Next-generation Detection of Antigen Responsive T-cells

Pubblicazioni

Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

Autori: Sunil Kumar Saini, Andreas Due Ørskov, Anne-Mette Bjerregaard, Ashwin Unnikrishnan, Staffan Holmberg-Thydén, Annie Borch, Kathrine Valentini Jensen, Govardhan Anande, Amalie Kai Bentzen, Andrea Marion Marquard, Tripti Tamhane, Marianne Bach Treppendahl, Anne Ortved Gang, Inge Høgh Dufva, Zoltan Szallasi, Nicola Ternette, Anders Gorm Pedersen, Aron Charles Eklund, John Pimanda, Kirsten Grønbæk
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-19464-8

The T cell differentiation landscape is shaped by tumour mutations in lung cancer

Autori: Ehsan Ghorani, James L. Reading, Jake Y. Henry, Marc Robert de Massy, Rachel Rosenthal, Virginia Turati, Kroopa Joshi, Andrew J. S. Furness, Assma Ben Aissa, Sunil Kumar Saini, Sofie Ramskov, Andrew Georgiou, Mariana Werner Sunderland, Yien Ning Sophia Wong, Maria Vila De Mucha, William Day, Felipe Galvez-Cancino, Pablo D. Becker, Imran Uddin, Theres Oakes, Mazlina Ismail, Tahel Ronel, Annemarie W
Pubblicato in: Nature Cancer, Numero 1/5, 2020, Pagina/e 546-561, ISSN 2662-1347
Editore: Nature publishing group
DOI: 10.1038/s43018-020-0066-y

Human endogenous retroviruses and their implication for immunotherapeutics of cancer

Autori: A S Attermann, A -M Bjerregaard, S K Saini, K Grønbæk, S R Hadrup
Pubblicato in: Annals of Oncology, Numero 29/11, 2018, Pagina/e 2183-2191, ISSN 0923-7534
Editore: Oxford University Press
DOI: 10.1093/annonc/mdy413

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide–MHC complexes

Autori: Amalie K Bentzen, Lina Such, Kamilla K Jensen, Andrea M Marquard, Leon E Jessen, Natalie J Miller, Candice D Church, Rikke Lyngaa, David M Koelle, Jürgen C Becker, Carsten Linnemann, Ton N M Schumacher, Paolo Marcatili, Paul Nghiem, Morten Nielsen, Sine R Hadrup
Pubblicato in: Nature Biotechnology, Numero 36/12, 2018, Pagina/e 1191-1196, ISSN 1087-0156
Editore: Nature Publishing Group
DOI: 10.1038/nbt.4303

Determining T-cell specificity to understand and treat disease

Autori: Sine Reker Hadrup, Evan W. Newell
Pubblicato in: Nature Biomedical Engineering, Numero 1/10, 2017, Pagina/e 784-795, ISSN 2157-846X
Editore: Nature Publishing group
DOI: 10.1038/s41551-017-0143-4

T-cell-receptor cross-recognition and strategies to select safe T-cell receptors for clinical translation

Autori: Amalie Kai Bentzen, Sine Reker Hadrup
Pubblicato in: Immuno-Oncology Technology, Numero 2, 2019, Pagina/e 1-10, ISSN 2590-0188
Editore: Elsevier Inc
DOI: 10.1016/j.iotech.2019.06.003

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

Autori: Sunil Kumar Saini, Tripti Tamhane, Raghavendra Anjanappa, Ankur Saikia, Sofie Ramskov, Marco Donia, Inge Marie Svane, Søren Nyboe Jakobsen, Maria Garcia-Alai, Martin Zacharias, Rob Meijers, Sebastian Springer, Sine Reker Hadrup
Pubblicato in: Science Immunology, Numero 4/37, 2019, Pagina/e eaau9039, ISSN 2470-9468
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.aau9039

Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations

Autori: Ulla Kring Hansen, Sofie Ramskov, Anne-Mette Bjerregaard, Annie Borch, Rikke Andersen, Arianna Draghi, Marco Donia, Amalie Kai Bentzen, Andrea Marion Marquard, Zoltan Szallasi, Aron Charles Eklund, Inge Marie Svane, Sine Reker Hadrup
Pubblicato in: Frontiers in Immunology, Numero 11, 2020, ISSN 1664-3224
Editore: Frontiers Immunology
DOI: 10.3389/fimmu.2020.00373

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