Synthetic Cell Biology: Designing organelle transport mechanisms

Project Information

ArtifiCell

Grant agreement ID: 669612

DOI

10.3030/669612

Project closed

EC signature date 30 June 2015

Start date 1 September 2015

End date 31 August 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 3 000 000,00

EU contribution

€ 3 000 000,00

Coordinated by

UNIVERSITY COLLEGE LONDON
United Kingdom

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Freezing and piercing of in vitro asymmetric plasma membrane by α-synuclein

Author(s): Paul Heo, Frederic Pincet
Published in: Communications Biology, Issue 3/1, 2020, ISSN 2399-3642
Publisher: Nature Publishing Group
DOI: 10.1038/s42003-020-0883-7

Nascent fusion pore opening monitored at single-SNAREpin resolution

Author(s): Paul Heo, Jeff Coleman, Jean-Baptiste Fleury, James E. Rothman, Frederic Pincet
Published in: Proceedings of the National Academy of Sciences, Issue 118/5, 2021, Page(s) e2024922118, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2024922118

PRRT2 Regulates Synaptic Fusion by Directly Modulating SNARE Complex Assembly

Author(s): Jeff Coleman, Ouardane Jouannot, Sathish K. Ramakrishnan, Maria N. Zanetti, Jing Wang, Vincenzo Salpietro, Henry Houlden, James E. Rothman, Shyam S. Krishnakumar
Published in: Cell Reports, Issue 22/3, 2018, Page(s) 820-831, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2017.12.056

Vesicle Tubulation with Self-Assembling DNA Nanosprings

Author(s): Michael W. Grome, Zhao Zhang, Frédéric Pincet, Chenxiang Lin
Published in: Angewandte Chemie International Edition, Issue 57/19, 2018, Page(s) 5330-5334, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201800141

Placing and shaping liposomes with reconfigurable DNA nanocages

Author(s): Zhao Zhang, Yang Yang, Frederic Pincet, Marc C. Llaguno, Chenxiang Lin
Published in: Nature Chemistry, Issue 9/7, 2017, Page(s) 653-659, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/NCHEM.2802

High-Throughput Monitoring of Single Vesicle Fusion Using Freestanding Membranes and Automated Analysis

Author(s): Sathish Ramakrishnan, Andrea Gohlke, Feng Li, Jeff Coleman, Weiming Xu, James E. Rothman, Frederic Pincet
Published in: Langmuir, Issue 34/20, 2018, Page(s) 5849-5859, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.8b00116

Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis

Author(s): Oscar D. Bello, Ouardane Jouannot, Arunima Chaudhuri, Ekaterina Stroeva, Jeff Coleman, Kirill E. Volynski, James E. Rothman, Shyam S. Krishnakumar
Published in: Proceedings of the National Academy of Sciences, Issue 115/32, 2018, Page(s) E7624-E7631, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1808792115

SNARE machinery is optimized for ultrafast fusion

Author(s): Fabio Manca, Frederic Pincet, Lev Truskinovsky, James E. Rothman, Lionel Foret, Matthieu Caruel
Published in: Proceedings of the National Academy of Sciences, Issue 116/7, 2019, Page(s) 2435-2442, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1820394116

Highly Reproducible Physiological Asymmetric Membrane with Freely Diffusing Embedded Proteins in a 3D‐Printed Microfluidic Setup

Author(s): Paul Heo, Sathish Ramakrishnan, Jeff Coleman, James E. Rothman, Jean‐Baptiste Fleury, Frederic Pincet
Published in: Small, Issue 15/21, 2019, Page(s) 1900725, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201900725