Magnetic resonance imaging platform for probing fat microstructure

Publications

Peer reviewed articles (18)

MR-Based Assessment of Bone Marrow Fat in Osteoporosis, Diabetes, and Obesity

Author(s): Christian Cordes, Thomas Baum, Michael Dieckmeyer, Stefan Ruschke, Maximilian N. Diefenbach, Hans Hauner, Jan S. Kirschke, Dimitrios C. Karampinos
Published in: Frontiers in Endocrinology, Issue 7, 2016, ISSN 1664-2392
DOI: 10.3389/fendo.2016.00074

B1-insensitive T2 mapping of healthy thigh muscles using a T2-prepared 3D TSE sequence

Author(s): Elisabeth Klupp, Dominik Weidlich, Sarah Schlaeger, Thomas Baum, Barbara Cervantes, Marcus Deschauer, Hendrik Kooijman, Ernst J. Rummeny, Claus Zimmer, Jan S. Kirschke, Dimitrios C. Karampinos
Published in: PLOS ONE, Issue 12/2, 2017, Page(s) e0171337, ISSN 1932-6203
DOI: 10.1371/journal.pone.0171337

Association of proton density fat fraction in adipose tissue with imaging-based and anthropometric obesity markers in adults

Author(s): D Franz, D Weidlich, F Freitag, C Holzapfel, T Drabsch, T Baum, H Eggers, A Witte, E J Rummeny, H Hauner, D C Karampinos
Published in: International Journal of Obesity, 2017, ISSN 0307-0565
DOI: 10.1038/ijo.2017.194

Quantitative MRI and spectroscopy of bone marrow

Author(s): Dimitrios C. Karampinos, Stefan Ruschke, Michael Dieckmeyer, Maximilian Diefenbach, Daniela Franz, Alexandra S. Gersing, Roland Krug, Thomas Baum
Published in: Journal of Magnetic Resonance Imaging, 2017, ISSN 1053-1807
DOI: 10.1002/jmri.25769

Improving chemical shift encoding-based water-fat separation based on a detailed consideration of magnetic field contributions

Author(s): Maximilian N. Diefenbach, Stefan Ruschke, Holger Eggers, Jakob Meineke, Ernst J. Rummeny, Dimitrios C. Karampinos
Published in: Magnetic Resonance in Medicine, Issue 80/3, 2018, Page(s) 990-1004, ISSN 0740-3194
DOI: 10.1002/mrm.27097

Non-invasive Measurement of Brown Fat Metabolism Based on Optoacoustic Imaging of Hemoglobin Gradients

Author(s): Josefine Reber, Monja Willershäuser, Angelos Karlas, Korbinian Paul-Yuan, Gael Diot, Daniela Franz, Tobias Fromme, Saak V. Ovsepian, Nicolas Bézière, Elena Dubikovskaya, Dimitrios C. Karampinos, Christina Holzapfel, Hans Hauner, Martin Klingenspor, Vasilis Ntziachristos
Published in: Cell Metabolism, Issue 27/3, 2018, Page(s) 689-701.e4, ISSN 1550-4131
DOI: 10.1016/j.cmet.2018.02.002

Anatomical Variation of Age-Related Changes in Vertebral Bone Marrow Composition Using Chemical Shift Encoding-Based Water–Fat Magnetic Resonance Imaging

Author(s): Thomas Baum, Alexander Rohrmeier, Jan Syväri, Maximilian N. Diefenbach, Daniela Franz, Michael Dieckmeyer, Andreas Scharr, Hans Hauner, Stefan Ruschke, Jan S. Kirschke, Dimitrios C. Karampinos
Published in: Frontiers in Endocrinology, Issue 9, 2018, ISSN 1664-2392
DOI: 10.3389/fendo.2018.00141

Techniques and Applications of Magnetic Resonance Imaging for Studying Brown Adipose Tissue Morphometry and Function

Author(s): Dimitrios C. Karampinos, Dominik Weidlich, Mingming Wu, Houchun H. Hu, Daniela Franz
Published in: Handbook of Experimental Pharmacology, 2018, ISSN 0171-2004
DOI: 10.1007/164_2018_158

