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Next-generation Detection of Antigen Responsive T-cells

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers (opens in new window)

Author(s): Sunil Kumar Saini, Andreas Due Ørskov, Anne-Mette Bjerregaard, Ashwin Unnikrishnan, Staffan Holmberg-Thydén, Annie Borch, Kathrine Valentini Jensen, Govardhan Anande, Amalie Kai Bentzen, Andrea Marion Marquard, Tripti Tamhane, Marianne Bach Treppendahl, Anne Ortved Gang, Inge Høgh Dufva, Zoltan Szallasi, Nicola Ternette, Anders Gorm Pedersen, Aron Charles Eklund, John Pimanda, Kirsten Grønbæk
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-19464-8

The T cell differentiation landscape is shaped by tumour mutations in lung cancer (opens in new window)

Author(s): Ehsan Ghorani, James L. Reading, Jake Y. Henry, Marc Robert de Massy, Rachel Rosenthal, Virginia Turati, Kroopa Joshi, Andrew J. S. Furness, Assma Ben Aissa, Sunil Kumar Saini, Sofie Ramskov, Andrew Georgiou, Mariana Werner Sunderland, Yien Ning Sophia Wong, Maria Vila De Mucha, William Day, Felipe Galvez-Cancino, Pablo D. Becker, Imran Uddin, Theres Oakes, Mazlina Ismail, Tahel Ronel, Annemarie W
Published in: Nature Cancer, Issue 1/5, 2020, Page(s) 546-561, ISSN 2662-1347
Publisher: Nature publishing group
DOI: 10.1038/s43018-020-0066-y

Human endogenous retroviruses and their implication for immunotherapeutics of cancer (opens in new window)

Author(s): A S Attermann, A -M Bjerregaard, S K Saini, K Grønbæk, S R Hadrup
Published in: Annals of Oncology, Issue 29/11, 2018, Page(s) 2183-2191, ISSN 0923-7534
Publisher: Oxford University Press
DOI: 10.1093/annonc/mdy413

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide–MHC complexes (opens in new window)

Author(s): Amalie K Bentzen, Lina Such, Kamilla K Jensen, Andrea M Marquard, Leon E Jessen, Natalie J Miller, Candice D Church, Rikke Lyngaa, David M Koelle, Jürgen C Becker, Carsten Linnemann, Ton N M Schumacher, Paolo Marcatili, Paul Nghiem, Morten Nielsen, Sine R Hadrup
Published in: Nature Biotechnology, Issue 36/12, 2018, Page(s) 1191-1196, ISSN 1087-0156
Publisher: Nature Publishing Group
DOI: 10.1038/nbt.4303

Determining T-cell specificity to understand and treat disease (opens in new window)

Author(s): Sine Reker Hadrup, Evan W. Newell
Published in: Nature Biomedical Engineering, Issue 1/10, 2017, Page(s) 784-795, ISSN 2157-846X
Publisher: Nature Publishing group
DOI: 10.1038/s41551-017-0143-4

T-cell-receptor cross-recognition and strategies to select safe T-cell receptors for clinical translation (opens in new window)

Author(s): Amalie Kai Bentzen, Sine Reker Hadrup
Published in: Immuno-Oncology Technology, Issue 2, 2019, Page(s) 1-10, ISSN 2590-0188
Publisher: Elsevier Inc
DOI: 10.1016/j.iotech.2019.06.003

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells (opens in new window)

Author(s): Sunil Kumar Saini, Tripti Tamhane, Raghavendra Anjanappa, Ankur Saikia, Sofie Ramskov, Marco Donia, Inge Marie Svane, Søren Nyboe Jakobsen, Maria Garcia-Alai, Martin Zacharias, Rob Meijers, Sebastian Springer, Sine Reker Hadrup
Published in: Science Immunology, Issue 4/37, 2019, Page(s) eaau9039, ISSN 2470-9468
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.aau9039

Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations (opens in new window)

Author(s): Ulla Kring Hansen, Sofie Ramskov, Anne-Mette Bjerregaard, Annie Borch, Rikke Andersen, Arianna Draghi, Marco Donia, Amalie Kai Bentzen, Andrea Marion Marquard, Zoltan Szallasi, Aron Charles Eklund, Inge Marie Svane, Sine Reker Hadrup
Published in: Frontiers in Immunology, Issue 11, 2020, ISSN 1664-3224
Publisher: Frontiers Immunology
DOI: 10.3389/fimmu.2020.00373

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