Individualised medicine in chronic inflammatory skin diseases

Project Information

IMCIS

Grant agreement ID: 676858

DOI 10.3030/676858

Project closed

EC signature date 7 June 2016

Start date 1 July 2016

End date 31 October 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 495 906,00

EU contribution € 1 495 906,00

Coordinated by

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (29)

Addictions in patients with atopic dermatitis: a cross-sectional pilot study in Germany.

Author(s): Pilz AC, Durner V, Schielein MC, Schuster B, Beckmann J, Biedermann T, Eyerich K, Zink A
Published in: J Eur Acad Dermatol Venereol, 2022, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17708

Mechanisms of skin autoimmunity: Cellular and soluble immune components of the skin

Author(s): Johann E. Gudjonsson, Kenji Kabashima, Kilian Eyerich
Published in: Journal of Allergy and Clinical Immunology, Issue 146/1, 2020, Page(s) 8-16, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2020.05.009

CD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis.

Author(s): Thomas J, Wang R, Batra R, Böhner A, Garzorz-Stark N, Eberlein B, Theis F, Biedermann T, Schmidt-Weber C, Zink A, Eyerich K, Eyerich S.
Published in: J Invest Dermatol, 2021, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2020.05.122

Tofacitinib in Hypertrophic Lichen Planus.

Author(s): Seiringer P, Lauffer F, Pilz AC, Boehmer D, Biedermann T, Eyerich K.
Published in: Acta Derm Venereol, 2020, ISSN 0001-5555
Publisher: Taylor & Francis
DOI: 10.2340/00015555-3585

Bisphosphonates for the Treatment of Calcinosis Cutis-A Retrospective Single-Center Study.

Author(s): Rauch L, Hein R, Biedermann T, Eyerich K, Lauffer F
Published in: Biomedicines, 2021, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9111698

New biological treatments for asthma and skin allergies

Author(s): Stefanie Eyerich, Martin Metz, Apostolos Bossios, Kilian Eyerich
Published in: Allergy, Issue 75/3, 2020, Page(s) 546-560, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.14027

So close, and yet so far away: The dichotomy of the specific immune response and inflammation in psoriasis and atopic dermatitis.

Author(s): A Schäbitz; K Eyerich; K Eyerich; K Eyerich; N Garzorz-Stark; N Garzorz-Stark
Published in: J Intern Med, Issue 1, 2021, ISSN 1365-2796
Publisher: Wiley
DOI: 10.1111/joim.13235

STAT1 gain of function and STAT3 loss of function mutations impair IL-17 and IL-22 immunity associated with CMC

Author(s): Julia Hiller, Beate Hagl, Renate Effner, Anne Puel, Martin Schaller, Birgit Mascher, Stefanie Eyerich, Kilian Eyerich, Annette F. Jansson, Johannes Ring, Jean-Laurent Casanova, Ellen D. Renner, Claudia Traidl-Hoffmann
Published in: Journal of Investigative Dermatology, 2017, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.09.035

Sebocytes contribute to skin inflammation by promoting the differentiation of Th17 cells

Author(s): M. Mattii, M. Lovászi, N. Garzorz, A. Atenhan, M. Quaranta, F. Lauffer, A. Konstantinow, M. Küpper, C. C. Zouboulis, L. Kemeny, K. Eyerich, C. B. Schmidt-Weber, D. Törőcsik, S. Eyerich
Published in: British Journal of Dermatology, 2017, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.15879

Sebum lipids influence macrophage polarization and activation

Author(s): M. Lovászi, M. Mattii, K. Eyerich, A. Gácsi, E. Csányi, D. Kovács, R. Rühl, A. Szegedi, L. Kemény, M. Ståhle, C.C. Zouboulis, S. Eyerich, D. Törőcsik
Published in: British Journal of Dermatology, 2017, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.15754

Immune response patterns in non-communicable inflammatory skin diseases

Author(s): Kilian Eyerich, Stefanie Eyerich
Published in: Journal of the European Academy of Dermatology and Venereology, 2017, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.14673