Associations Between Lumbar Vertebral Bone Marrow and Paraspinal Muscle Fat Compositions—An Investigation by Chemical Shift Encoding-Based Water-Fat MRI

Author(s): Nico Sollmann, Michael Dieckmeyer, Sarah Schlaeger, Alexander Rohrmeier, Jan Syvaeri, Maximilian N. Diefenbach, Dominik Weidlich, Stefan Ruschke, Elisabeth Klupp, Daniela Franz, Ernst J. Rummeny, Claus Zimmer, Jan S. Kirschke, Dimitrios C. Karampinos, Thomas Baum
Published in: Frontiers in Endocrinology, Issue 9, 2018, ISSN 1664-2392
DOI: 10.3389/fendo.2018.00563

On the sensitivity of quantitative susceptibility mapping for measuring trabecular bone density

Author(s): Maximilian N. Diefenbach, Jakob Meineke, Stefan Ruschke, Thomas Baum, Alexandra Gersing, Dimitrios C. Karampinos
Published in: Magnetic Resonance in Medicine, 2018, ISSN 0740-3194
DOI: 10.1002/mrm.27531

Automated assessment of paraspinal muscle fat composition based on the segmentation of chemical shift encoding-based water/fat-separated images

Author(s): Thomas Baum, Cristian Lorenz, Christian Buerger, Friedemann Freitag, Michael Dieckmeyer, Holger Eggers, Claus Zimmer, Dimitrios C. Karampinos, Jan S. Kirschke
Published in: European Radiology Experimental, Issue 2/1, 2018, ISSN 2509-9280
DOI: 10.1186/s41747-018-0065-2

Gender- and Age-Related Changes in Trunk Muscle Composition Using Chemical Shift Encoding-Based Water–Fat MRI

Author(s): Egon Burian, Jan Syväri, Christina Holzapfel, Theresa Drabsch, Jan Kirschke, Ernst Rummeny, Claus Zimmer, Hans Hauner, Dimitrios Karampinos, Thomas Baum, Daniela Franz
Published in: Nutrients, Issue 10/12, 2018, Page(s) 1972, ISSN 2072-6643
DOI: 10.3390/nu10121972

Measuring large lipid droplet sizes by probing restricted lipid diffusion effects with diffusion-weighted MRS at 3T

Author(s): Dominik Weidlich, Julius Honecker, Oliver Gmach, Mingming Wu, Rainer Burgkart, Stefan Ruschke, Daniela Franz, Bjoern H. Menze, Thomas Skurk, Hans Hauner, Ulrich Kulozik, Dimitrios C. Karampinos
Published in: Magnetic Resonance in Medicine, Issue 81/6, 2019, Page(s) 3427-3439, ISSN 0740-3194
DOI: 10.1002/mrm.27651

T2 mapping of lumbosacral nerves in patients suffering from unilateral radicular pain due to degenerative disc disease

Author(s): Nico Sollmann, Dominik Weidlich, Barbara Cervantes, Elisabeth Klupp, Carl Ganter, Hendrik Kooijman, Claus Zimmer, Ernst J. Rummeny, Bernhard Meyer, Thomas Baum, Jan S. Kirschke, Dimitrios C. Karampinos
Published in: Journal of Neurosurgery: Spine, 2019, Page(s) 1-9, ISSN 1547-5654
DOI: 10.3171/2018.10.spine181172

Differentiating supraclavicular from gluteal adipose tissue based on simultaneous PDFF and T 2 * mapping using a 20-echo gradient-echo acquisition

Author(s): Daniela Franz, Maximilian N. Diefenbach, Franziska Treibel, Dominik Weidlich, Jan Syväri, Stefan Ruschke, Mingming Wu, Christina Holzapfel, Theresa Drabsch, Thomas Baum, Holger Eggers, Ernst J. Rummeny, Hans Hauner, Dimitrios C. Karampinos
Published in: Journal of Magnetic Resonance Imaging, 2019, ISSN 1053-1807
DOI: 10.1002/jmri.26661

