Chimeric Antigen Receptors (CARs) for Advanced Therapies

Livrables

Report on ethical issues relevant to CAR T-cell therapies

Report on proceedings of a workshop on regulatory issues
Optimized integrated CAR T-cell process validated by manufacturing centres
Report on results of survey
"Report on implementation of ""CAR sharing"""
Open access summary report

Project website

Publications

Automated Manufacturing of Potent CD20-Directed Chimeric Antigen Receptor T Cells for Clinical Use

Auteurs: Dominik Lock, Nadine Mockel-Tenbrinck, Katharina Drechsel, Carola Barth, Daniela Mauer, Thomas Schaser, Carolin Kolbe, Wael Al Rawashdeh, Janina Brauner, Olaf Hardt, Natali Pflug, Udo Holtick, Peter Borchmann, Mario Assenmacher, Andrew Kaiser
Publié dans: Human Gene Therapy, Numéro 28/10, 2017, Page(s) 914-925, ISSN 1043-0342
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/hum.2017.111

<em>Ex Vivo</em> Imaging of Resident CD8 T Lymphocytes in Human Lung Tumor Slices Using Confocal Microscopy

Auteurs: Elisa Peranzoni, Houcine Bougherara, Sarah Barrin, Audrey Mansuet-Lupo, Marco Alifano, Diane Damotte, Emmanuel Donnadieu
Publié dans: Journal of Visualized Experiments, Numéro 130, 2017, ISSN 1940-087X
Éditeur: MYJoVE Corporation
DOI: 10.3791/55709

Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors

Auteurs: Johanna Reul, Janina Frisch, Christine E. Engeland, Frederic B. Thalheimer, Jessica Hartmann, Guy Ungerechts, Christian J. Buchholz
Publié dans: Frontiers in Oncology, Numéro 9, 2019, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2019.00052

Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System Manufacturing

Auteurs: Constanze Radek, Ornellie Bernadin, Katharina Drechsel, Nicole Cordes, Rita Pfeifer, Pia Sträßer, Mirella Mormin, Alejandra Gutierrez-Guerrero, François-loïc Cosset, Andrew D. Kaiser, Thomas Schaser, Anne Galy, Els Verhoeyen, Ian C.D. Johnston
Publié dans: Human Gene Therapy, Numéro 30/12, 2019, Page(s) 1477-1493, ISSN 1043-0342
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/hum.2019.157

Clinical development of CAR T cells—challenges and opportunities in translating innovative treatment concepts

Auteurs: Jessica Hartmann, Martina Schüßler‐Lenz, Attilio Bondanza, Christian J Buchholz
Publié dans: EMBO Molecular Medicine, 2017, Page(s) e201607485, ISSN 1757-4676
Éditeur: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201607485

Droits de propriété intellectuelle

CHIMERIC ANTIGEN RECEPTORS THAT BIND TO PROSTATE SPECIFIC MEMBRANE ANTIGEN

Numéro de demande/publication: 18 180026
Date: 2018-06-27
Demandeur(s): UNIVERSITAETSKLINIKUM FREIBURG

Livrables

Publications

Droits de propriété intellectuelle

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