Enhancing Research in Ageing at the University of Coimbra

Livrables

Publication of ERA Chair team position announcement
Publication of ERA Chair website (phase 2)
ERA Chair laboratory fully operational (phase 1)
Publication of ERA Chair position announcement
Scientific lecture at UC based on main achievements accomplished up to the third year of ERA@UC
Production of ERA Chair leaflet
Public lecture for science awareness on ageing research based on the outcomes of ERA@UC project
Organization of awareness events and press releases about the ERA Chair team research
Identification of key requirements for ERA Chair position announcement
Laboratory fully operational (phase 2)
Publication of ERA Chair website (Phase 1)

Publication of ERA Chair website Phase 1

A one-page statement with the collection of peer-reviewed publications (in the research field of ageing) of the coordinator in high impact journals
ERA Chair Recruitment and Monitoring Team
Selection of ERA Chair collaborators
Report on the selection process of the ERA Chair holder
ERA Chair MIA International Advisory Board
Selection of best candidate for ERA Chair holder
Institutional appointment of ERA Chair holder (provisional, depending on evaluation outcome)
ERA Chair support team in place

Publications

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition

Auteurs: Sezin Aday, Janet Zoldan, Marie Besnier, Laura Carreto, Jaimy Saif, Rui Fernandes, Tiago Santos, Liliana Bernardino, Robert Langer, Costanza Emanueli, Lino Ferreira
Publié dans: Nature Communications, Numéro 8/1, 2017, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-017-00746-7

Stem cells as vehicles and targets of nanoparticles

Auteurs: Sonia Pinho, Maria H. Macedo, Catarina Rebelo, Bruno Sarmento, Lino Ferreira
Publié dans: Drug Discovery Today, Numéro 23/5, 2018, Page(s) 1071-1078, ISSN 1359-6446
Éditeur: Elsevier BV
DOI: 10.1016/j.drudis.2018.01.030

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes

Auteurs: P. José Gouveia, S. Rosa, L. Ricotti, B. Abecasis, H.V. Almeida, L. Monteiro, J. Nunes, F. Sofia Carvalho, M. Serra, S. Luchkin, A. Leonidovitch Kholkin, P. Marques Alves, P. Jorge Oliveira, R. Carvalho, A. Menciassi, R. Pires das Neves, L. Silva Ferreira
Publié dans: Biomaterials, Numéro 139, 2017, Page(s) 213-228, ISSN 0142-9612
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2017.05.048

Light-triggerable formulations for the intracellular controlled release of biomolecules

Auteurs: Miguel M. Lino, Lino Ferreira
Publié dans: Drug Discovery Today, Numéro 23/5, 2018, Page(s) 1062-1070, ISSN 1359-6446
Éditeur: Elsevier BV
DOI: 10.1016/j.drudis.2018.01.019

Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential

Auteurs: Michela Comune, Akhilesh Rai, Kiran K. Chereddy, Sandra Pinto, Sezin Aday, André F. Ferreira, Alessandra Zonari, Josephine Blersch, Rodrigo Cunha, Ricardo Rodrigues, Juan Lerma, Pedro N. Simões, Veronique Préat, Lino Ferreira
Publié dans: Journal of Controlled Release, Numéro 262, 2017, Page(s) 58-71, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2017.07.007

Intracellular delivery of more than one protein with spatio-temporal control

Auteurs: Miguel M. Lino, Susana Simões, Sónia Pinho, Lino Ferreira
Publié dans: Nanoscale, Numéro 9/47, 2017, Page(s) 18668-18680, ISSN 2040-3364
Éditeur: Royal Society of Chemistry
DOI: 10.1039/c7nr02414b

Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules

Auteurs: Adrián Jiménez-Balsa, Sandra Pinto, Emanuel Quartin, Miguel M. Lino, Vitor Francisco, Lino Ferreira
Publié dans: Bioconjugate Chemistry, Numéro 29/5, 2018, Page(s) 1485-1489, ISSN 1043-1802
Éditeur: American Chemical Society
DOI: 10.1021/acs.bioconjchem.7b00820

Substrate Topography Modulates Cell Aging on a Progeria Cell Model

Auteurs: Patricia R. Pitrez, Luís Estronca, Helena Vazão, Anne-Laure Egesipe, Amélie Le Corf, Claire Navarro, Nicolas Lévy, Annachiara De Sandre-Giovannoli, Xavier Nissan, Lino Ferreira
Publié dans: ACS Biomaterials Science & Engineering, 2018, ISSN 2373-9878
Éditeur: American Chemical Society
DOI: 10.1021/acsbiomaterials.8b00224

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

Auteurs: Miguel M. Lino, Susana Simões, Andreia Vilaça, Helena Antunes, Alessandra Zonari, Lino Ferreira
Publié dans: ACS Nano, Numéro 12/6, 2018, Page(s) 5207-5220, ISSN 1936-0851
Éditeur: American Chemical Society
DOI: 10.1021/acsnano.7b07538

A nanoformulation for the preferential accumulation in adult neurogenic niches

Auteurs: Catarina Praça, Akhilesh Rai, Tiago Santos, Ana C. Cristovão, Sonia L. Pinho, Romeo Cecchelli, Marie-Pierre Dehouck, Liliana Bernardino, Lino S. Ferreira
Publié dans: Journal of Controlled Release, Numéro 284, 2018, Page(s) 57-72, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2018.06.013

Biophysical Regulation of Vascular Differentiation and Assembly

Auteurs: Sharon Gerecht
Publié dans: Biological and Medical Physics, Biomedical Engineering, 2018, ISBN 978-3-319-99319-5
Éditeur: Springer International Publishing
DOI: 10.1007/978-3-319-99319-5

Droits de propriété intellectuelle

COMPOSITION FOR RESPONDING TO INFRA-RED LIGHT TO RELEASE BIOMOLECULES AND USES THEREOInventors:CATARINA ARAÚJO GOMES REBELO; SONIA LUZIA CLARO DE PINHO; LINO FERREIRA

Numéro de demande/publication: PAT 20171000067030 COMPOSITION FOR RESPONDING TO INFRA-RED LIGHT TO RELEASE BIOMOLECULES AND USES THEREO
Date: 2017-10-11