Paraspinal Muscle DTI Metrics Predict Muscle Strength

Author(s): Elisabeth Klupp, Barbara Cervantes, Sarah Schlaeger, Stephanie Inhuber, Florian Kreuzpointer, Ansgar Schwirtz, Alexander Rohrmeier, Michael Dieckmeyer, Dennis M. Hedderich, Maximilian N. Diefenbach, Friedemann Freitag, Ernst J. Rummeny, Claus Zimmer, Jan S. Kirschke, Dimitrios C. Karampinos, Thomas Baum
Published in: Journal of Magnetic Resonance Imaging, 2019, ISSN 1053-1807
DOI: 10.1002/jmri.26679

Texture analysis of vertebral bone marrow using chemical shift encoding–based water-fat MRI: a feasibility study

Author(s): E. Burian, K. Subburaj, M. R. K. Mookiah, A. Rohrmeier, D. M. Hedderich, M. Dieckmeyer, M. N. Diefenbach, S. Ruschke, E. J. Rummeny, C. Zimmer, J. S. Kirschke, D. C. Karampinos, T. Baum
Published in: Osteoporosis International, 2019, ISSN 0937-941X
DOI: 10.1007/s00198-019-04924-9

Lumbar muscle and vertebral bodies segmentation of chemical shift encoding-based water-fat MRI: the reference database MyoSegmenTUM spine

Author(s): Egon Burian, Alexander Rohrmeier, Sarah Schlaeger, Michael Dieckmeyer, Maximilian N. Diefenbach, Jan Syväri, Elisabeth Klupp, Dominik Weidlich, Claus Zimmer, Ernst J. Rummeny, Dimitrios C. Karampinos, Jan S. Kirschke, Thomas Baum
Published in: BMC Musculoskeletal Disorders, Issue 20/1, 2019, ISSN 1471-2474
DOI: 10.1186/s12891-019-2528-x

Conference proceedings (33)

Improving the quality of DW spectra in the supraclavicular fossa with a navigator-gated and cardiac-triggered flow-compensated diffusion-weighted STEAM MRS acquisition

Author(s): Dominik J. Weidlich, Andreas Hock, Stefan Ruschke, Daniela Franz, Hans Hauner, Ernst J. Rummeny, Dimitrios C. Karampinos
Published in: Proc ISMRM 2017, Issue "#5490", 2017

Probing bone marrow adipocyte cell size in vivo at a clinical 3 T scanner using high b-value DW-MRS at long diffusion times

Author(s): Dominik J. Weidlich, Andreas Hock, Stefan Ruschke, Daniela Franz, Katja Steiger, Thomas Skurk, Hans Hauner, Ernst J. Rummeny, Dimitrios C. Karampinos
Published in: Proc ISMRM 2017, Issue "#1227", 2017

Measuring fat unsaturation and polyunsaturation in vertebral bone marrow using dynamic inversion-recovery single-voxel spectroscopy

Author(s): Stefan Ruschke, Andreas Hock, Dominik Weidlich, Ernst J. Rummeny, Jan S. Kirschke, Thomas Baum, Roland Krug, Dimitrios C. Karampinos
Published in: Proc ISMRM 2017, Issue "#5115", 2017

A Generalized Formulation for Parameter Estimation in MR Signals of Multiple Chemical Species

Author(s): Maximilian Nikolaus Diefenbach, Stefan Ruschke, Dimitrios C Karampinos
Published in: Proc ISMRM 2017, Issue "#5181", 2017

Simultaneous R2* and Quantitative Susceptibility Mapping of Trabecularized Yellow Bone Marrow: Initial Results in the Calcaneus

Author(s): Maximilian Nikolaus Diefenbach, Jakob Meineke, Peter Foehr, Stefan Ruschke, Thomas Baum, Jan S Kirschke, Andreas Hock, Hendrik Kooijman, Ernst J Rummeny, Dimitrios C Karampinos
Published in: Proc ISMRM 2017, Issue "#0850", 2017

Supraclavicular and gluteal adipose tissue PDFF is associated to volumes of VAT and SAT and to anthropometric obesity markers in healthy adults

