Publications Peer reviewed articles (13) Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation Auteurs: Allison W McClure; John FX Diffley Publié dans: eLife, Issue 2, 2022, ISSN 2050-084X Éditeur: eLife Sciences Publications DOI: 10.1101/2021.04.09.439171 The mechanism of eukaryotic CMG helicase activation Auteurs: Max E. Douglas, Ferdos Abid Ali, Alessandro Costa, John F. X. Diffley Publié dans: Nature, Issue 555/7695, 2018, Page(s) 265-268, ISSN 0028-0836 Éditeur: Nature Publishing Group DOI: 10.1038/nature25787 Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading Auteurs: Gideon Coster, John F. X. Diffley Publié dans: Science, Issue 357/6348, 2017, Page(s) 314-318, ISSN 0036-8075 Éditeur: American Association for the Advancement of Science DOI: 10.1126/science.aan0063 Cryo-EM structure of a licensed DNA replication origin Auteurs: Ferdos Abid Ali, Max E. Douglas, Julia Locke, Valerie E. Pye, Andrea Nans, John F. X. Diffley, Alessandro Costa Publié dans: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723 Éditeur: Nature Publishing Group DOI: 10.1038/s41467-017-02389-0 How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication Auteurs: Joseph T.P. Yeeles, Agnieska Janska, Anne Early, John F.X. Diffley Publié dans: Molecular Cell, Issue 65/1, 2017, Page(s) 105-116, ISSN 1097-2765 Éditeur: Cell Press DOI: 10.1016/j.molcel.2016.11.017 Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates Auteurs: Christoph F. Kurat, Joseph T.P. Yeeles, Harshil Patel, Anne Early, John F.X. Diffley Publié dans: Molecular Cell, Issue 65/1, 2017, Page(s) 117-130, ISSN 1097-2765 Éditeur: Cell Press DOI: 10.1016/j.molcel.2016.11.016 Cdt1 stabilizes an open MCM ring for helicase loading Auteurs: Jordi Frigola, Jun He, Kerstin Kinkelin, Valerie E. Pye, Ludovic Renault, Max E. Douglas, Dirk Remus, Peter Cherepanov, Alessandro Costa, John F. X. Diffley Publié dans: Nature Communications, Issue 8, 2017, Page(s) 15720, ISSN 2041-1723 Éditeur: Nature Publishing Group DOI: 10.1038/ncomms15720 CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome Auteurs: Jin Chuan Zhou, Agnieszka Janska, Panchali Goswami, Ludovic Renault, Ferdos Abid Ali, Abhay Kotecha, John F. X. Diffley, Alessandro Costa Publié dans: Proceedings of the National Academy of Sciences, Issue 114/16, 2017, Page(s) 4141-4146, ISSN 0027-8424 Éditeur: National Academy of Sciences DOI: 10.1073/pnas.1700530114 Rpd3L Contributes to the DNA Damage Sensitivity of Saccharomyces cerevisiae Checkpoint Mutants Auteurs: Belén Gómez-González, Harshil Patel, Anne Early, John F. X. Diffley Publié dans: Genetics, Issue 211/2, 2019, Page(s) 503-513, ISSN 0016-6731 Éditeur: Genetics Society of America DOI: 10.1534/genetics.118.301817 Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM Auteurs: Thomas C. R. Miller, Julia Locke, Julia F. Greiwe, John F. X. Diffley, Alessandro Costa Publié dans: Nature, Issue 575/7784, 2019, Page(s) 704-710, ISSN 0028-0836 Éditeur: Nature Publishing Group DOI: 10.1038/s41586-019-1768-0 Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome Auteurs: Panchali Goswami, Ferdos Abid Ali, Max E. Douglas, Julia Locke, Andrew Purkiss, Agnieszka Janska, Patrik Eickhoff, Anne Early, Andrea Nans, Alan M. C. Cheung, John F. X. Diffley, Alessandro Costa Publié dans: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723 Éditeur: Nature Publishing Group DOI: 10.1038/s41467-018-07417-1 A DNA replication fork-centric view of the budding yeast DNA damage response Auteurs: Allison W. McClure; Berta Canal; John F.X. Diffley Publié dans: eLife, Issue 2, 2022, ISSN 2050-084X Éditeur: eLife Sciences Publications DOI: 10.25418/crick.21164149 Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitro. Auteurs: Max E. Douglas; John F.X. Diffley Publié dans: Nucleic Acids Research, Issue 1, 2021, ISSN 0305-1048 Éditeur: Oxford University Press DOI: 10.1093/nar/gkab416 Recherche de données OpenAIRE... Une erreur s’est produite lors de la recherche de données OpenAIRE Aucun résultat disponible