribution
€ 574 475
Address
Campus Da Caparica Quinta Da Torre
2829-516 Caparica
Activity type
Research Organisations
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
Finland
EU contribution
€ 708 313,75
Address
Tekniikantie 21
02150 Espoo
Activity type
Research Organisations
AARHUS UNIVERSITET
Denmark
EU contribution
€ 527 631,25
Address
Nordre Ringgade 1
8000 Aarhus C
Activity type
Higher or Secondary Education Establishments