Nanomedicine: an integrative approach

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Prizes

ESR-ITN prizes (best presentation, best publication, best expose for lay public.

Certificates

ESR Certificates of research-specific/complementary training granted to ESRs.

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Publications

Refining the Design of Diblock Elastin-Like Polypeptides for Self-Assembly into Nanoparticles

Author(s): Michèle Dai; Evangelos Georgilis; Guillaume Goudounet; Bertrand Garbay; Jan Pille; Jan C. M. van Hest; Xavier Schultze; Elisabeth Garanger; Sébastien Lecommandoux
Published in: Polymers, 2021, ISSN 2073-4360
Publisher: MDPI
DOI: 10.3390/polym13091470

Tuning Size and Morphology of mPEG-b-p(HPMA-Bz) Copolymer Self-Assemblies Using Microfluidics

Author(s): Bresseleers, J, Bagheri, M, Lebleu, C, Lecommandoux, S, Sandre, O, Pijpers, IAB, Mason, AF, Meeuwissen, S., van Nostrum, C., Hennink, WE, van Hest, JCM
Published in: Polymers, 2020, ISSN 2073-4360
Publisher: MDPI
DOI: 10.3390/polym12112572

Wormlike Nanovector with Enhanced Drug Loading Using Blends of Biodegradable Block Copolymers

Author(s): Ridolfo, R, Arends, JJ, van Hest, JCM , Williams, DS
Published in: Biomacromolecules, 2020, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.0c00169

Ocular barriers to retinal delivery of intravitreal liposomes: Impact of vitreoretinal interface

Author(s): Shirin Tavakoli, Karen Peynshaert, Tatu Lajunen, Joke Devoldere, Eva M del Amo, Marika Ruponen, Stefaan de Smedt, Katrien Remaut, Arto Urtti
Published in: Journal of controlled release, 2020, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2020.10.028

Size-tunable nanoneedle arrays for influencing stem cell morphology, gene expression and nuclear membrane curvature

Author(s): Seong, H, Higgins, SG, Penders, J, Armstrong, JPK, Crowder, SW, Moore, AC, Sero, JE, Becce, M, Stevens, MM
Published in: ACS Nano, 2020, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.9b08689

Cationic Amphiphilic Drugs Boost the Lysosomal Escape of Small Nucleic Acid Therapeutics in a Nanocarrier-Dependent Manner

Author(s): Thijs Van de Vyver, Bram Bogaert, Lynn De Backer, Freya Joris, Roberta Guagliardo, Jelter Van Hoeck, Pieterjan Merckx, Serge Van Calenbergh, Srinivas Ramishetti, Dan Peer, Katrien Remaut, Stefaan C De Smedt, Koen Raemdonck
Published in: ACS Nano, 2020, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.0c00666

Photoactivated Polymersome Nanomotors: Traversing Biological Barriers

Author(s): Jingxin Shao, Shoupeng Cao, D.S. Williams, LKEA Abdelmohsen, Jan C.M. van Hest
Published in: Angewandte Chemie Int Ed, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202003748

Assessing the impact of silicon nanowires on bacterial transformation and viability of Escherichia coli

Author(s): Becce, M,Kloeckner, A, Higgins, S, Penders, J, Hachim Diaz, DJ, Bashor, CJ, Edwards, A, Stevens, M
Published in: Journal of Materials Chemistry B, 2021, ISSN 2050-750X
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0tb02762f

Light-Activated Liposomes Coated with Hyaluronic Acid as a Potential Drug Delivery System

Author(s): Otto K Kari; Shirin Tavakoli; Petteri Parkkila;Simone Baan; Roosa Savolainen; Teemu Ruoslahti; Niklas G Johansson; Joseph Ndika; Harri Alenius; Tapani Viitala; Arto Urtti; Tatu Lajunen
Published in: Pharmaceutics, 2020, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12080763

Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling

Author(s): Conor C Horgan, Anika Nagelkerke, Thomas E Whittaker, Valeria Nele, Lucia Massi, Ulrike Kauscher, Jelle Penders, Mads S Bergholt, Steve R Hood, Molly M Stevens
Published in: JOURNAL OF MATERIALS CHEMISTRY B, 2020, ISSN 2050-750X
Publisher: ROYAL SOC CHEMISTRY
DOI: 10.1039/d0tb00620c

Biodegradable Polymersomes with Structure Inherent Fluorescence and Targeting Capacity for Enhanced Photo-Dynamic Therapy