Author(s): Daniela Franz, Dominik Weidlich, Friedemann Freitag, Christina Holzapfel, Thomas Baum, Holger Eggers, Ernst J. Rummeny, Hans Hauner, Dimitrios C. Karampinos
Published in: Proc ISMRM 2017, Issue "#3432", 2017

Anatomical variation of age-related changes in vertebral bone marrow composition using chemical shift encoding-based water-fat MRI

Author(s): Thomas Baum, Alexander Rohrmeier, Jan Syväri, Maximilian N Diefenbach, Daniela Franz, Michael Dieckmeyer, Andreas Scharr, Hans Hauner, Stefan Ruschke, Jan S Kirschke, Dimitrios C Karampinos
Published in: Proc ISMRM 2018, Issue "#1243", 2018

What is the role of MRS-based bone marrow fatty acid unsaturation level compared to fat fraction in predicting vertebral bone strength?

Author(s): Michael Dieckmeyer, Stefan Ruschke, D Anitha, Jan S Kirschke, Dimitrios C Karampinos, Subburaj Karupppasamy, Thomas Baum
Published in: Proc ISMRM 2018, Issue "#5164", 2018

Technical Challenges in Measuring Adipose Tissue T2*

Author(s): Maximilian N. Diefenbach, Franziska Treibel, Daniela Franz, Jan Syväri, Stefan Ruschke, Holger Eggers, Dimitrios C. Karampinos
Published in: Proc ISMRM 2018, Issue "#5612", 2018

On the Sensitivity of Bone Marrow Magnetic Susceptibility and R2* on Trabecular Bone Microstructure

Author(s): Maximilian N. Diefenbach, Anh Van, Jakob Meineke, Jan S. Kirschke, Benedikt Schwaiger, Thomas Baum, Alexandra Gersing, Dimitrios C. Karampinos
Published in: Proc ISMRM 2018, Issue "#0533", 2018

Vertebral Column Quantitative Susceptibility Mapping using Joint Background Field Removal and Dipole Inversion

Author(s): Maximilian N. Diefenbach, Anh Van, Jakob Meineke, Andreas Scharr, Jan S. Kirschke, Alexandra Gersing, Thomas Baum, Benedikt Schwaiger, Dimitrios C. Karampinos
Published in: Proc ISMRM 2018, Issue "#0191", 2018

Differentiating supraclavicular from gluteal adipose tissue based on simultaneous PDFF and T2* mapping using a twenty-echo gradient echo acquisition

Author(s): Daniela Franz, Maximilian N. Diefenbach, Jan Syväri, Dominik Weidlich, Ernst J. Rummeny, Hans Hauner, Stefan Ruschke, Dimitrios C. Karampinos
Published in: Proc ISMRM 2018, Issue "#2498", 2018

The presence of brown adipose tissue is associated with thyroid function in subjects with low and normal BMI

Author(s): Daniela Franz, Dominik Weidlich, Jan Syväri, Maximilian N. Diefenbach, Christina Holzapfel, Theresa Drabsch, Thomas Baum, Holger Eggers, Ernst J. Rummeny, Hans Hauner, Dimitrios C. Karampinos
Published in: Proc ISMRM 2018, Issue "#1266", 2018

Time interleaved multi-gradient-echo imaging with UTE and non-UTE sampling for simultaneous PDFF, T2* and magnetic susceptibility mapping of cortical bone

Author(s): Sophia Kronthaler, Maximilian Nikolaus Diefenbach, Stefan Ruschke, Jakob Meineke, Holger Eggers, Peter Boernert, Dimitrios Karampinos
Published in: Proc ISMRM 2018, Issue "#5157", 2018

Sex dependence of age-related vertebral bone marrow PDFF and T2 relaxation time changes in a cohort of nearly 200 subjects using multi-TE single-voxel MR spectroscopy

Author(s): Jan Syväri, Stefan Ruschke, Michael Dieckmeyer, Daniela Franz, Hans Hauner, Jan S Kirschke, Thomas Baum, Dimitrios Karampinos
Published in: Proc ISMRM 2018, Issue "#5163", 2018

Estimating vertebral bone marrow triglyceride unsaturation based on the extraction of the olefinic peak in short-TE STEAM MRS using a constrained fitting model

