Catalytic C–F Bond Functionalization for the Fixation of Environmentally Persistent Fluorocarbons

Project Information

FluoroFix

Grant agreement ID: 677367

DOI

10.3030/677367

Project closed

EC signature date 22 January 2016

Start date 1 April 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 496 925,00

EU contribution

€ 1 496 925,00

Coordinated by

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (32)

Catalyst control of selectivity in the C–O bond alumination of biomass derived furans

Author(s): Thomas N. Hooper, Ryan K. Brown, Feriel Rekhroukh, Martí Garçon, Andrew J. P. White, Paulo J. Costa, Mark R. Crimmin
Published in: Chemical Science, Issue 11/30, 2020, Page(s) 7850-7857, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc01918f

Reactions of an Aluminum(I) Reagent with 1,2-, 1,3-, and 1,5-Dienes: Dearomatization, Reversibility, and a Pericyclic Mechanism

Author(s): Clare Bakewell, Martí Garçon, Richard Y. Kong, Louisa O’Hare, Andrew J. P. White, Mark R. Crimmin
Published in: Inorganic Chemistry, Issue 59/7, 2020, Page(s) 4608-4616, ISSN 0020-1669
Publisher: American Chemical Society
DOI: 10.1021/acs.inorgchem.9b03701

Palladium‐Catalysed C−H Bond Zincation of Arenes: Scope, Mechanism, and the Role of Heterometallic Intermediates

Author(s): Martí Garçon; Nicolette Wee Mun; Andrew J. P. White; Mark R. Crimmin
Published in: Angewandte Chemie International Edition, Issue 3, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202014960

Alumination of aryl methyl ethers: switching between sp 2 and sp 3 C–O bond functionalisation with Pd-catalysis

Author(s): Ryan K. Brown; Thomas N. Hooper; Feriel Rekhroukh; Andrew J. P. White; Paulo J. Costa; Mark R. Crimmin
Published in: Chemical Communications, Issue 2, 2021, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cc05408b

Complete Deconstruction of SF6 by an Aluminium(I) Compound

Author(s): Daniel Sheldon; Mark Crimmin
Published in: Chemical Communications (Cambridge, England), Issue 1, 2021, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cc02838c

Organocatalyzed Fluoride Metathesis

Author(s): Daniel Mulryan, Andrew J. P. White, Mark R. Crimmin
Published in: Organic Letters, Issue 22/23, 2020, Page(s) 9351-9355, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.0c03593

Defluorosilylation of Trifluoromethane: Upgrading anEnvironmentally Damaging Fluorocarbon

Author(s): Daniel J. Sheldon, Greg Coates, Mark R. Crimmin
Published in: Chemical Communications, Issue 10.1039/d0cc04592f, 2020, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0cc04592f

Catalytic C–H to C–M (M = Al, Mg) bond transformations with heterometallic complexes

Author(s): Maria Batuecas, Nikolaus Gorgas, Mark R. Crimmin
Published in: Chemical Science, 2020, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc03695a

Palladium-Catalyzed Carbon-Fluorine and Carbon-Hydrogen Bond Alumination of Fluoroarenes and Heteroarenes

Author(s): Wenyi Chen, Thomas N. Hooper, Jamues Ng, Andrew J. P. White, Mark R. Crimmin
Published in: Angewandte Chemie International Edition, Issue 56/41, 2017, Page(s) 12687-12691, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201706378

Mild sp 2 Carbon–Oxygen Bond Activation by an Isolable Ruthenium(II) Bis(dinitrogen) Complex: Experiment and Theory

Author(s): Samantha Lau, Bryan Ward, Xueer Zhou, Andrew J. P. White, Ian J. Casely, Stuart A. Macgregor, Mark R. Crimmin
Published in: Organometallics, Issue 36/18, 2017, Page(s) 3654-3663, ISSN 0276-7333
Publisher: American Chemical Society
DOI: 10.1021/acs.organomet.7b00632

A combined experimental and computational study on the reaction of fluoroarenes with Mg–Mg, Mg–Zn, Mg–Al and Al–Zn bonds

Author(s): Clare Bakewell, Bryan J. Ward, Andrew J. P. White, Mark R. Crimmin
Published in: Chemical Science, Issue 9/8, 2018, Page(s) 2348-2356, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c7sc05059c

Room temperature catalytic carbon–hydrogen bond alumination of unactivated arenes: mechanism and selectivity

Author(s): Thomas N. Hooper, Martí Garçon, Andrew J. P. White, Mark R. Crimmin
Published in: Chemical Science, Issue 9/24, 2018, Page(s) 5435-5440, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8sc02072h

Reactions of Fluoroalkanes with Mg−Mg Bonds: Scope, sp 3 C−F/sp 2 C−F Coupling and Mechanism

Author(s): Greg Coates, Bryan J. Ward, Clare Bakewell, Andrew J. P. White, Mark R. Crimmin
Published in: Chemistry - A European Journal, Issue 24/61, 2018, Page(s) 16282-16286, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201804580

Reactions of Fluoroalkenes with an Aluminium(I) Complex

Author(s): Clare Bakewell, Andrew J. P. White, Mark R. Crimmin
Published in: Angewandte Chemie International Edition, Issue 57/22, 2018, Page(s) 6638-6642, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201802321

Palladium-catalysed magnesiation of benzene

Author(s): Martí Garçon, Andrew J. P. White, Mark R. Crimmin
Published in: Chemical Communications, Issue 54/87, 2018, Page(s) 12326-12328, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/C8CC06392C

Carbon Chain Growth by Sequential Reactions of CO and CO 2 with [W(CO) 6 ] and an Aluminum(I) Reductant