Author(s): S. Cao, Y. Xia, J. Shao, B. Guo,Y. Dong, IAB Pijpers, Z. Zhong, F. Meng, LKEA Abdelmohsen, D.S. Williams, Jan C.M. van Hest
Published in: Angewandte Chemie int ed, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202105103

High pressure nebulization (PIPAC) versus injection for the intraperitoneal administration of mRNA complexes

Author(s): Shariati, Molood; Zhang, Heyang; Van de Sande, Leen; Descamps, Benedicte; Vanhove, Chris; Willaert, Wouter; Ceelen, Wim; De Smedt, Stefaan C.; Remaut, Katrien
Published in: PHARMACEUTICAL RESEARCH, 2019, ISSN 0724-8741
Publisher: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11095-019-2646-z

Therapeutic Stomatocytes with Aggregation Induced Emission for Intracellular Delivery

Author(s): Shao, JX, Cao, SP, Wu, HL, Abdelmohsen, LKEA, van Hest, JCM
Published in: PHARMACEUTICS, 2021, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13111833

Influence of surface charge on the formulation of elongated PEG-b-PDLLA nanoparticles

Author(s): Roxane Ridolfo; David S. Williams; Jan C. M. van Hest
Published in: Polymer Chemistry, Issue 14, 2020, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0py00280a

In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

Author(s): Håkon Høgset, Conor C Horgan, James P K Armstrong, Mads S Bergholt, Vincenzo Torraca, Qu Chen, Timothy J Keane, Laurence Bugeon, Margaret J Dallman, Serge Mostowy, Molly M Stevens
Published in: Nature Communications, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-19827-1

Compartmentalized cross-linked enzymatic nano-aggregates (c-CLEnA) for efficient in-flow biocatalysis

Author(s): M. Teresa De Martino; Fabio Tonin; N. Amy Yewdall; Mona Abdelghani; David S. Williams; Ulf Hanefeld; Floris P. J. T. Rutjes; Loai K. E. A. Abdelmohsen; Jan C. M. van Hest
Published in: Chemical Science, 11, 2765 - 2769, Issue 18, 2020, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sc05420k

Self-Assembly or Coassembly of Multiresponsive Histidine-Containing Elastin-Like Polypeptide Block Copolymers

Author(s): Abdelghani, M, Shao, JX, Le, DHT, Wu, HL, van Hest, JCM
Published in: Macromolecular Bioscience, 2021, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202100081

Porous silicon nanoneedles modulate endocytosis to deliver biological payloads

Author(s): Gopal, S, Chiappini, C, Penders, J, Leonardo, V, Seong, H, Rothery, S, Korchev, Y, Shevchuk, A, Stevens, MM
Published in: Advanced Materials, 2019, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201806788

Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region

Author(s): Junnuthula, V, Boroujeni, AS, Cao, SP, Tavakoli, S, Ridolfo, R, Toropainen, E, Ruponen, M ,van Hest, JCM , Urtti, A
Published in: Pharmaceutics, 2021, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13040445

Gold nanocluster extracellular vesicle supraparticles: Self-assembled nanostructures for 3D uptake visualization

Author(s): Kauscher, U; Pender,s J; Nagelkerke, A; Holme, M; Nele, V; Massi, L; Gopal, S; Whittaker, T; Stevens, M
Published in: Langmuir, 2020, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.9b03479

Programming supramolecular peptide materials by modulating the intermediate steps in the complex assembly pathway: Implications for biomedical applications

Author(s): Chun Yin Jerry Lau; Enrico Mastrobattista
Published in: CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 2021, ISSN 1359-0294
Publisher: Pergamon Press
DOI: 10.1016/j.cocis.2020.101396

Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis — Mission possible?

Author(s): George R. Dakwar, Molood Shariati, Wouter Willaert, Wim Ceelen, Stefaan C. De Smedt, Katrien Remaut
Published in: Advanced Drug Delivery Reviews, Issue 108, 2017, Page(s) 13-24, ISSN 0169-409X
Publisher: Elsevier BV
DOI: 10.1016/j.addr.2016.07.001

Feedback-Induced Temporal Control of “Breathing” Polymersomes To Create Self-Adaptive Nanoreactors

Author(s): Hailong Che, Shoupeng Cao, Jan C. M. van Hest
Published in: Journal of the American Chemical Society, Issue 140/16, 2018, Page(s) 5356-5359, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.8b02387

