MASS Spectrometry TRaining network for Protein Lipid adduct ANalysis

Livrables

Network Summer School 1

Summer School Training Event

ESR Recruitment

All ESRs to have been recruited by partners by month12

Network Summer School 2

Summer School Training Event

Database of (lip)oxPTM Fragmentation

Creation of a Database of (lip)oxPTM Fragmentation

Mutant Protein Constructs

Production of mutant protein contructs

Joint Public Engagement Event

Organisation of a joint public engagement event

Database of oxPL/NO2PL Fragmentation

The creation of a Database of oxPL/NO2PL Fragmentation

Database of (lip)oxidation targets

Production of a database of (lip)oxidation targets

Open Conference

Organisation of an open conference

Data Management Plan Agreed

Production of a Data Management Plan

Special Issue on Lipoxidation Targets

Production of an article: Special Issue on Lipoxidation Targets

1st publication All ESRs

Production of 1st publication by all ESRs

Special Issue on Novel MS Methodology

Production of an article: Special Issue on Novel MS Methodology

Joint Training Certificates Awarded

Joint Training Certificates Awarded to ESR's

All ESR projects completed and reports submitted

All ESR practical work completed, reports submitted and draft theses prepared

Final Technical Training Reports

Production of Technical Training Reports

Technical Training Reports

Prodction of Technical Training Reports

Annual Management Reports

Submission of annual management reports

Project Website

MASSTRPLAN project website created and live

Bioinformatics Tool for oxPTMs

Creation of a Bioinformatics Tool for oxPTMs

Set of LC-MS Protocols for ox biomols

Creation of a set of LC-MS Protocols for ox biomols

Bioinformatics Tool for oxPLs

Creation of a Bioinformatics Tool for oxPLs

Protocols for novel chemical labeling

Creation of Protocols for novel chemical labeling

Publications

Drawbacks of Dialysis Procedures for Removal of EDTA

Auteurs: Andreia Mónico, Eva Martínez-Senra, F. Javier Cañada, Silvia Zorrilla, Dolores Pérez-Sala
Publié dans: PLOS ONE, Numéro 12/1, 2017, Page(s) e0169843, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0169843

Electrochemical oxidation of phosphatidylethanolamines studied by mass spectrometry

Auteurs: Simone Colombo, Giulia Coliva, Agnieszka Kraj, Jean-Pierre Chervet, Maria Fedorova, Pedro Domingues, M. Rosário Domingues
Publié dans: Journal of Mass Spectrometry, 2017, ISSN 1076-5174
Éditeur: IM Publications
DOI: 10.1002/jms.4056

Proteomics in cardiovascular diseases: Unveiling sex and gender differences in the era of precision medicine

Auteurs: Roberta Baetta, Marta Pontremoli, Alma Martinez Fernandez, Corinne M. Spickett, Cristina Banfi
Publié dans: Journal of Proteomics, Numéro 173, 2018, Page(s) 62-76, ISSN 1874-3919
Éditeur: Elsevier BV
DOI: 10.1016/j.jprot.2017.11.012

The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization

Auteurs: Álvaro Viedma-Poyatos, Yolanda de Pablo, Milos Pekny, Dolores Pérez-Sala
Publié dans: Free Radical Biology and Medicine, Numéro 120, 2018, Page(s) 380-394, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.04.007

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds

Auteurs: Bebiana C. Sousa, Andrew R. Pitt, Corinne M. Spickett
Publié dans: Free Radical Biology and Medicine, Numéro 111, 2017, Page(s) 294-308, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.02.003

A Novel Lipidomics Workflow for Improved Human Plasma Identification and Quantification Using RPLC-MSn Methods and Isotope Dilution Strategies

Auteurs: Evelyn Rampler, Angela Criscuolo, Martin Zeller, Yasin El Abiead, Harald Schoeny, Gerrit Hermann, Elena Sokol, Ken Cook, David A. Peake, Bernard Delanghe, Gunda Koellensperger
Publié dans: Analytical Chemistry, Numéro 90/11, 2018, Page(s) 6494-6501, ISSN 0003-2700
Éditeur: American Chemical Society
DOI: 10.1021/acs.analchem.7b05382

Phospholipidome of endothelial cells shows a different adaptation response upon oxidative, glycative and lipoxidative stress

Auteurs: Simone Colombo, Tânia Melo, Marta Martínez-López, M. Jesús Carrasco, M. Rosário Domingues, Dolores Pérez-Sala, Pedro Domingues
Publié dans: Scientific Reports, Numéro 8/1, 2018, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-018-30695-0

