A gene expression test in blood for breast cancer

Informations projet

BLOBREC

N° de convention de subvention: 665633

DOI

10.3030/665633

Projet clôturé

Date de signature de la CE 20 Avril 2015

Date de début 1 Mai 2015

Date de fin 30 Avril 2016

Financé au titre de

• EXCELLENT SCIENCE - European Research Council (ERC)

Coût total

€ 143 933,00

Contribution de l’UE

€ 143 933,00

Coordonné par

UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET
Norway

Periodic Reporting for period 1 - BLOBREC (A gene expression test in blood for breast cancer)

Période du rapport: 2015-05-01 au 2016-04-30

Résumé du contexte et des objectifs généraux du projet

The work done under this PoC has confirmed the properties of the BLOBREC test as a gene expression test for breast cancer using peripheral blood. The original set of 50 genes remain valid. Additional analyses showed no inferences with stress before the second look, hormone use or tobacco smoking. Improvement in blood sampling and logistics improved the specificity. The use of pooled samples or a standard further improved the test properties.
We propose further investigations on:
A. The independence of the BLOBREC test in relation to mammogram
B. The use of BLOBREC in the primary screening or at follow-up or second look at the breast cancer screening program.
C. A more suitable, cheap and fast technology for the commercialization of the test