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Resolution Pharmacology and Physiology of MCTR in Arthritis

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Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology

Author(s): Jesmond Dalli, Charles N Serhan
Published in: British Journal of Pharmacology, 2018, ISSN 0007-1188
DOI: 10.1111/bph.14336

PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function

Author(s): Kimberly Pistorius, Patricia R. Souza, Roberta De Matteis, Shani Austin-Williams, Karoline G. Primdahl, Anders Vik, Francesca Mazzacuva, Romain A. Colas, Raquel M. Marques, Trond V. Hansen, Jesmond Dalli
Published in: Cell Chemical Biology, Issue 25/6, 2018, Page(s) 749-760.e9, ISSN 2451-9456
DOI: 10.1016/j.chembiol.2018.04.017

A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

Author(s): Nguyen TH Mai, Nicholas Dobbs, Nguyen Hoan Phu, Romain A Colas, Le TP Thao, Nguyen TT Thuong, Ho DT Nghia, Nguyen HH Hanh, Nguyen T Hang, A Dorothee Heemskerk, Jeremy N Day, Lucy Ly, Do DA Thu, Laura Merson, Evelyne Kestelyn, Marcel Wolbers, Ronald Geskus, David Summers, Nguyen VV Chau, Jesmond Dalli, Guy E Thwaites
Published in: eLife, Issue 7, 2018, ISSN 2050-084X
DOI: 10.7554/eLife.33478

Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy

Author(s): Stephanie G. Dakin, Lucy Ly, Romain A. Colas, Udo Oppermann, Kim Wheway, Bridget Watkins, Jesmond Dalli, Andrew J. Carr
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
DOI: 10.1038/s41598-017-11188-y

13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis

Author(s): Mary E. Walker, Patricia R. Souza, Romain A. Colas, Jesmond Dalli
Published in: The FASEB Journal, Issue 31/8, 2017, Page(s) 3636-3648, ISSN 0892-6638
DOI: 10.1096/fj.201700268

Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution

Author(s): Jesmond Dalli, Romain A. Colas, Hildur Arnardottir, Charles N. Serhan
Published in: Immunity, Issue 46/1, 2017, Page(s) 92-105, ISSN 1074-7613
DOI: 10.1016/j.immuni.2016.12.009

Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans

Author(s): Krishnaraj S. Rathod, Vikas Kapil, Shanti Velmurugan, Rayomand S. Khambata, Umme Siddique, Saima Khan, Sven Van Eijl, Lorna C. Gee, Jascharanpreet Bansal, Kavi Pitrola, Christopher Shaw, Fulvio D’Acquisto, Romain A. Colas, Federica Marelli-Berg, Jesmond Dalli, Amrita Ahluwalia
Published in: Journal of Clinical Investigation, Issue 127/1, 2017, Page(s) 169-182, ISSN 0021-9738
DOI: 10.1172/JCI89429

Protectin D1 n-3 DPA and resolvin D5 n-3 DPA are effectors of intestinal protection

Author(s): Thomas Gobbetti, Jesmond Dalli, Romain A. Colas, Donata Federici Canova, Marius Aursnes, Delphine Bonnet, Laurent Alric, Nathalie Vergnolle, Celine Deraison, Trond V. Hansen, Charles N. Serhan, Mauro Perretti
Published in: Proceedings of the National Academy of Sciences, Issue 114/15, 2017, Page(s) 3963-3968, ISSN 0027-8424
DOI: 10.1073/pnas.1617290114

Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid

Author(s): Anders Vik, Jesmond Dalli, Trond Vidar Hansen
Published in: Bioorganic & Medicinal Chemistry Letters, Issue 27/11, 2017, Page(s) 2259-2266, ISSN 0960-894X
DOI: 10.1016/j.bmcl.2017.03.079

Resolving inflammation by using nutrition therapy

Author(s): Lucy V. Norling, Lucy Ly, Jesmond Dalli
Published in: Current Opinion in Clinical Nutrition and Metabolic Care, 2016, Page(s) 1, ISSN 1363-1950
DOI: 10.1097/MCO.0000000000000353

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

Author(s): Jesmond Dalli, Iliyan Vlasakov, Ian R. Riley, Ana R. Rodriguez, Bernd W. Spur, Nicos A. Petasis, Nan Chiang, Charles N. Serhan
Published in: Proceedings of the National Academy of Sciences, Issue 113/43, 2016, Page(s) 12232-12237, ISSN 0027-8424
DOI: 10.1073/pnas.1607003113

The novel lipid mediator PD1 n-3 DPA : An overview of the structural elucidation, synthesis, biosynthesis and bioactions

Author(s): Trond Vidar Hansen, Jesmond Dalli, Charles N. Serhan
Published in: Prostaglandins & Other Lipid Mediators, 2017, ISSN 1098-8823
DOI: 10.1016/j.prostaglandins.2017.06.003

Immune resolution mechanisms in inflammatory arthritis

Author(s): Mauro Perretti, Dianne Cooper, Jesmond Dalli, Lucy V. Norling
Published in: Nature Reviews Rheumatology, Issue 13/2, 2017, Page(s) 87-99, ISSN 1759-4790
DOI: 10.1038/nrrheum.2016.193

Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections?

Author(s): Jesmond Dalli
Published in: Molecular Aspects of Medicine, 2017, ISSN 0098-2997
DOI: 10.1016/j.mam.2017.03.007