PARP1 promoter links cell cycle progression with adaptation to oxidative environment

Auteurs: Julita Pietrzak, Corinne M. Spickett, Tomasz Płoszaj, László Virág, Agnieszka Robaszkiewicz
Publié dans: Redox Biology, Numéro 18, 2018, Page(s) 1-5, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2018.05.017

Impact of inhibition of the autophagy-lysosomal pathway on biomolecules carbonylation and proteome regulation in rat cardiac cells

Auteurs: Giulia Coliva, Sofia Duarte, Dolores Pérez-Sala, Maria Fedorova
Publié dans: Redox Biology, 2019, Page(s) 101123, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2019.101123

Comprehensive and Empirical Evaluation of Machine Learning Algorithms for Small Molecule LC Retention Time Prediction

Auteurs: Robbin Bouwmeester, Lennart Martens, Sven Degroeve
Publié dans: Analytical Chemistry, Numéro 91/5, 2019, Page(s) 3694-3703, ISSN 0003-2700
Éditeur: American Chemical Society
DOI: 10.1021/acs.analchem.8b05820

Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions

Auteurs: Silvia Zorrilla, Andreia Mónico, Sofia Duarte, Germán Rivas, Dolores Pérez-Sala, María A. Pajares
Publié dans: Free Radical Biology and Medicine, 2019, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.04.011

Functional Impairment of Circulating FcεRI + Monocytes and Myeloid Dendritic Cells in Hepatocellular Carcinoma and Cholangiocarcinoma Patients

Auteurs: Carmen Martín-Sierra, Ricardo Martins, Paula Laranjeira, A. Margarida Abrantes, R. Caetano Oliveira, J. Guilherme Tralhão, M. Filomena Botelho, Emanuel Furtado, Rosário Domingues, Artur Paiva
Publié dans: Cytometry Part B: Clinical Cytometry, 2019, ISSN 1552-4949
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/cyto.b.21777

Modulation of the inflammatory response of immune cells in human peripheral blood by oxidized arachidonoyl aminophospholipids

Auteurs: Simone Colombo, Carmen Martín-Sierra, Tânia Melo, Paula Laranjeira, Artur Paiva, Pedro Domingues, M. Rosário Domingues
Publié dans: Archives of Biochemistry and Biophysics, Numéro 660, 2018, Page(s) 64-71, ISSN 0003-9861
Éditeur: Academic Press
DOI: 10.1016/j.abb.2018.10.003

Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes

Auteurs: Alma Martinez Fernandez, Luca Regazzoni, Maura Brioschi, Erica Gianazza, Piergiuseppe Agostoni, Giancarlo Aldini, Cristina Banfi
Publié dans: Free Radical Biology and Medicine, 2019, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.06.023

Advanced lipoxidation end products (ALEs) as RAGE binders: Mass spectrometric and computational studies to explain the reasons why

Auteurs: Marco Mol, Genny Degani, Crescenzo Coppa, Giovanna Baron, Laura Popolo, Marina Carini, Giancarlo Aldini, Giulio Vistoli, Alessandra Altomare
Publié dans: Redox Biology, 2018, Page(s) 101083, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2018.101083

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division

Auteurs: Sofia Duarte, Álvaro Viedma-Poyatos, Elena Navarro-Carrasco, Alma E. Martínez, María A. Pajares, Dolores Pérez-Sala
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-019-12029-4

A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine

Auteurs: Leanne C. Nye, Jonathan P. Williams, Nyasha C. Munjoma, Marine P.M. Letertre, Muireann Coen, Robbin Bouwmeester, Lennart Martens, Jonathan R. Swann, Jeremy K. Nicholson, Robert S. Plumb, Michael McCullagh, Lee A. Gethings, Steven Lai, James I. Langridge, Johannes P.C. Vissers, Ian D. Wilson
Publié dans: Journal of Chromatography A, Numéro 1602, 2019, Page(s) 386-396, ISSN 0021-9673
Éditeur: Elsevier BV
DOI: 10.1016/j.chroma.2019.06.056

Accurate peptide fragmentation predictions allow data driven approaches to replace and improve upon proteomics search engine scoring functions

Auteurs: Ana S C Silva, Robbin Bouwmeester, Lennart Martens, Sven Degroeve
Publié dans: Bioinformatics, 2019, ISSN 1367-4803
Éditeur: Oxford University Press
DOI: 10.1093/bioinformatics/btz383

