Enhancing Research in Ageing at the University of Coimbra

Risultati finali

Publication of ERA Chair team position announcement
Publication of ERA Chair website (phase 2)
ERA Chair laboratory fully operational (phase 1)
Publication of ERA Chair position announcement
Scientific lecture at UC based on main achievements accomplished up to the third year of ERA@UC
Production of ERA Chair leaflet
Public lecture for science awareness on ageing research based on the outcomes of ERA@UC project
Organization of awareness events and press releases about the ERA Chair team research
Identification of key requirements for ERA Chair position announcement
Laboratory fully operational (phase 2)
Publication of ERA Chair website (Phase 1)

Publication of ERA Chair website Phase 1

A one-page statement with the collection of peer-reviewed publications (in the research field of ageing) of the coordinator in high impact journals
ERA Chair Recruitment and Monitoring Team
Selection of ERA Chair collaborators
Report on the selection process of the ERA Chair holder
ERA Chair MIA International Advisory Board
Selection of best candidate for ERA Chair holder
Institutional appointment of ERA Chair holder (provisional, depending on evaluation outcome)
ERA Chair support team in place

Pubblicazioni

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition

Autori: Sezin Aday, Janet Zoldan, Marie Besnier, Laura Carreto, Jaimy Saif, Rui Fernandes, Tiago Santos, Liliana Bernardino, Robert Langer, Costanza Emanueli, Lino Ferreira
Pubblicato in: Nature Communications, Numero 8/1, 2017, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-017-00746-7

Stem cells as vehicles and targets of nanoparticles

Autori: Sonia Pinho, Maria H. Macedo, Catarina Rebelo, Bruno Sarmento, Lino Ferreira
Pubblicato in: Drug Discovery Today, Numero 23/5, 2018, Pagina/e 1071-1078, ISSN 1359-6446
Editore: Elsevier BV
DOI: 10.1016/j.drudis.2018.01.030

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes

Autori: P. José Gouveia, S. Rosa, L. Ricotti, B. Abecasis, H.V. Almeida, L. Monteiro, J. Nunes, F. Sofia Carvalho, M. Serra, S. Luchkin, A. Leonidovitch Kholkin, P. Marques Alves, P. Jorge Oliveira, R. Carvalho, A. Menciassi, R. Pires das Neves, L. Silva Ferreira
Pubblicato in: Biomaterials, Numero 139, 2017, Pagina/e 213-228, ISSN 0142-9612
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2017.05.048

Light-triggerable formulations for the intracellular controlled release of biomolecules

Autori: Miguel M. Lino, Lino Ferreira
Pubblicato in: Drug Discovery Today, Numero 23/5, 2018, Pagina/e 1062-1070, ISSN 1359-6446
Editore: Elsevier BV
DOI: 10.1016/j.drudis.2018.01.019

Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential

Autori: Michela Comune, Akhilesh Rai, Kiran K. Chereddy, Sandra Pinto, Sezin Aday, André F. Ferreira, Alessandra Zonari, Josephine Blersch, Rodrigo Cunha, Ricardo Rodrigues, Juan Lerma, Pedro N. Simões, Veronique Préat, Lino Ferreira
Pubblicato in: Journal of Controlled Release, Numero 262, 2017, Pagina/e 58-71, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2017.07.007

Intracellular delivery of more than one protein with spatio-temporal control

Autori: Miguel M. Lino, Susana Simões, Sónia Pinho, Lino Ferreira
Pubblicato in: Nanoscale, Numero 9/47, 2017, Pagina/e 18668-18680, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/c7nr02414b

Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules

Autori: Adrián Jiménez-Balsa, Sandra Pinto, Emanuel Quartin, Miguel M. Lino, Vitor Francisco, Lino Ferreira
Pubblicato in: Bioconjugate Chemistry, Numero 29/5, 2018, Pagina/e 1485-1489, ISSN 1043-1802
Editore: American Chemical Society
DOI: 10.1021/acs.bioconjchem.7b00820

Substrate Topography Modulates Cell Aging on a Progeria Cell Model

Autori: Patricia R. Pitrez, Luís Estronca, Helena Vazão, Anne-Laure Egesipe, Amélie Le Corf, Claire Navarro, Nicolas Lévy, Annachiara De Sandre-Giovannoli, Xavier Nissan, Lino Ferreira
Pubblicato in: ACS Biomaterials Science & Engineering, 2018, ISSN 2373-9878
Editore: American Chemical Society
DOI: 10.1021/acsbiomaterials.8b00224

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

Autori: Miguel M. Lino, Susana Simões, Andreia Vilaça, Helena Antunes, Alessandra Zonari, Lino Ferreira
Pubblicato in: ACS Nano, Numero 12/6, 2018, Pagina/e 5207-5220, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.7b07538

A nanoformulation for the preferential accumulation in adult neurogenic niches

Autori: Catarina Praça, Akhilesh Rai, Tiago Santos, Ana C. Cristovão, Sonia L. Pinho, Romeo Cecchelli, Marie-Pierre Dehouck, Liliana Bernardino, Lino S. Ferreira
Pubblicato in: Journal of Controlled Release, Numero 284, 2018, Pagina/e 57-72, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2018.06.013

Biophysical Regulation of Vascular Differentiation and Assembly

Autori: Sharon Gerecht
Pubblicato in: Biological and Medical Physics, Biomedical Engineering, 2018, ISBN 978-3-319-99319-5
Editore: Springer International Publishing
DOI: 10.1007/978-3-319-99319-5

Diritti di proprietà intellettuale

COMPOSITION FOR RESPONDING TO INFRA-RED LIGHT TO RELEASE BIOMOLECULES AND USES THEREOInventors:CATARINA ARAÚJO GOMES REBELO; SONIA LUZIA CLARO DE PINHO; LINO FERREIRA

Numero candidatura/pubblicazione: PAT 20171000067030 COMPOSITION FOR RESPONDING TO INFRA-RED LIGHT TO RELEASE BIOMOLECULES AND USES THEREO
Data: 2017-10-11