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Children’s Liver Tumour European Research Network

Deliverables

Registration in ISRCTN

Indicates successful registration of the trial on a publically accessible database.

Website activation

Website activation

Project Management

Project Management

Protocol finalisation and submission to EC.

Indicates successful development of key trial documents. Submission to EC in accordance with EC H2020 clinical trial requirements.

Project Data Management Plan

Project Data Management Plan

Dissemination and Communication Plan: and updated regularly

To document clearly how information about CHILTERN will be disseminated to all partners and participants during the project. This will also involve WP leads who will be responsible for providing information about their WP.

Protocols for standardised collection of clinical samples and sample analysis

Protocols for standardised collection of clinical samples and sample analysis

Publication Policy

To document clearly how the results from all the work packages will made available to the appropriate audiences; including clinicians, researchers, patients and the public

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Publications

Hepatoblastoma and Paediatric Hepatocellular Carcinoma: An Update

Author(s): Sarangarajan Ranganathan, Dolores Lopez-Terrada, Rita Alaggio
Published in: Pediatr Dev Pathol, Mar-Apr 2020;23(2), 2020, Page(s) 79-95, ISSN 1093-5266
Publisher: Springer Verlag
DOI: 10.1177/1093526619875228

Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications

Author(s): Carrillo-Reixach et al, J Hepatol,
Published in: Hepatol, 2020, 2020, ISSN 0168-8278
Publisher: Elsevier BV
DOI: 10.1016/j.jhep.2020.03.025

A combined clinical and biological risk score predicts outcome in hepatoblastoma patients.

Author(s): Cairo S., Armengol C., Maibach R., Häberle B., Becker K., Carrillo-Reixach J., Guettier C., Vokuhl C., Schmid I., Buendia M.-A., Branchereau S., von Schweinitz D., Kappler R
Published in: Eur. J. Cancer, 141, 2020, Page(s) 30-39, ISSN 0959-8049
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.ejca.2020.09.026

Focal Adhesion Kinase (FAK) Over-expression and Prognostic Implication in Paediatric Hepatocellular Carcinoma

Author(s): Paola Francalanci, Isabella Giovannoni, Cristiano De Stefanis, Ilaria Romito, Chiara Grimaldi, Aurora Castellano, Rita Alaggio, Anna Alisi
Published in: J Mol Sci, Aug 12;21(16):E5795, 2020, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21165795

SP8 Promotes an Aggressive Phenotype in Hepatoblastoma via FGF8 Activation

Author(s): Wagner AE, Schwarzmayr T, Haberle B, Vokuhl C, Schmid I, Kaller M, Hermeking H, von Schweinitz D, Kappler R
Published in: Cancers, 12 (8), 2020, Page(s) 2294, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082294