Enzymatic and non-enzymatic detoxification of 4-hydroxynonenal: Methodological aspects and biological consequences

Auteurs: Marco Mol, Luca Regazzoni, Alessandra Altomare, Genny Degani, Marina Carini, Giulio Vistoli, Giancarlo Aldini
Publié dans: Free Radical Biology and Medicine, 2017, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.01.036

Exercise training counteracts urothelial carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model

Auteurs: Javier-Fernando Montero-Bullon, Tânia Melo, Rita Ferreira, Ana Isabel Padrão, Paula A. Oliveira, M. Rosário M. Domingues, Pedro Domingues
Publié dans: Scientific Reports, Numéro 9/1, 2019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-019-49010-6

Characterization of Nitrophospholipid-Peptide Covalent Adducts by Electrospray Tandem Mass Spectrometry: A First Screening Analysis Using Different Instrumental Platforms

Auteurs: Javier-Fernando Montero-Bullon, Tânia Melo, Maria Rosário Domingues, Pedro Domingues
Publié dans: European Journal of Lipid Science and Technology, Numéro 120/12, 2018, Page(s) 1800101, ISSN 1438-7697
Éditeur: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/ejlt.201800101

Lipoproteins as targets and markers of lipoxidation

Auteurs: Catarina B. Afonso, Corinne M. Spickett
Publié dans: Redox Biology, Numéro 23, 2019, Page(s) 101066, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2018.101066

Analysis of oxidised and glycated aminophospholipids: Complete structural characterisation by C30 liquid chromatography-high resolution tandem mass spectrometry

Auteurs: Simone Colombo, Angela Criscuolo, Martin Zeller, Maria Fedorova, M. Rosário Domingues, Pedro Domingues
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 144-155, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.05.025

Lipoxidation and cancer immunity

Auteurs: C. Martín-Sierra, P. Laranjeira, M.R. Domingues, A. Paiva
Publié dans: Redox Biology, Numéro 23, 2019, Page(s) 101103, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2019.101103

Insight into the cellular effects of nitrated phospholipids: Evidence for pleiotropic mechanisms of action

Auteurs: Sofia Duarte, Tânia Melo, Rosário Domingues, Juan de Dios Alché, Dolores Pérez-Sala
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 192-202, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.06.003

Liquid chromatography/tandem mass spectrometry characterization of nitroso, nitrated and nitroxidized cardiolipin products

Auteurs: Javier-Fernando Montero-Bullon, Tânia Melo, M. Rosário M Domingues, Pedro Domingues
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 183-191, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.05.009

Computational solutions in redox lipidomics – Current strategies and future perspectives

Auteurs: Zhixu Ni, Laura Goracci, Gabriele Cruciani, Maria Fedorova
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 110-123, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.04.027

Functional and Phenotypic Characterization of Tumor-Infiltrating Leukocyte Subsets and Their Contribution to the Pathogenesis of Hepatocellular Carcinoma and Cholangiocarcinoma

Auteurs: C. Martín-Sierra, R. Martins, P. Laranjeira, M. Coucelo, A.M. Abrantes, R.C. Oliveira, J.G. Tralhão, M.F. Botelho, E. Furtado, M.R. Domingues, A. Paiva
Publié dans: Translational Oncology, Numéro 12/11, 2019, Page(s) 1468-1479, ISSN 1936-5233
Éditeur: Neoplasia Press
DOI: 10.1016/j.tranon.2019.07.019

Lipoxidation in cardiovascular diseases

Auteurs: Erica Gianazza, Maura Brioschi, Alma Martinez Fernandez, Cristina Banfi
Publié dans: Redox Biology, Numéro 23, 2019, Page(s) 101119, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2019.101119

Discovery of bioactive nitrated lipids and nitro-lipid-protein adducts using mass spectrometry-based approaches

Auteurs: Tânia Melo, Javier-Fernando Montero-Bullón, Pedro Domingues, M. Rosário Domingues
Publié dans: Redox Biology, Numéro 23, 2019, Page(s) 101106, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2019.101106

Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS

Auteurs: Zhixu Ni, Bebiana C. Sousa, Simone Colombo, Catarina B. Afonso, Tania Melo, Andrew R. Pitt, Corinne M. Spickett, Pedro Domingues, M. Rosário Domingues, Maria Fedorova, Angela Criscuolo
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 156-166, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.06.013

Lipoxidation targets: From basic mechanisms to pathophysiology

Auteurs: Dolores Pérez-Sala, Rosário Domingues
Publié dans: Redox Biology, Numéro 23, 2019, Page(s) 101208, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2019.101208

Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies

Auteurs: Isabel Campos-Pinto, Lucía Méndez, James Schouten, John Wilkins, Maria Fedorova, Andrew R. Pitt, Paul Davis, Corinne M. Spickett
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 234-244, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.05.008

Cracking Proteoform Complexity of Ovalbumin with Anion-Exchange Chromatography–High-Resolution Mass Spectrometry under Native Conditions

Auteurs: Florian Füssl, Angela Criscuolo, Ken Cook, Kai Scheffler, Jonathan Bones
Publié dans: Journal of Proteome Research, Numéro 18/10, 2019, Page(s) 3689-3702, ISSN 1535-3893
Éditeur: American Chemical Society
DOI: 10.1021/acs.jproteome.9b00375

Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells

Auteurs: Bebiana C. Sousa, Tanzim Ahmed, William L. Dann, Jed Ashman, Alexandre Guy, Thierry Durand, Andrew R. Pitt, Corinne M. Spickett
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 223-233, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.05.028

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

Auteurs: Andreia Mónico, Sofia Duarte, María A. Pajares, Dolores Pérez-Sala
Publié dans: Redox Biology, Numéro 23, 2019, Page(s) 101098, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2019.101098

Mass spectrometry strategies to unveil modified aminophospholipids of biological interest

Auteurs: Simone Colombo, Pedro Domingues, M. Rosário Domingues
Publié dans: Mass Spectrometry Reviews, Numéro 38/4-5, 2019, Page(s) 323-355, ISSN 0277-7037
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/mas.21584

A mass spectrometry approach for the identification and localization of small aldehyde modifications of proteins

Auteurs: Catarina B. Afonso, Bebiana C. Sousa, Andrew R. Pitt, Corinne M. Spickett
Publié dans: Archives of Biochemistry and Biophysics, Numéro 646, 2018, Page(s) 38-45, ISSN 0003-9861
Éditeur: Academic Press
DOI: 10.1016/j.abb.2018.03.026

Rational selection of reverse phase columns for high throughput LC–MS lipidomics

Auteurs: Angela Criscuolo, Martin Zeller, Ken Cook, Georgia Angelidou, Maria Fedorova
Publié dans: Chemistry and Physics of Lipids, Numéro 221, 2019, Page(s) 120-127, ISSN 0009-3084
Éditeur: Elsevier BV
DOI: 10.1016/j.chemphyslip.2019.03.006

Liquid Chromatography Techniques in Lipidomics Research

Auteurs: Mike Lange, Zhixu Ni, Angela Criscuolo, Maria Fedorova
Publié dans: Chromatographia, Numéro 82/1, 2019, Page(s) 77-100, ISSN 0009-5893
Éditeur: Elsevier BV
DOI: 10.1007/s10337-018-3656-4

Oxidized phosphatidylserine mitigates LPS-triggered macrophage inflammatory status through modulation of JNK and NF-kB signaling cascades

Auteurs: Elisabete Maciel, Bruno M. Neves, João Martins, Simone Colombo, Maria Teresa Cruz, Pedro Domingues, M. Rosário M. Domingues
Publié dans: Cellular Signalling, Numéro 61, 2019, Page(s) 30-38, ISSN 0898-6568
Éditeur: Elsevier BV
DOI: 10.1016/j.cellsig.2019.04.015

Exploring the biochemistry of the prenylome and its role in disease through proteomics: progress and potential

Auteurs: Maura Brioschi, Alma Martinez Fernandez, Cristina Banfi
Publié dans: Expert Review of Proteomics, Numéro 14/6, 2017, Page(s) 515-528, ISSN 1478-9450
Éditeur: Future Drugs Ltd.
DOI: 10.1080/14789450.2017.1332998

Modification of cysteine residues by cyclopentenone prostaglandins in the elucidation of redox regulation of protein function

Auteurs: Dolores Pérez Sala
Publié dans: Toxicology Letters, Numéro 258, 2016, Page(s) S44, ISSN 0378-4274
Éditeur: Elsevier BV
DOI: 10.1016/j.toxlet.2016.06.1259

Oxidative modifications cross-talk in redox regulation of cellular physiology

Auteurs: Eva Griesser, Giulia Coliva, Andreia Mónico, Dolores Pérez-Sala, Maria Fedorova
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S47, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.171

Characterization of vimentin-zinc interaction and its impact on the response to electrophilic and oxidative stress