Erythrocyte Membrane Modified Janus Polymeric Motors for Thrombus Therapy

Author(s): Jingxin Shao, Mona Abdelghani, Guizhi Shen, Shoupeng Cao, David S. Williams, Jan C. M. van Hest
Published in: ACS Nano, Issue 12/5, 2018, Page(s) 4877-4885, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.8b01772

Adaptive Polymersome and Micelle Morphologies in Anticancer Nanomedicine: From Design Rationale to Fabrication and Proof‐of‐Concept Studies

Author(s): Imke A. B. Pijpers, Loai K. E. A. Abdelmohsen, Yifeng Xia, Shoupeng Cao, David S. Williams, Fenghua Meng, Jan C. M. Hest, Zhiyuan Zhong
Published in: ADVANCED THERAPEUTICS, Issue 1/8, 2018, Page(s) 1800068, ISSN 2366-3987
Publisher: Wiley
DOI: 10.1002/adtp.201800068

Effect of Formulation and Processing Parameters on the Size of mPEG- b -p(HPMA-Bz) Polymeric Micelles

Author(s): Mahsa Bagheri, Jaleesa Bresseleers, Aida Varela-Moreira, Olivier Sandre, Silvie A. Meeuwissen, Raymond M. Schiffelers, Josbert M. Metselaar, Cornelus F. van Nostrum, Jan C. M. van Hest, Wim E. Hennink
Published in: Langmuir, Issue 34/50, 2018, Page(s) 15495-15506, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.8b03576

Biodegradable, Drug-Loaded Nanovectors via Direct Hydration as a New Platform for Cancer Therapeutics

Author(s): Roxane Ridolfo, Benjamin C. Ede, Paraskevi Diamanti, Paul B. White, Adam W. Perriman, Jan C. M. van Hest, Allison Blair, David S. Williams
Published in: Small, Issue 14/32, 2018, Page(s) 1703774, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201703774

pH-Induced Transformation of Biodegradable Multilamellar Nanovectors for Enhanced Tumor Penetration

Author(s): Shoupeng Cao, Loai K. E. A. Abdelmohsen, Jingxin Shao, Joep van den Dikkenberg, Enrico Mastrobattista, David S. Williams, Jan C. M. van Hest
Published in: ACS Macro Letters, Issue 7/11, 2018, Page(s) 1394-1399, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.8b00807

Biomorphic Engineering of Multifunctional Polylactide Stomatocytes toward Therapeutic Nano-Red Blood Cells

Author(s): Jingxin Shao, Imke A. B. Pijpers, Shoupeng Cao, David S. Williams, Xuehai Yan, Junbai Li, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Published in: Advanced Science, Issue 6/5, 2019, Page(s) 1801678, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.201801678

Single enzyme loaded nanoparticles for combinational ultrasound-guided focused ultrasound ablation and hypoxia-relieved chemotherapy

Author(s): Jianzhi Zhu, Zhicong Li, Changchang Zhang, Lizhou Lin, Shoupeng Cao, Hailong Che, Xiangyang Shi, Han Wang, Jan C. M. van Hest
Published in: Theranostics, Issue 9/26, 2019, Page(s) 8048-8060, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.37054

Molecular Programming of Biodegradable Nanoworms via Ionically Induced Morphology Switch toward Asymmetric Therapeutic Carriers

Author(s): Shoupeng Cao, Jingxin Shao, Yifeng Xia, Hailong Che, Zhiyuan Zhong, Fenghua Meng, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen, David S. Williams
Published in: Small, Issue 15/38, 2019, Page(s) 1901849, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201901849

ATP-Mediated Transient Behavior of Stomatocyte Nanosystems

Author(s): Hailong Che, Jianzhi Zhu, Shidong Song, Alexander F. Mason, Shoupeng Cao, Imke A. B. Pijpers, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Published in: Angewandte Chemie International Edition, Issue 58/37, 2019, Page(s) 13113-13118, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201906331

Adaptive Polymeric Assemblies for Applications in Biomimicry and Nanomedicine

Author(s): Yigit Altay, Shoupeng Cao, Hailong Che, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Published in: Biomacromolecules, Issue 20/11, 2019, Page(s) 4053-4064, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.9b01341

Nucleic acid delivery to differentiated retinal pigment epithelial cells using cell-penetrating peptide as a carrier

Author(s): Bano Subia, Mika Reinisalo, Namit Dey, Shirin Tavakoli, Astrid Subrizi, Munia Ganguli, Marika Ruponen
Published in: European Journal of Pharmaceutics and Biopharmaceutics, Issue 140, 2019, Page(s) 91-99, ISSN 0939-6411
Publisher: Elsevier BV
DOI: 10.1016/j.ejpb.2019.05.003