Author(s): Richard Y. Kong, Mark R. Crimmin
Published in: Journal of the American Chemical Society, Issue 140/42, 2018, Page(s) 13614-13617, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.8b09761

Reversible insertion of CO into an aluminium–carbon bond

Author(s): Richard Y. Kong, Mark R. Crimmin
Published in: Chemical Communications, 2019, Page(s) 10.1039/c9cc02818h, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9cc02818h

Reversible alkene binding and allylic C–H activation with an aluminium( i ) complex

Author(s): Clare Bakewell, Andrew J. P. White, Mark R. Crimmin
Published in: Chemical Science, Issue 10/8, 2019, Page(s) 2452-2458, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8sc04865g

Selective Hydrodefluorination of Hexafluoropropene to Industrially Relevant Hydrofluoroolefins

Author(s): Nicholas Phillips, Andrew White, Mark Crimmin
Published in: Advanced Synthesis & Catalysis, 2019, Page(s) 10.1002/adsc.201900234, ISSN 1615-4150
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.201900234

Unravelling nucleophilic aromatic substitution pathways with bimetallic nucleophiles

Author(s): Martí Garçon, Clare Bakewell, Andrew J. P. White, Mark R. Crimmin
Published in: Chemical Communications, Issue 55/12, 2019, Page(s) 1805-1808, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8cc09701a

Functionalisation of Carbon–Fluorine Bonds with Main Group Reagents

Author(s): Mark Crimmin, Wenyi Chen, Clare Bakewell
Published in: Synthesis, Issue 49/04, 2017, Page(s) 810-821, ISSN 0039-7881
Publisher: Georg Thieme Verlag
DOI: 10.1055/s-0036-1588663

Organometallic chemistry using partially fluorinated benzenes

Author(s): Sebastian D. Pike, Mark R. Crimmin, Adrian B. Chaplin
Published in: Chem. Commun., Issue 53/26, 2017, Page(s) 3615-3633, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/C6CC09575E

Addition of Carbon–Fluorine Bonds to a Mg(I)–Mg(I) Bond: An Equivalent of Grignard Formation in Solution

Author(s): Clare Bakewell, Andrew J. P. White, Mark R. Crimmin
Published in: Journal of the American Chemical Society, Issue 138/39, 2016, Page(s) 12763-12766, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.6b08104

The partial dehydrogenation of aluminium dihydrides

Author(s): Thomas N. Hooper, Samantha Lau, Wenyi Chen, Ryan K. Brown, Martí Garçon, Karen Luong, Nathan S. Barrow, Andrew S. Tatton, George A. Sackman, Christopher Richardson, Andrew J. P. White, Richard I. Cooper, Alison J. Edwards, Ian J. Casely, Mark R. Crimmin
Published in: Chemical Science, Issue 10/35, 2019, Page(s) 8083-8093, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sc02750e

Defluorosilylation of Industrially Relevant Fluoroolefins Using Nucleophilic Silicon Reagents

Author(s): Greg Coates, Hui Yee Tan, Carolin Kalff, Andrew J. P. White, Mark R. Crimmin
Published in: Angewandte Chemie International Edition, Issue 58/36, 2019, Page(s) 12514-12518, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201906825

A hexagonal planar transition-metal complex

Author(s): Martí Garçon, Clare Bakewell, George A. Sackman, Andrew J. P. White, Richard I. Cooper, Alison J. Edwards, Mark R. Crimmin
Published in: Nature, Issue 574/7778, 2019, Page(s) 390-393, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1616-2

Dihydridoboranes: Selective Reagents for Hydroboration and Hydrodefluorination

Author(s): Nicholas A. Phillips, James O’Hanlon, Thomas N. Hooper, Andrew J. P. White, Mark R. Crimmin
Published in: Organic Letters, Issue 21/18, 2019, Page(s) 7289-7293, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.9b02515

Defluoroalkylation of sp 3 C−F Bonds of Industrially Relevant Hydrofluoroolefins

Author(s): Nicholas A. Phillips, Gregory J. Coates, Andrew J. P. White, Mark R. Crimmin
Published in: Chemistry – A European Journal, Issue 26/24, 2020, Page(s) 5365-5368, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202000636

Breaking Carbon–Fluorine Bonds with Main Group Nucleophiles

Author(s): Greg Coates, Feriel Rekhroukh, Mark R. Crimmin
Published in: Synlett, Issue 30/20, 2019, Page(s) 2233-2246, ISSN 0936-5214
Publisher: Georg Thieme Verlag
DOI: 10.1055/s-0039-1690738

Activation and Functionalization of C–C σ Bonds of Alkylidene Cyclopropanes at Main Group Centers

Author(s): Richard Y. Kong, Mark R. Crimmin
Published in: Journal of the American Chemical Society, Issue 142/28, 2020, Page(s) 11967-11971, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c03383

Palladium-catalysed C–F alumination of fluorobenzenes: mechanistic diversity and origin of selectivity

Author(s): Feriel Rekhroukh, Wenyi Chen, Ryan K. Brown, Andrew J. P. White, Mark R. Crimmin
Published in: Chemical Science, Issue 11/30, 2020, Page(s) 7842-7849, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc01915a

Group 11 Borataalkene Complexes: Models for Alkene Activation

Author(s): Nicholas A. Phillips; Richard Y. Kong; Andrew J. P. White; Mark R. Crimmin
Published in: Angewandte Chemie (International Ed. in English), Issue 4, 2021, Page(s) 12013-12019, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202100919

Intellectual Property Rights

Patent (1)

Method of HFO synthesis

Application/Publication number: P 254476GB/NE
Date: 2018-06-28
Applicant(s): IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE