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Individualised medicine in chronic inflammatory skin diseases

Publications

Addictions in patients with atopic dermatitis: a cross-sectional pilot study in Germany.

Author(s): Pilz AC, Durner V, Schielein MC, Schuster B, Beckmann J, Biedermann T, Eyerich K, Zink A
Published in: J Eur Acad Dermatol Venereol, 2022, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17708

Mechanisms of skin autoimmunity: Cellular and soluble immune components of the skin

Author(s): Johann E. Gudjonsson, Kenji Kabashima, Kilian Eyerich
Published in: Journal of Allergy and Clinical Immunology, 146/1, 2020, Page(s) 8-16, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2020.05.009

CD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis.

Author(s): Thomas J, Wang R, Batra R, Böhner A, Garzorz-Stark N, Eberlein B, Theis F, Biedermann T, Schmidt-Weber C, Zink A, Eyerich K, Eyerich S.
Published in: J Invest Dermatol, 2021, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2020.05.122

Tofacitinib in Hypertrophic Lichen Planus.

Author(s): Seiringer P, Lauffer F, Pilz AC, Boehmer D, Biedermann T, Eyerich K.
Published in: Acta Derm Venereol, 2020, ISSN 0001-5555
Publisher: Taylor & Francis
DOI: 10.2340/00015555-3585

Bisphosphonates for the Treatment of Calcinosis Cutis-A Retrospective Single-Center Study.

Author(s): Rauch L, Hein R, Biedermann T, Eyerich K, Lauffer F
Published in: Biomedicines, 2021, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9111698

New biological treatments for asthma and skin allergies

Author(s): Stefanie Eyerich, Martin Metz, Apostolos Bossios, Kilian Eyerich
Published in: Allergy, 75/3, 2020, Page(s) 546-560, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.14027

Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal

Author(s): Tobias Baumann, Andreas Dunkel, Christian Schmid, Sabine Schmitt, Michael Hiltensperger, Kerstin Lohr, Vibor Laketa, Sainitin Donakonda, Uwe Ahting, Bettina Lorenz-Depiereux, Jan E. Heil, Johann Schredelseker, Luca Simeoni, Caroline Fecher, Nina Körber, Tanja Bauer, Norbert Hüser, Daniel Hartmann, Melanie Laschinger, Kilian Eyerich, Stefanie Eyerich, Martina Anton, Matthew Streeter, Tina Wang, B
Published in: Nature Immunology, 21/5, 2020, Page(s) 555-566, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-020-0666-9

Transferability of suggested molecular classifiers for psoriasis and eczema to the Chinese population.

Author(s): Xu MN, Li L, Pan W, Dai SQ, Wang Q, Wang ML, Zeng K, Huang XW, Eyerich K.
Published in: J Eur Acad Dermatol Venereol, 2021, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.16898

So close, and yet so far away: The dichotomy of the specific immune response and inflammation in psoriasis and atopic dermatitis.

Author(s): A Schäbitz; K Eyerich; K Eyerich; K Eyerich; N Garzorz-Stark; N Garzorz-Stark
Published in: J Intern Med, 1, 2021, ISSN 1365-2796
Publisher: Wiley
DOI: 10.1111/joim.13235

T-Cell‒Mediated Autoimmunity: Mechanisms and Future Directions.

Author(s): Seiringer P, Garzorz-Stark N, Eyerich K.
Published in: J Invest Dermatol, 2021, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2021.04.032

"[Cohort study for long-term follow-up of patients in whom the so-called ""molecular classifier"" is used to distinguish eczema from psoriasis : Background and implementation]."

Author(s): Bentz P, Eyerich K, Weber K, Kluge L, Ofenloch R, Weisshaar E.
Published in: Hautarzt, 2021, ISSN 0017-8470
Publisher: Springer Verlag
DOI: 10.1007/s00105-021-04774-9

Sodium chloride is an ionic checkpoint for human T H 2 cells and shapes the atopic skin microenvironment

Author(s): Julia Matthias, Julia Maul, Rebecca Noster, Hanna Meinl, Ying-Yin Chao, Heiko Gerstenberg, Florian Jeschke, Gilles Gasparoni, Anna Welle, Jörn Walter, Karl Nordström, Klaus Eberhardt, Dennis Renisch, Sainitin Donakonda, Percy Knolle, Dominik Soll, Stephan Grabbe, Natalie Garzorz-Stark, Kilian Eyerich, Tilo Biedermann, Dirk Baumjohann, Christina E. Zielinski
Published in: Science Translational Medicine, 11/480, 2019, Page(s) eaau0683, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aau0683

Toll-Like Receptor 7 Staining in Malignant Epithelial Tumors

Author(s): Regina Franz, Nathalie Ritter, Rüdiger Hein, Tilo Biedermann, Mohammed Al-Sisi, Kilian Eyerich, Natalie Garzorz-Stark, Christian Andres
Published in: The American Journal of Dermatopathology, 39/10, 2017, Page(s) 742-746, ISSN 0193-1091
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/DAD.0000000000000784

STAT1 gain of function and STAT3 loss of function mutations impair IL-17 and IL-22 immunity associated with CMC

Author(s): Julia Hiller, Beate Hagl, Renate Effner, Anne Puel, Martin Schaller, Birgit Mascher, Stefanie Eyerich, Kilian Eyerich, Annette F. Jansson, Johannes Ring, Jean-Laurent Casanova, Ellen D. Renner, Claudia Traidl-Hoffmann
Published in: Journal of Investigative Dermatology, 2017, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.09.035

Sebocytes contribute to skin inflammation by promoting the differentiation of Th17 cells

Author(s): M. Mattii, M. Lovászi, N. Garzorz, A. Atenhan, M. Quaranta, F. Lauffer, A. Konstantinow, M. Küpper, C. C. Zouboulis, L. Kemeny, K. Eyerich, C. B. Schmidt-Weber, D. Törőcsik, S. Eyerich
Published in: British Journal of Dermatology, 2017, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.15879

Sebum lipids influence macrophage polarization and activation

Author(s): M. Lovászi, M. Mattii, K. Eyerich, A. Gácsi, E. Csányi, D. Kovács, R. Rühl, A. Szegedi, L. Kemény, M. Ståhle, C.C. Zouboulis, S. Eyerich, D. Törőcsik
Published in: British Journal of Dermatology, 2017, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.15754

Immune response patterns in non-communicable inflammatory skin diseases

Author(s): Kilian Eyerich, Stefanie Eyerich
Published in: Journal of the European Academy of Dermatology and Venereology, 2017, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.14673

A novel molecular disease classifier for psoriasis and eczema

Author(s): Natalie Garzorz-Stark, Linda Krause, Felix Lauffer, Anne Atenhan, Jenny Thomas, Sebastian P. Stark, Regina Franz, Stephan Weidinger, Anna Balato, Nikola S. Mueller, Fabian J. Theis, Johannes Ring, Carsten B. Schmidt-Weber, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich
Published in: Experimental Dermatology, 25/10, 2016, Page(s) 767-774, ISSN 0906-6705
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/exd.13077

Newly acquired kiwi fruit allergy after bone marrow transplantation from a kiwi-allergic donor

Author(s): N. Garzorz, J. Thomas, B. Eberlein, C. Haferlach, J. Ring, T. Biedermann, C. Schmidt-Weber, K. Eyerich, F. Seifert, S. Eyerich
Published in: Journal of the European Academy of Dermatology and Venereology, 30/7, 2016, Page(s) 1136-1139, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.13617

Addiction: an underestimated problem in psoriasis health care

Author(s): A. Zink, M. Herrmann, T. Fischer, F. Lauffer, N. Garzorz-Stark, A. Böhner, C.D. Spinner, T. Biedermann, K. Eyerich
Published in: Journal of the European Academy of Dermatology and Venereology, 31/8, 2017, Page(s) 1308-1315, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.14204

Motion correction in optoacoustic mesoscopy

Author(s): Mathias Schwarz, Natalie Garzorz-Stark, Kilian Eyerich, Juan Aguirre, Vasilis Ntziachristos
Published in: Scientific Reports, 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-11277-y

The Multi-Modal Immune Pathogenesis of Atopic Eczema

Author(s): Kilian Eyerich, Stefanie Eyerich, Tilo Biedermann
Published in: Trends in Immunology, 36/12, 2015, Page(s) 788-801, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2015.10.006

Interleukin-22 Promotes Wound Repair in Diabetes by Improving Keratinocyte Pro-Healing Functions

Author(s): Simona Avitabile, Teresa Odorisio, Stefania Madonna, Stefanie Eyerich, Liliana Guerra, Kilian Eyerich, Giovanna Zambruno, Andrea Cavani, Francesca Cianfarani
Published in: Journal of Investigative Dermatology, 135/11, 2015, Page(s) 2862-2870, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1038/jid.2015.278

Dissecting susceptibility from exogenous triggers: the model of alopecia areata and associated inflammatory skin diseases

Author(s): N. Garzorz, M. Alsisi, A. Todorova, A. Atenhan, J. Thomas, F. Lauffer, J. Ring, C. Schmidt-Weber, T. Biedermann, S. Eyerich, K. Eyerich
Published in: Journal of the European Academy of Dermatology and Venereology, 29/12, 2015, Page(s) 2429-2435, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.13325

Acute Generalized Pustular Psoriasis Treated With the IL-17A Antibody Secukinumab

Author(s): Alexander Böhner, Sophie Roenneberg, Kilian Eyerich, Bernadette Eberlein, Tilo Biedermann
Published in: JAMA Dermatology, 152/4, 2016, Page(s) 482, ISSN 2168-6068
Publisher: American Medical Association
DOI: 10.1001/jamadermatol.2015.4686

Use of systemic corticosteroids for atopic dermatitis: International Eczema Council consensus statement

Author(s): A.M. Drucker, K. Eyerich, M.S. de Bruin-Weller, J.P. Thyssen, P.I. Spuls, A.D. Irvine, G. Girolomoni, S. Dhar, C. Flohr, D.F. Murrell, A.S. Paller, E. Guttman-Yassky
Published in: British Journal of Dermatology, 2017, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.15928

Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate T H 17-deviated acute contact dermatitis in human subjects

Author(s): Natalie Garzorz-Stark, Felix Lauffer, Linda Krause, Jenny Thomas, Anne Atenhan, Regina Franz, Sophie Roenneberg, Alexander Boehner, Manja Jargosch, Richa Batra, Nikola S. Mueller, Stefan Haak, Christina Groß, Olaf Groß, Claudia Traidl-Hoffmann, Fabian J. Theis, Carsten B. Schmidt-Weber, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich
Published in: Journal of Allergy and Clinical Immunology, 2017, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2017.07.045

IL-17 and IL-22 in immunity: Driving protection and pathology

Author(s): Kilian Eyerich, Valentina Dimartino, Andrea Cavani
Published in: European Journal of Immunology, 47/4, 2017, Page(s) 607-614, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201646723

Assessing nailfold microvascular structure with ultra-wideband raster-scan optoacoustic mesoscopy

Author(s): J. Aguirre, B. Hindelang, Andrei Berezhnoi, U. Darsow, F. Lauffer, K. Eyerich, T. Biedermann, V. Ntziachristos
Published in: Photoacoustics, 10, 2018, Page(s) 31-37, ISSN 2213-5979
Publisher: Elsevier GmbH
DOI: 10.1016/j.pacs.2018.02.002

Cutaneous Barriers and Skin Immunity: Differentiating A Connected Network

Author(s): Stefanie Eyerich, Kilian Eyerich, Claudia Traidl-Hoffmann, Tilo Biedermann
Published in: Trends in Immunology, 39/4, 2018, Page(s) 315-327, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2018.02.004

Ixekizumab for acrodermatitis continua

Author(s): Anna Caroline Pilz, Sophie Roenneberg, Tilo Biedermann, Kilian Eyerich
Published in: JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 16/7, 2018, Page(s) 907-910, ISSN 1610-0379
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ddg.13568

Human exposure to airborne pollen and relationships with symptoms and immune responses: Indoors versus outdoors, circadian patterns and meteorological effects in alpine and urban environments

Author(s): Athanasios Damialis, Franziska Häring, Mehmet Gökkaya, Denise Rauer, Matthias Reiger, Sebastian Bezold, Nikolaos Bounas-Pyrros, Kilian Eyerich, Antonia Todorova, Gertrud Hammel, Stefanie Gilles, Claudia Traidl-Hoffmann
Published in: Science of The Total Environment, 653, 2019, Page(s) 190-199, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2018.10.366

Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council

Author(s): Kilian Eyerich, Sara J. Brown, Bethany E. Perez White, Reiko J. Tanaka, Robert Bissonette, Sandipan Dhar, Thomas Bieber, Dirk J. Hijnen, Emma Guttman-Yassky, Alan Irvine, Jacob P. Thyssen, Christian Vestergaard, Thomas Werfel, Andreas Wollenberg, Amy S. Paller, Nick J. Reynolds
Published in: Journal of Allergy and Clinical Immunology, 143/1, 2019, Page(s) 36-45, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2018.10.033

Non-invasive imaging in dermatology and the unique potential of Raster-Scan Optoacoustic Mesoscopy (RSOM)

Author(s): B. Hindelang, J. Aguirre, M. Schwarz, A. Berezhnoi, K. Eyerich, V. Ntziachristos, T. Biedermann, U. Darsow
Published in: Journal of the European Academy of Dermatology and Venereology, 2018, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.15342

