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European Sepsis Academy: towards new biomarkers to improve sepsis management

Objective

ESA-ITN will break through the state of the art in sepsis diagnostics and will train 15 early-stage researchers (ESRs) to
determine the clinical potency of a variety of new complementary sepsis biomarkers. These cover the full range of the antiinflammatory response in sepsis, at genetic, molecular and cellular level. Rapid and practical biomarker diagnostics for
sepsis will be developed by building on some of the world's most innovative diagnostic platforms. In addition, a whole new
clinical research model that incorporates use of biomarker diagnostics will be designed and tested.

All 15 interlinked ESR projects have an interdisciplinary component (intersection of sepsis research, product development,
economics and medical practice) and international (representing 10 countries) and industry collaborations (incorporating 3
diagnostics firms, 1 bioinformatics company and a business school). Interactions within the network are strengthened by
meaningful secondments, which take place at private beneficiary or partner institutes.

The training programme covers:
1. Specialist training in an international, interdisciplinary and intersectorial sepsis-orientated research project;
2. Advanced technology training in pathogenesis, biomarker discovery, diagnostics, trial design and innovation management;
3. Professional training in transferable skills, including the special ESA-ITN mini-MBA.

The setup of ESA-ITN is unique as it reflects the entire innovation value chain for sepsis biomarker diagnostics. ESA-ITN is
composed of leading institutes in sepsis research and a selection of Europe's top biomarker diagnostics companies. Links to
various global networks and shared research infrastructures in the field of sepsis further leverage the proposition of ESA-ITN.

Coordinator

AMC MEDICAL RESEARCH BV
Net EU contribution
€ 766 122,84
Address
Meibergdreef 9
1105AZ Amsterdam Zuidoost
Netherlands

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Participants (7)

HUMANITAS MIRASOLE SPA
Italy
Net EU contribution
€ 516 122,64
Address
Via Manzoni 56
20100 Rozzano (Mi)

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Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
BIOMERIEUX SA
France
Net EU contribution
€ 525 751,20
Address
Chemin De L'orme
69280 Marcy L'etoile

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Region
Auvergne-Rhône-Alpes Rhône-Alpes Rhône
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
INSTITUT EUROPEEN D ADMINISTRATION DES AFFAIRES
France
Net EU contribution
€ 525 751,20
Address
Boulevard De Constance 903f
77305 Fontainebleau Cedex

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Region
Ile-de-France Ile-de-France Seine-et-Marne
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON
Greece
Net EU contribution
€ 484 773,84
Address
6 Christou Lada Str
10561 Athina

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Region
Αττική Aττική Κεντρικός Τομέας Αθηνών
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSITY COLLEGE LONDON
United Kingdom
Net EU contribution
€ 546 575,76
Address
Gower Street
WC1E 6BT London

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
Switzerland
Net EU contribution
€ 530 453,52
Address
Rue Du Bugnon 21
1011 Lausanne

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Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 0,00
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM

Participation ended

Netherlands
Net EU contribution
€ 0,00
Address
Meibergdreef 15
1105AZ Amsterdam
Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00