Nanocarrier Lipid Composition Modulates the Impact of Pulmonary Surfactant Protein B (SP-B) on Cellular Delivery of siRNA

Author(s): Roberta Guagliardo, Pieterjan Merckx, Agata Zamborlin, Lynn De Backer, Mercedes Echaide, Jesus Pérez-Gil, Stefaan C. De Smedt, Koen Raemdonck
Published in: Pharmaceutics, Issue 11/9, 2019, Page(s) 431, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11090431

Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy

Author(s): Pieterjan Merckx, Lynn De Backer, Lien Van Hoecke, Roberta Guagliardo, Mercedes Echaide, Pieter Baatsen, Bárbara Olmeda, Xavier Saelens, Jésus Pérez-Gil, Stefaan C. De Smedt, Koen Raemdonck
Published in: Acta Biomaterialia, Issue 78, 2018, Page(s) 236-246, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2018.08.012

mRNA Polyplexes with Post-Conjugated GALA Peptides Efficiently Target, Transfect, and Activate Antigen Presenting Cells

Author(s): Bo Lou, Stefaan De Koker, Chun Yin Jerry Lau, Wim E. Hennink, Enrico Mastrobattista
Published in: Bioconjugate Chemistry, Issue 30/2, 2018, Page(s) 461-475, ISSN 1043-1802
Publisher: American Chemical Society
DOI: 10.1021/acs.bioconjchem.8b00524

In vivo biocompatibility and immunogenicity of metal–phenolic gelation

Author(s): Mattias Björnmalm, Lok Man Wong, Jonathan P. Wojciechowski, Jelle Penders, Conor C. Horgan, Marsilea A. Booth, Nicholas G. Martin, Susanne Sattler, Molly M. Stevens
Published in: Chemical Science, Issue 10/43, 2019, Page(s) 10179-10194, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sc03325d

Cationic synthetic long peptides-loaded nanogels: An efficient therapeutic vaccine formulation for induction of T-cell responses

Author(s): Neda Kordalivand, Elena Tondini, Chun Yin Jerry Lau, Tina Vermonden, Enrico Mastrobattista, Wim E. Hennink, Ferry Ossendorp, Cornelus F. van Nostrum
Published in: Journal of Controlled Release, Issue 315, 2019, Page(s) 114-125, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.10.048

Aerosolization of Nanotherapeutics as a Newly Emerging Treatment Regimen for Peritoneal Carcinomatosis

Author(s): Molood Shariati, Wouter Willaert, Wim Ceelen, Stefaan C. De Smedt, Katrien Remaut
Published in: Cancers, Issue 11/7, 2019, Page(s) 906, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11070906

Single Particle Automated Raman Trapping Analysis

Author(s): Jelle Penders, Isaac J. Pence, Conor C. Horgan, Mads S. Bergholt, Christopher S. Wood, Adrian Najer, Ulrike Kauscher, Anika Nagelkerke, Molly M. Stevens
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-06397-6

Scale-Up of the Manufacturing Process To Produce Docetaxel-Loaded mPEG- b -p(HPMA-Bz) Block Copolymer Micelles for Pharmaceutical Applications

Author(s): Jaleesa Bresseleers, Mahsa Bagheri, Gert Storm, Josbert M. Metselaar, Wim E. Hennink, Silvie A. Meeuwissen, Jan C. M. van Hest
Published in: Organic Process Research & Development, Issue 23/12, 2019, Page(s) 2707-2715, ISSN 1083-6160
Publisher: American Chemical Society
DOI: 10.1021/acs.oprd.9b00387

Pulmonary surfactant and drug delivery: Focusing on the role of surfactant proteins

Author(s): Roberta Guagliardo, Jesús Pérez-Gil, Stefaan De Smedt, Koen Raemdonck
Published in: Journal of Controlled Release, Issue 291, 2018, Page(s) 116-126, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2018.10.012

Controlling the morphology of copolymeric vectors for next generation nanomedicine

Author(s): David S. Williams, Imke A.B. Pijpers, Roxane Ridolfo, Jan C.M. van Hest
Published in: Journal of Controlled Release, Issue 259, 2017, Page(s) 29-39, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2017.02.030

