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Ebola Virus Disease - correlates of protection, determinants of outcome, and clinical management

Deliverables

Publications

Development of an antibody capture ELISA using inactivated Ebola Zaire Makona virus

Author(s): Verena Krähling, Dirk Becker, Cornelius Rohde, Markus Eickmann, Yonca Eroğlu, Astrid Herwig, Romy Kerber, Katharina Kowalski, Júlia Vergara-Alert, Stephan Becker
Published in: Medical Microbiology and Immunology, 205/2, 2016, Page(s) 173-183, ISSN 0300-8584
Publisher: Springer Verlag
DOI: 10.1007/s00430-015-0438-6

Dilemmas in Managing Pregnant Women With Ebola: 2 Case Reports: Table 1.

Author(s): Séverine Caluwaerts, Tessy Fautsch, Daphne Lagrou, Michel Moreau, Alseny Modet Camara, Stephan Günther, Antonino Di Caro, Benny Borremans, Fara Raymond Koundouno, Joseph Akoi Bore, Christopher H. Logue, Martin Richter, Roman Wölfel, Eeva Kuisma, Andreas Kurth, Stephen Thomas, Gillian Burkhardt, Elin Erland, Fanshen Lionetto, Patricia Lledo Weber, Olimpia de la Rosa, Hassan Macpherson, Michel Va
Published in: Clinical Infectious Diseases, 62/7, 2016, Page(s) 903-905, ISSN 1058-4838
Publisher: University of Chicago Press
DOI: 10.1093/cid/civ1024

Functional characterization of adaptive mutations during the West African Ebola virus outbreak

Author(s): Erik Dietzel, Gordian Schudt, Verena Krähling, Mikhail Matrosovich, Stephan Becker
Published in: Journal of Virology, 2016, Page(s) JVI.01913-16, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/JVI.01913-16

Ebola Virus Disease Is Characterized by Poor Activation and Reduced Levels of Circulating CD16 + Monocytes

Author(s): Anja Lüdtke, Paula Ruibal, Beate Becker-Ziaja, Monika Rottstegge, David M. Wozniak, Mar Cabeza-Cabrerizo, Anja Thorenz, Romy Weller, Romy Kerber, Juliana Idoyaga, N'Faly Magassouba, Martin Gabriel, Stephan Günther, Lisa Oestereich, César Muñoz-Fontela
Published in: Journal of Infectious Diseases, 214/suppl 3, 2016, Page(s) S275-S280, ISSN 0022-1899
Publisher: University of Chicago Press
DOI: 10.1093/infdis/jiw260

Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015

Author(s): Romy Kerber, Ralf Krumkamp, Boubacar Diallo, Anna Jaeger, Martin Rudolf, Simone Lanini, Joseph Akoi Bore, Fara Raymond Koundouno, Beate Becker-Ziaja, Erna Fleischmann, Kilian Stoecker, Silvia Meschi, Stéphane Mély, Edmund N. C. Newman, Fabrizio Carletti, Jasmine Portmann, Misa Korva, Svenja Wolff, Peter Molkenthin, Zoltan Kis, Anne Kelterbaum, Anne Bocquin, Thomas Strecker, Alexandra Fizet, Conc
Published in: Journal of Infectious Diseases, 214/suppl 3, 2016, Page(s) S250-S257, ISSN 0022-1899
Publisher: University of Chicago Press
DOI: 10.1093/infdis/jiw269

Evaluation of RealStar Reverse Transcription–Polymerase Chain Reaction Kits for Filovirus Detection in the Laboratory and Field

Author(s): Toni Rieger, Romy Kerber, Hussein El Halas, Elisa Pallasch, Sophie Duraffour, Stephan Günther, Stephan Ölschläger
Published in: Journal of Infectious Diseases, 214/suppl 3, 2016, Page(s) S243-S249, ISSN 0022-1899
Publisher: University of Chicago Press
DOI: 10.1093/infdis/jiw246

Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days

Author(s): Boubacar Diallo, Daouda Sissoko, Nicholas J. Loman, Hadja Aïssatou Bah, Hawa Bah, Mary Claire Worrell, lya Saidou Conde, Ramata Sacko, Samuel Mesfin, Angelo Loua, Jacques Katomba Kalonda, Ngozi A. Erondu, Benjamin A. Dahl, Susann Handrick, Ian Goodfellow, Luke W. Meredith, Matthew Cotten, Umaru Jah, Raoul Emeric Guetiya Wadoum, Pierre Rollin, N'Faly Magassouba, Denis Malvy, Xavier Anglaret, Miles
Published in: Clinical Infectious Diseases, 63/10, 2016, Page(s) 1353-1356, ISSN 1058-4838
Publisher: University of Chicago Press
DOI: 10.1093/cid/ciw601