Newly acquired kiwi fruit allergy after bone marrow transplantation from a kiwi-allergic donor

Author(s): N. Garzorz, J. Thomas, B. Eberlein, C. Haferlach, J. Ring, T. Biedermann, C. Schmidt-Weber, K. Eyerich, F. Seifert, S. Eyerich
Published in: Journal of the European Academy of Dermatology and Venereology, Issue 30/7, 2016, Page(s) 1136-1139, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.13617

Motion correction in optoacoustic mesoscopy

Author(s): Mathias Schwarz, Natalie Garzorz-Stark, Kilian Eyerich, Juan Aguirre, Vasilis Ntziachristos
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-11277-y

Interleukin-22 Promotes Wound Repair in Diabetes by Improving Keratinocyte Pro-Healing Functions

Author(s): Simona Avitabile, Teresa Odorisio, Stefania Madonna, Stefanie Eyerich, Liliana Guerra, Kilian Eyerich, Giovanna Zambruno, Andrea Cavani, Francesca Cianfarani
Published in: Journal of Investigative Dermatology, Issue 135/11, 2015, Page(s) 2862-2870, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1038/jid.2015.278

Use of systemic corticosteroids for atopic dermatitis: International Eczema Council consensus statement

Author(s): A.M. Drucker, K. Eyerich, M.S. de Bruin-Weller, J.P. Thyssen, P.I. Spuls, A.D. Irvine, G. Girolomoni, S. Dhar, C. Flohr, D.F. Murrell, A.S. Paller, E. Guttman-Yassky
Published in: British Journal of Dermatology, 2017, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.15928

Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate T H 17-deviated acute contact dermatitis in human subjects

Author(s): Natalie Garzorz-Stark, Felix Lauffer, Linda Krause, Jenny Thomas, Anne Atenhan, Regina Franz, Sophie Roenneberg, Alexander Boehner, Manja Jargosch, Richa Batra, Nikola S. Mueller, Stefan Haak, Christina Groß, Olaf Groß, Claudia Traidl-Hoffmann, Fabian J. Theis, Carsten B. Schmidt-Weber, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich
Published in: Journal of Allergy and Clinical Immunology, 2017, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2017.07.045

IL-17 and IL-22 in immunity: Driving protection and pathology

Author(s): Kilian Eyerich, Valentina Dimartino, Andrea Cavani
Published in: European Journal of Immunology, Issue 47/4, 2017, Page(s) 607-614, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201646723

Assessing nailfold microvascular structure with ultra-wideband raster-scan optoacoustic mesoscopy

Author(s): J. Aguirre, B. Hindelang, Andrei Berezhnoi, U. Darsow, F. Lauffer, K. Eyerich, T. Biedermann, V. Ntziachristos
Published in: Photoacoustics, Issue 10, 2018, Page(s) 31-37, ISSN 2213-5979
Publisher: Elsevier GmbH
DOI: 10.1016/j.pacs.2018.02.002

Ixekizumab for acrodermatitis continua

Author(s): Anna Caroline Pilz, Sophie Roenneberg, Tilo Biedermann, Kilian Eyerich
Published in: JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Issue 16/7, 2018, Page(s) 907-910, ISSN 1610-0379
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ddg.13568

Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council

Author(s): Kilian Eyerich, Sara J. Brown, Bethany E. Perez White, Reiko J. Tanaka, Robert Bissonette, Sandipan Dhar, Thomas Bieber, Dirk J. Hijnen, Emma Guttman-Yassky, Alan Irvine, Jacob P. Thyssen, Christian Vestergaard, Thomas Werfel, Andreas Wollenberg, Amy S. Paller, Nick J. Reynolds
Published in: Journal of Allergy and Clinical Immunology, Issue 143/1, 2019, Page(s) 36-45, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2018.10.033

Non-invasive imaging in dermatology and the unique potential of Raster-Scan Optoacoustic Mesoscopy (RSOM)

