Smart Biologics: Developing New Tools in Glycobiology

Informazioni relative al progetto

SWEETOOLS

ID dell’accordo di sovvenzione: 677465

DOI 10.3030/677465

Progetto chiuso

Data della firma CE 13 Gennaio 2016

Data di avvio 1 Febbraio 2016

Data di completamento 31 Luglio 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 405 625,00

Contributo UE € 1 405 625,00

Coordinato da

USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.
Czechia

Pubblicazioni

Peer reviewed articles (8)

An Optimized Protocol for the Synthesis of Peptides Containing trans ‐Cyclooctene and Bicyclononyne Dienophiles as Useful Multifunctional Bioorthogonal Probes

Autori: Agustina La–Venia, Rastislav Dzijak, Robert Rampmaier, Milan Vrabel
Pubblicato in: Chemistry – A European Journal, 2021, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202102042

Structurally Redesigned Bioorthogonal Reagents for Mitochondria-Specific Prodrug Activation

Autori: Rastislav Dzijak, Juraj Galeta, Arcadio Vázquez, Jaroslav Kozák, Marika Matoušová, Helena Fulka, Martin Dračínský, Milan Vrabel
Pubblicato in: JACS Au, Numero 1/1, 2021, Pagina/e 23-30, ISSN 2691-3704
Editore: ACS Publications
DOI: 10.1021/jacsau.0c00053

Stepwise triple-click functionalization of synthetic peptides

Autori: Anna Kovalová, Radek Pohl, Milan Vrabel
Pubblicato in: Organic & Biomolecular Chemistry, Numero 16/33, 2018, Pagina/e 5960-5964, ISSN 1477-0520
Editore: Royal Society of Chemistry
DOI: 10.1039/c8ob01617h

Design and Synthesis of Aza-Bicyclononene Dienophiles for Rapid Fluorogenic Ligations

Autori: Sebastian J. Siegl, Arcadio Vázquez, Rastislav Dzijak, Martin Dračínský, Juraj Galeta, Robert Rampmaier, Blanka Klepetářová, Milan Vrabel
Pubblicato in: Chemistry - A European Journal, Numero 24/10, 2018, Pagina/e 2426-2432, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201705188

An extended approach for the development of fluorogenic trans-cyclooctene-tetrazine cycloadditions

Autori: Sebastian Joseph Siegl, Juraj Galeta, Rastislav Dzijak, Arcadio Vázquez, Miguel Del Río-Villanueva, Martin Dračínský, Milan Vrabel
Pubblicato in: ChemBioChem, 2019, ISSN 1439-4227
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201800711

Mechanism-Based Fluorogenic trans -Cyclooctene-Tetrazine Cycloaddition

Autori: Arcadio Vázquez, Rastislav Dzijak, Martin Dračínský, Robert Rampmaier, Sebastian J. Siegl, Milan Vrabel
Pubblicato in: Angewandte Chemie International Edition, Numero 56/5, 2017, Pagina/e 1334-1337, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201610491

A Systematic Study of Coumarin–Tetrazine Light‐Up Probes for Bioorthogonal Fluorescence Imaging

Autori: Juraj Galeta, Rastislav Dzijak, Jan Obořil, Martin Dračínský, Milan Vrabel
Pubblicato in: Chemistry – A European Journal, 2020, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202001290

Bioorthogonal Fluorescence Turn‐On Labeling Based on Bicyclononyne−Tetrazine Cycloaddition Reactions that Form Pyridazine Products

Autori: Sebastian J. Siegl, Juraj Galeta, Rastislav Dzijak, Martin Dračínský, Milan Vrabel
Pubblicato in: ChemPlusChem, Numero 84/5, 2019, Pagina/e 493-497, ISSN 2192-6506
Editore: Wiley-VCH Verlag
DOI: 10.1002/cplu.201900176