INtestinal Tissue ENgineering Solution

We will set up a standard Operating Procedure for obtaining the tissue sample that is required for the in vitro procedure up to the transplantation. The protocol will describe the regulatory approval, the logistics and the technical description of the isolation up to taking it into culture.

A new tool for engaging publics, including school students and patients, around short bowel syndrome, and potential clinical uses of intestinal stem cells.

Creation and launch of INTENS project-specific website at www.intens.info as well as linking from EuroStemCell, PINNT, Short Gut Foundation and other relevant websites.

Author(s): Meritxell Huch, Juergen A. Knoblich, Matthias P. Lutolf, Alfonso Martinez-Arias
Published in: Development, Issue 144/6, 2017, Page(s) 938-941, ISSN 0950-1991
DOI: 10.1242/dev.150201

Author(s): Yoji Tabata, Matthias P. Lutolf
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
DOI: 10.1038/srep44711

Author(s): Giuliana Rossi, Andrea Manfrin, Matthias P. Lutolf
Published in: Nature Reviews Genetics, Issue 19/11, 2018, Page(s) 671-687, ISSN 1471-0056
DOI: 10.1038/s41576-018-0051-9

Author(s): Shiro Yui, Luca Azzolin, Martti Maimets, Marianne Terndrup Pedersen, Robert P. Fordham, Stine L. Hansen, Hjalte L. Larsen, Jordi Guiu, Mariana R.P. Alves, Carsten F. Rundsten, Jens V. Johansen, Yuan Li, Chris D. Madsen, Tetsuya Nakamura, Mamoru Watanabe, Ole H. Nielsen, Pawel J. Schweiger, Stefano Piccolo, Kim B. Jensen
Published in: Cell Stem Cell, Issue 22/1, 2018, Page(s) 35-49.e7, ISSN 1934-5909
DOI: 10.1016/j.stem.2017.11.001

Author(s): Alfonso Martinez Arias, Matthias P. Lutolf
Published in: Current Opinion in Systems Biology, Issue 11, 2018, Page(s) 50-56, ISSN 2452-3100
DOI: 10.1016/j.coisb.2018.07.007

Author(s): Conor J. McCann, Julie E. Cooper, Dipa Natarajan, Benjamin Jevans, Laura E. Burnett, Alan J. Burns, Nikhil Thapar
Published in: Nature Communications, Issue 8, 2017, Page(s) 15937, ISSN 2041-1723
DOI: 10.1038/ncomms15937

Author(s): Claudia Y. Janda, Luke T. Dang, Changjiang You, Junlei Chang, Wim de Lau, Zhendong A. Zhong, Kelley S. Yan, Owen Marecic, Dirk Siepe, Xingnan Li, James D. Moody, Bart O. Williams, Hans Clevers, Jacob Piehler, David Baker, Calvin J. Kuo, K. Christopher Garcia
Published in: Nature, Issue 545/7653, 2017, Page(s) 234-237, ISSN 0028-0836
DOI: 10.1038/nature22306

Author(s): Andrew Trecartin, Soula Danopoulos, Ryan Spurrier, Hanaa Knaneh-Monem, Michael Hiatt, Barbara Driscoll, Christian Hochstim, Denise Al-Alam, Tracy C. Grikscheit
Published in: Tissue Engineering Part C: Methods, Issue 22/11, 2016, Page(s) 1049-1057, ISSN 1937-3384
DOI: 10.1089/ten.TEC.2016.0261

Author(s): Nirmala Mavila, Andrew Trecartin, Ryan Spurrier, Yi Xiao, Xiaogang Hou, David James, Xiaowei Fu, Brian Truong, Clara Wang, Gerald S. Lipshutz, Kasper S. Wang, Tracy C. Grikscheit
Published in: STEM CELLS Translational Medicine, Issue 6/1, 2017, Page(s) 238-248, ISSN 2157-6564
DOI: 10.5966/sctm.2016-0205