Smart Biologics: Developing New Tools in Glycobiology

Project Information

SWEETOOLS

Grant agreement ID: 677465

DOI

10.3030/677465

Project closed

EC signature date 13 January 2016

Start date 1 February 2016

End date 31 July 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 405 625,00

EU contribution

€ 1 405 625,00

Coordinated by

USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.
Czechia

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

An Optimized Protocol for the Synthesis of Peptides Containing trans ‐Cyclooctene and Bicyclononyne Dienophiles as Useful Multifunctional Bioorthogonal Probes

Author(s): Agustina La–Venia, Rastislav Dzijak, Robert Rampmaier, Milan Vrabel
Published in: Chemistry – A European Journal, 2021, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202102042

Structurally Redesigned Bioorthogonal Reagents for Mitochondria-Specific Prodrug Activation

Author(s): Rastislav Dzijak, Juraj Galeta, Arcadio Vázquez, Jaroslav Kozák, Marika Matoušová, Helena Fulka, Martin Dračínský, Milan Vrabel
Published in: JACS Au, Issue 1/1, 2021, Page(s) 23-30, ISSN 2691-3704
Publisher: ACS Publications
DOI: 10.1021/jacsau.0c00053

Stepwise triple-click functionalization of synthetic peptides

Author(s): Anna Kovalová, Radek Pohl, Milan Vrabel
Published in: Organic & Biomolecular Chemistry, Issue 16/33, 2018, Page(s) 5960-5964, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8ob01617h

Design and Synthesis of Aza-Bicyclononene Dienophiles for Rapid Fluorogenic Ligations

Author(s): Sebastian J. Siegl, Arcadio Vázquez, Rastislav Dzijak, Martin Dračínský, Juraj Galeta, Robert Rampmaier, Blanka Klepetářová, Milan Vrabel
Published in: Chemistry - A European Journal, Issue 24/10, 2018, Page(s) 2426-2432, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201705188

An extended approach for the development of fluorogenic trans-cyclooctene-tetrazine cycloadditions

Author(s): Sebastian Joseph Siegl, Juraj Galeta, Rastislav Dzijak, Arcadio Vázquez, Miguel Del Río-Villanueva, Martin Dračínský, Milan Vrabel
Published in: ChemBioChem, 2019, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201800711

Mechanism-Based Fluorogenic trans -Cyclooctene-Tetrazine Cycloaddition

Author(s): Arcadio Vázquez, Rastislav Dzijak, Martin Dračínský, Robert Rampmaier, Sebastian J. Siegl, Milan Vrabel
Published in: Angewandte Chemie International Edition, Issue 56/5, 2017, Page(s) 1334-1337, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201610491

A Systematic Study of Coumarin–Tetrazine Light‐Up Probes for Bioorthogonal Fluorescence Imaging

Author(s): Juraj Galeta, Rastislav Dzijak, Jan Obořil, Martin Dračínský, Milan Vrabel
Published in: Chemistry – A European Journal, 2020, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202001290

Bioorthogonal Fluorescence Turn‐On Labeling Based on Bicyclononyne−Tetrazine Cycloaddition Reactions that Form Pyridazine Products

Author(s): Sebastian J. Siegl, Juraj Galeta, Rastislav Dzijak, Martin Dračínský, Milan Vrabel
Published in: ChemPlusChem, Issue 84/5, 2019, Page(s) 493-497, ISSN 2192-6506
Publisher: Wiley-VCH Verlag
DOI: 10.1002/cplu.201900176