Type I Immune Response Induces Keratinocyte Necroptosis and Is Associated with Interface Dermatitis

Author(s): Felix Lauffer, Manja Jargosch, Linda Krause, Natalie Garzorz-Stark, Regina Franz, Sophie Roenneberg, Alexander Böhner, Nikola S. Mueller, Fabian J. Theis, Carsten B. Schmidt-Weber, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich
Published in: Journal of Investigative Dermatology, 138/8, 2018, Page(s) 1785-1794, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2018.02.034

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

Author(s): Thomas Werfel, Jean-Pierre Allam, Tilo Biedermann, Kilian Eyerich, Stefanie Gilles, Emma Guttman-Yassky, Wolfram Hoetzenecker, Edward Knol, Hans-Uwe Simon, Andreas Wollenberg, Thomas Bieber, Roger Lauener, Peter Schmid-Grendelmeier, Claudia Traidl-Hoffmann, Cezmi A. Akdis
Published in: Journal of Allergy and Clinical Immunology, 138/2, 2016, Page(s) 336-349, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2016.06.010

Relations between epidermal barrier dysregulation and Staphylococcus species–dominated microbiome dysbiosis in patients with atopic dermatitis

Author(s): Can Altunbulakli, Matthias Reiger, Avidan U. Neumann, Natalie Garzorz-Stark, Megan Fleming, Claudia Huelpuesch, Francesc Castro-Giner, Kilian Eyerich, Cezmi A. Akdis, Claudia Traidl-Hoffmann
Published in: Journal of Allergy and Clinical Immunology, 142/5, 2018, Page(s) 1643-1647.e12, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2018.07.005

Is the humoral immunity dispensable for the pathogenesis of psoriasis?

Author(s): J. Thomas, M. Küpper, R. Batra, M. Jargosch, A. Atenhan, V. Baghin, L. Krause, F. Lauffer, T. Biedermann, F.J. Theis, K. Eyerich, S. Eyerich, N. Garzorz-Stark
Published in: Journal of the European Academy of Dermatology and Venereology, 2018, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.15101

Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis

Author(s): Nick Vandeghinste, Jürgen Klattig, Catherine Jagerschmidt, Stéphanie Lavazais, Florence Marsais, Jan D. Haas, Marielle Auberval, Felix Lauffer, Tara Moran, Mate Ongenaert, Maarten Van Balen, Sonia Dupont, Liên Lepescheux, Teresa Garcia, Stefan Härtle, Kilian Eyerich, Padraic G. Fallon, Reginald Brys, Stefan Steidl
Published in: Journal of Investigative Dermatology, 138/7, 2018, Page(s) 1555-1563, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2018.01.036

Generalized pustular psoriasis - a model disease for specific targeted immunotherapy, systematic review

Author(s): Alexander Boehner, Alexander A. Navarini, Kilian Eyerich
Published in: Experimental Dermatology, 27/10, 2018, Page(s) 1067-1077, ISSN 0906-6705
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/exd.13699

De novo pathway-based biomarker identification

Author(s): Nicolas Alcaraz, Markus List, Richa Batra, Fabio Vandin, Henrik J. Ditzel, Jan Baumbach
Published in: Nucleic Acids Research, 45/16, 2017, Page(s) e151-e151, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkx642

Predicting persistence of atopic dermatitis in children using clinical attributes and serum proteins

Author(s): Felix Lauffer, Veronika Baghin, Marie Standl, Sebastian P. Stark, Manja Jargosch, Julius Wehrle, Jenny Thomas, Carsten B. Schmidt‐Weber, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich, Natalie Garzorz‐Stark
Published in: Allergy, 2020, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.14557

IL‐17C amplifies epithelial inflammation in human psoriasis and atopic eczema

Author(s): F. Lauffer, M. Jargosch, V. Baghin, L. Krause, W. Kempf, M. Absmaier‐Kijak, M. Morelli, S. Madonna, F. Marsais, L. Lepescheux, C. Albanesi, N.S. Müller, F.J. Theis, C. Schmidt‐Weber, S. Eyerich, T. Biedermann, N. Vandeghinste, S. Steidl, K. Eyerich
Published in: Journal of the European Academy of Dermatology and Venereology, 34/4, 2020, Page(s) 800-809, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.16126

Keratinocytes Regulate the Threshold of Inflammation by Inhibiting T Cell Effector Functions.

Author(s): Seiringer P, Eyerich S, Eyerich K, Dittlein D, Pilz AC, Scala E, Ring J, Behrendt H, Cavani A, Traidl-Hoffmann C.
Published in: Cells, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10071606