Auteurs: Andreia Mónico, Silvia Zorrilla, Dolores Pérez-Sala
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S46, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.170

Interaction of nitrated/nitroxidized phospholipids with vimentin

Auteurs: Tania Melo, Sofia Duarte, Pedro Domingues, Rosario M Domingues, Dolores Pérez-Sala
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S52, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.187

A mass spectrometry approach for the identification and localization of acrolein modifications of proteins

Auteurs: Bebiana C. Sousa, Corinne M. Spickett, Andrew R. Pitt
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S54, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.192

Identification and localization of protein-pentanal adducts, a potential lipoxidation marker

Auteurs: Catarina Afonso, Andrew R. Pitt, Corinne M. Spickett
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S54, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.193

Alteration of phospholipidome profile in the heart of an animal model of acute myocardial infarction

Auteurs: Javier Fernando Montero Bullón, Tania Melo, Tania Martins-Marques, Henrique Girão, Rosário Domingues, Pedro Domingues
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S61, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.214

Aminophospholipid oxidation and glycation in immunity: good or bad?

Auteurs: Rosário Domingues, Tania Melo, Elisabete Maciel, Simone Colombo, Pedro Domingues
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S61, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.211

Oxidative metabolism of phosphatidylethanolamines predicted by electrochemistry-mass spectrometry

Auteurs: Simone Colombo, Giulia Coliva, Agnieszka Kraj, Jean-Pierre Chervet, Maria Fedorova, Pedro Domingues, M. Rosario Domingues
Publié dans: Free Radical Biology and Medicine, Numéro 108, 2017, Page(s) S62, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.04.215

Effects of oxidants and electrophiles on vimentin assembly

Auteurs: Andreia Mónico, Sofia Duarte, Maria A. Pajares, Dolores Pérez-Sala
Publié dans: Free Radical Biology and Medicine, Numéro 120, 2018, Page(s) S69, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.04.227

The conserved cysteine residue of type III intermediate filaments serves as a structural element and redox sensor

Auteurs: Sofia Duarte, Álvaro Viedma-Poyatos, Andreia Mónico, Dolores Pérez-Sala
Publié dans: Free Radical Biology and Medicine, Numéro 120, 2018, Page(s) S84, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.04.277

Radical induced oxidation of di-oleoyl phosphatidylserine using mass spectrometry revealed preferential oxydation of Sn-2 oleoyl chain

Auteurs: M. Rosário Domingues, Ana Campos, Simone Colombo, Tânia Melo, Pedro Domingues
Publié dans: Free Radical Biology and Medicine, Numéro 120, 2018, Page(s) S118, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.04.390

Study of covalent adduction of nitrated phospholipids to peptides using tandem mass spectrometry in different instruments

Auteurs: Javier-Fernando Montero-Bullón, Tânia Melo, M Rosário M Domingues, Pedro Domingues
Publié dans: Free Radical Biology and Medicine, Numéro 120, 2018, Page(s) S121, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.04.399

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

Auteurs: Javier Egea, Isabel Fabregat, Yves M. Frapart, Pietro Ghezzi, Agnes Görlach, Thomas Kietzmann, Kateryna Kubaichuk, Ulla G. Knaus, Manuela G. Lopez, Gloria Olaso-Gonzalez, Andreas Petry, Rainer Schulz, Jose Vina, Paul Winyard, Kahina Abbas, Opeyemi S. Ademowo, Catarina B. Afonso, Ioanna Andreadou, Haike Antelmann, Fernando Antunes, Mutay Aslan, Markus M. Bachschmid, Rui M. Barbosa, Vsevolod Belous
Publié dans: Redox Biology, Numéro 13, 2017, Page(s) 94-162, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2017.05.007

Redox lipidomics and adductomics - Advanced analytical strategies to study oxidized lipids and lipid-protein adducts

Auteurs: Gabriele Cruciani, Pedro Domingues, Maria Fedorova, Francesco Galli, Corinne M. Spickett
Publié dans: Free Radical Biology and Medicine, Numéro 144, 2019, Page(s) 1-5, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2019.07.027

Single Cell Analysis by High-Resolution Atmospheric-Pressure MALDI MS Imaging

Auteurs: Dhaka Ram Bhandari, Giulia Coliva, Maria Fedorova, Bernhard Spengler
Publié dans: Single Cell Metabolism - Methods and Protocols, Numéro 2064, 2020, Page(s) 103-111, ISBN 978-1-4939-9829-6
Éditeur: Springer New York
DOI: 10.1007/978-1-4939-9831-9_8

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