Real-time, portable genome sequencing for Ebola surveillance

Author(s): Joshua Quick, Nicholas J. Loman, Sophie Duraffour, Jared T. Simpson, Ettore Severi, Lauren Cowley, Joseph Akoi Bore, Raymond Koundouno, Gytis Dudas, Amy Mikhail, Nobila Ouédraogo, Babak Afrough, Amadou Bah, Jonathan H. J. Baum, Beate Becker-Ziaja, Jan Peter Boettcher, Mar Cabeza-Cabrerizo, Álvaro Camino-Sánchez, Lisa L. Carter, Juliane Doerrbecker, Theresa Enkirch, Isabel García- Dorival, Nico
Published in: Nature, 530/7589, 2016, Page(s) 228-232, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature16996

Field Evaluation of Capillary Blood Samples as a Collection Specimen for the Rapid Diagnosis of Ebola Virus Infection During an Outbreak Emergency

Author(s): Thomas Strecker, Bernadett Palyi, Heinz Ellerbrok, Sylvie Jonckheere, Hilde de Clerck, Joseph Akoi Bore, Martin Gabriel, Kilian Stoecker, Markus Eickmann, Michel van Herp, Pierre Formenty, Antonino Di Caro, Stephan Becker
Published in: Clinical Infectious Diseases, 61/5, 2015, Page(s) 669-675, ISSN 1058-4838
Publisher: University of Chicago Press
DOI: 10.1093/cid/civ397

Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa

Author(s): Miles W. Carroll, David A. Matthews, Julian A. Hiscox, Michael J. Elmore, Georgios Pollakis, Andrew Rambaut, Roger Hewson, Isabel García-Dorival, Joseph Akoi Bore, Raymond Koundouno, Saïd Abdellati, Babak Afrough, John Aiyepada, Patience Akhilomen, Danny Asogun, Barry Atkinson, Marlis Badusche, Amadou Bah, Simon Bate, Jan Baumann, Dirk Becker, Beate Becker-Ziaja, Anne Bocquin, Benny Borremans, A
Published in: Nature, 524/7563, 2015, Page(s) 97-101, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature14594

Ebola virus dynamics in mice treated with favipiravir

Author(s): Vincent Madelain, Lisa Oestereich, Frederik Graw, Thi Huyen Tram Nguyen, Xavier de Lamballerie, France Mentré, Stephan Günther, Jeremie Guedj
Published in: Antiviral Research, 123, 2015, Page(s) 70-77, ISSN 0166-3542
Publisher: Elsevier BV
DOI: 10.1016/j.antiviral.2015.08.015

Unique human immune signature of Ebola virus disease in Guinea

Author(s): Paula Ruibal, Lisa Oestereich, Anja Lüdtke, Beate Becker-Ziaja, David M. Wozniak, Romy Kerber, Miša Korva, Mar Cabeza-Cabrerizo, Joseph A. Bore, Fara Raymond Koundouno, Sophie Duraffour, Romy Weller, Anja Thorenz, Eleonora Cimini, Domenico Viola, Chiara Agrati, Johanna Repits, Babak Afrough, Lauren A. Cowley, Didier Ngabo, Julia Hinzmann, Marc Mertens, Inês Vitoriano, Christopher H. Logue, Jan
Published in: Nature, 533/7601, 2016, Page(s) 100-104, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature17949

Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection

Author(s): C Agrati, C Castilletti, R Casetti, A Sacchi, L Falasca, F Turchi, N Tumino, V Bordoni, E Cimini, D Viola, E Lalle, L Bordi, S Lanini, F Martini, E Nicastri, N Petrosillo, V Puro, M Piacentini, A Di Caro, G P Kobinger, A Zumla, G Ippolito, M R Capobianchi
Published in: Cell Death and Disease, 7/3, 2016, Page(s) e2164, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/cddis.2016.55

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

Author(s): Daouda Sissoko, Cedric Laouenan, Elin Folkesson, Abdoul-Bing M’Lebing, Abdoul-Habib Beavogui, Sylvain Baize, Alseny-Modet Camara, Piet Maes, Susan Shepherd, Christine Danel, Sara Carazo, Mamoudou N. Conde, Jean-Luc Gala, Géraldine Colin, Hélène Savini, Joseph Akoi Bore, Frederic Le Marcis, Fara Raymond Koundouno, Frédéric Petitjean, Marie-Claire Lamah, Sandra Diederich, Alexis Tounkara, Gee
Published in: PLOS Medicine, 13/3, 2016, Page(s) e1001967, ISSN 1549-1676
Publisher: PLOS
DOI: 10.1371/journal.pmed.1001967