High-Throughput Molecular Imaging via Deep-Learning-Enabled Raman Spectroscopy

Author(s): Conor C. Horgan, Magnus Jensen, Anika Nagelkerke, Jean-Philippe St-Pierre, Tom Vercauteren, Molly M. Stevens, Mads S. Bergholt
Published in: Analytical Chemistry, 2021, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.1c02178

Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy

Author(s): Cao, SP, Shao, JX, Wu, HL, Song, S, De Martino, MT, Pijpers, IAB, Friedrich, H, Abdelmohsen, LKEA , Williams, DS2, van Hest, JCM
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22279-w

Integrated photodynamic Raman theranostic system for cancer diagnosis, treatment, and post-treatment molecular monitoring

Author(s): Conor Horgan, Mads Bergholt, Anika Nagelkerke, May Zaw Thin, Isaac Pence, Ulrike Kauscher, Tammy Kalber, Daniel Stuckey, Molly Stevens
Published in: Theranostics, 2021, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.53031

Amphiphilic AIEgen-polymer aggregates: Design, self-assembly and biomedical applications

Author(s): Cao, SP, Shao, JX, Abdelmohsen, LKEA, van Hest, JCM
Published in: Aggregate, 2021, ISSN 2692-4560
Publisher: Wiley & Sons
DOI: 10.1002/agt2.128

Nanoparticles based on natural, engineered or synthetic proteins and polypeptides for drug delivery applications

Author(s): Georgilis, E , Abdelghani, M , Pille, J , Aydinlioglu, E, van Hest, JCM , Lecommandoux, S, Garanger, E
Published in: INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2020.119537

Cucurbit-Like Polymersomes with Aggregation-Induced Emission Properties Show Enzyme-Mediated Motility.

Author(s): Cao, Shoupeng, Wu, Hanglong, Pijpers, Imke A B, Shao, Jingxin, Abdelmohsen, Loai, K E A, Williams, David S, van Hest, Jan C M
Published in: ACS Nano, 2021, ISSN 1936-086X
Publisher: ACS
DOI: 10.1021/acsnano.1c07343

Control over the fibrillization yield by varying the oligomeric nucleation propensities of self-assembling peptides

Author(s): Chun Yin Jerry Lau; Federico Fontana; Laurens D. B. Mandemaker; Dennie Wezendonk; Benjamin Vermeer; Alexandre M. J. J. Bonvin; Renko de Vries; Heyang Zhang; Katrien Remaut; Joep van den Dikkenberg; João Medeiros-Silva; Alia Hassan; Barbara Perrone; Rainer Kuemmerle; Fabrizio Gelain; Wim E. Hennink; Markus Weingarth; Enrico Mastrobattista
Published in: Communications Chemistry, 2020, ISSN 2399-3669
Publisher: Nature Research
DOI: 10.1038/s42004-020-00417-7

Diffusion and Protein Corona Formation of Lipid-Based Nanoparticles in the Vitreous Humor: Profiling and Pharmacokinetic Considerations

Author(s): Shirin Tavakoli, Otto Kalevi Kari, Tiina Turunen, Tatu Lajunen, Mechthild Schmitt, Julia Lehtinen, Fumitaka Tasaka, Petteri Parkkila, Joseph Ndika, Tapani Viitala, Harri Alenius, Arto Urtti, Astrid Subrizi
Published in: MOLECULAR PHARMACEUTICS, 2021, ISSN 1543-8384
Publisher: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.0c00411

Surfactant protein B promotes cytosolic SiRNA delivery by adopting a virus-like mechanism of action

Author(s): Guagliardo, R, Herman, L, Penders, J, Zamborlin, A, De Keersmaecker, H, Van de Vyver, T, Verstraeten, S, Merckx, P, Mingeot-Leclercq, M-P, Echaide, M, Pérez-Gil, J, Stevens, MM, De Smedt, SC, Raemdonck, K
Published in: ACS Nano, 2021, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.0c04489

Exploring the Impact of Morphology on the Properties of Biodegradable Nanoparticles and Their Diffusion in Complex Biological Medium

Author(s): Ridolfo, R, Tavakoli, S, Junnuthula, V, Williams, DS, Urtti, A ,van Hest, JCM
Published in: Biomacromolecules, 2021, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.0c00726

Image-guided Raman spectroscopy probe-tracking for tumor margin delineation

Author(s): Horgan, CC; Bergholt, MS; Thin, MZ; Nagelkerke, A; Kennedy, R; Kalber, TL; Stuckey, DJ; Stevens, MM
Published in: journal of biomedical optics, 2021, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.26.3.036002

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