Author(s): B. Hindelang, J. Aguirre, M. Schwarz, A. Berezhnoi, K. Eyerich, V. Ntziachristos, T. Biedermann, U. Darsow
Published in: Journal of the European Academy of Dermatology and Venereology, 2018, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.15342

Type I Immune Response Induces Keratinocyte Necroptosis and Is Associated with Interface Dermatitis

Author(s): Felix Lauffer, Manja Jargosch, Linda Krause, Natalie Garzorz-Stark, Regina Franz, Sophie Roenneberg, Alexander Böhner, Nikola S. Mueller, Fabian J. Theis, Carsten B. Schmidt-Weber, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich
Published in: Journal of Investigative Dermatology, Issue 138/8, 2018, Page(s) 1785-1794, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2018.02.034

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

Author(s): Thomas Werfel, Jean-Pierre Allam, Tilo Biedermann, Kilian Eyerich, Stefanie Gilles, Emma Guttman-Yassky, Wolfram Hoetzenecker, Edward Knol, Hans-Uwe Simon, Andreas Wollenberg, Thomas Bieber, Roger Lauener, Peter Schmid-Grendelmeier, Claudia Traidl-Hoffmann, Cezmi A. Akdis
Published in: Journal of Allergy and Clinical Immunology, Issue 138/2, 2016, Page(s) 336-349, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2016.06.010

Relations between epidermal barrier dysregulation and Staphylococcus species–dominated microbiome dysbiosis in patients with atopic dermatitis

Author(s): Can Altunbulakli, Matthias Reiger, Avidan U. Neumann, Natalie Garzorz-Stark, Megan Fleming, Claudia Huelpuesch, Francesc Castro-Giner, Kilian Eyerich, Cezmi A. Akdis, Claudia Traidl-Hoffmann
Published in: Journal of Allergy and Clinical Immunology, Issue 142/5, 2018, Page(s) 1643-1647.e12, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2018.07.005

Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis

Author(s): Nick Vandeghinste, Jürgen Klattig, Catherine Jagerschmidt, Stéphanie Lavazais, Florence Marsais, Jan D. Haas, Marielle Auberval, Felix Lauffer, Tara Moran, Mate Ongenaert, Maarten Van Balen, Sonia Dupont, Liên Lepescheux, Teresa Garcia, Stefan Härtle, Kilian Eyerich, Padraic G. Fallon, Reginald Brys, Stefan Steidl
Published in: Journal of Investigative Dermatology, Issue 138/7, 2018, Page(s) 1555-1563, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2018.01.036

Generalized pustular psoriasis - a model disease for specific targeted immunotherapy, systematic review

Author(s): Alexander Boehner, Alexander A. Navarini, Kilian Eyerich
Published in: Experimental Dermatology, Issue 27/10, 2018, Page(s) 1067-1077, ISSN 0906-6705
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/exd.13699

De novo pathway-based biomarker identification

Author(s): Nicolas Alcaraz, Markus List, Richa Batra, Fabio Vandin, Henrik J. Ditzel, Jan Baumbach
Published in: Nucleic Acids Research, Issue 45/16, 2017, Page(s) e151-e151, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkx642

Predicting persistence of atopic dermatitis in children using clinical attributes and serum proteins

Author(s): Felix Lauffer, Veronika Baghin, Marie Standl, Sebastian P. Stark, Manja Jargosch, Julius Wehrle, Jenny Thomas, Carsten B. Schmidt‐Weber, Tilo Biedermann, Stefanie Eyerich, Kilian Eyerich, Natalie Garzorz‐Stark
Published in: Allergy, 2020, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.14557

Keratinocytes Regulate the Threshold of Inflammation by Inhibiting T Cell Effector Functions.

Author(s): Seiringer P, Eyerich S, Eyerich K, Dittlein D, Pilz AC, Scala E, Ring J, Behrendt H, Cavani A, Traidl-Hoffmann C.
Published in: Cells, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10071606