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Chimeric Antigen Receptors (CARs) for Advanced Therapies

Deliverables

"Report on implementation of ""CAR sharing"""

"Report on implementation of ""CAR sharing"""

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Publications

Automated Manufacturing of Potent CD20-Directed Chimeric Antigen Receptor T Cells for Clinical Use

Author(s): Dominik Lock, Nadine Mockel-Tenbrinck, Katharina Drechsel, Carola Barth, Daniela Mauer, Thomas Schaser, Carolin Kolbe, Wael Al Rawashdeh, Janina Brauner, Olaf Hardt, Natali Pflug, Udo Holtick, Peter Borchmann, Mario Assenmacher, Andrew Kaiser
Published in: Human Gene Therapy, Issue 28/10, 2017, Page(s) 914-925, ISSN 1043-0342
DOI: 10.1089/hum.2017.111

<em>Ex Vivo</em> Imaging of Resident CD8 T Lymphocytes in Human Lung Tumor Slices Using Confocal Microscopy

Author(s): Elisa Peranzoni, Houcine Bougherara, Sarah Barrin, Audrey Mansuet-Lupo, Marco Alifano, Diane Damotte, Emmanuel Donnadieu
Published in: Journal of Visualized Experiments, Issue 130, 2017, ISSN 1940-087X
DOI: 10.3791/55709

Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors

Author(s): Johanna Reul, Janina Frisch, Christine E. Engeland, Frederic B. Thalheimer, Jessica Hartmann, Guy Ungerechts, Christian J. Buchholz
Published in: Frontiers in Oncology, Issue 9, 2019, ISSN 2234-943X
DOI: 10.3389/fonc.2019.00052

Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System Manufacturing

Author(s): Constanze Radek, Ornellie Bernadin, Katharina Drechsel, Nicole Cordes, Rita Pfeifer, Pia Sträßer, Mirella Mormin, Alejandra Gutierrez-Guerrero, François-loïc Cosset, Andrew D. Kaiser, Thomas Schaser, Anne Galy, Els Verhoeyen, Ian C.D. Johnston
Published in: Human Gene Therapy, Issue 30/12, 2019, Page(s) 1477-1493, ISSN 1043-0342
DOI: 10.1089/hum.2019.157