Author(s): Jan Syväri, Stefan Ruschke, Michael Dieckmeyer, Daniela Franz, Hans Hauner, Jan S Kirschke, Thomas Baum, Dimitrios Karampinos
Published in: Proc ISMRM 2018, Issue "#5162", 2018

ADC quantification of lipids with high b-value stimulated echo-prepared diffusion-weighted 2D single shot TSE

Author(s): Dominik Weidlich, Stefan Ruschke, Barbara Cervantes, Andreas Hock, Dimitrios C. Karampinos
Published in: Proc ISMRM 2018, Issue "#2511", 2018

In-vivo water T2 mapping in tissues containing water and fat using a T2-prepared 3D Dixon TSE sequence and a pre-calibrated fat spectrum model

Author(s): Dominik Weidlich, Maximilian N. Diefenbach, Sarah Schlaeger, Andreas Hock, Stefan Ruschke, Dimitrios C. Karampinos
Published in: Proc ISMRM 2018, Issue "#4223", 2018

Gender- and age-related changes in trunk muscle composition using chemical shift encoding-based water-fat MRI

Author(s): E. Burian, D. Franz, J. Syväri, C. Holzapfel, T. Drabsch, J. S. Kirschke, E. J. Rummeny, C. Zimmer, H. Hauner, D. C. Karampinos, T. Baum
Published in: Proc ISMRM 2019, Issue "#1278", 2019

Vertebral bone marrow fat content changes in postmenopausal women receiving combined aromatase inhibitor and bisphosphonate therapy after one year, Proc of 27th Scientific Meeting of ISMRM, p. 1304, Montreal, Canada, May 11-16, 2019 (digital poster)

Author(s): M. Dieckmeyer, S. Ruschke, A. Rohrmeier, J. Syväri, I. Einspieler, J. S. Kirschke, E. J. Rummeny, C. Zimmer, D. C. Karampinos, T. Baum
Published in: Proc ISMRM 2019, Issue "#1304", 2019

Regional thigh muscle composition based on chemical shift encoding-based water-fat MRI and its association with muscle strength

Author(s): M. T. Löffler, S. Schlaeger, S. Inhuber, M. Dieckmeyer, D. Weidlich, A. Schwirtz, E. J. Rummeny, C. Zimmer, J. S. Kirschke, D. C. Karampinos, T. Baum
Published in: Proc ISMRM 2019, Issue "#1261", 2019

Accelerated Single-Min-Cut Graph-Cut Algorithm Using a Variable-Layer Graph Construction Improves Field-Mapping in Water–Fat Regions

Author(s): C. Böhm, M. N. Diefenbach, A. Haase, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#4007", 2019

Improved Body Quantitative Susceptibility Mapping by Using a Variable-Layer Single-Min-Cut Graph-Cut Algorithm for Field-Mapping

Author(s): C. Böhm, M. N. Diefenbach, J. Meineke, A. Haase, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#0693", 2019

One-Dimensional k-Space Metrics on Cone Surfaces for Quantitative Susceptibility Mapping

Author(s): M. N. Diefenbach, C. Böhm, J. Meineke, C. Liu, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#0322", 2019

Proton density fat fraction mapping for tracking tissue changes under weight loss in cancer cachexia

Author(s): D. Franz, J. Syväri, C. Zöllner, R. Braren, U. Nitsche, E. J. Rummeny, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#1941", 2019

MRS-based water T2 relaxation time in the supraclavicular fossa relates to anthropometric and imaging obesity markers

Author(s): D. Franz, D. Weidlich, J. Syväri, S. Ruschke, M. Wu, C. Holzapfel, T. Drabsch, E. J. Rummeny, H. Hauner, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#1942", 2019

Trajectory correction for ultrashort echo-time (UTE) imaging based on the measurement of the gradient impulse response function (GIRF) with a thin-slice method

Author(s): S. Kronthaler, J. Rahmer, P. Börnert, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#0924", 2019

Single-voxel short-TR multi-TI multi-TE (SHORTIE) STEAM for water–fat magnetic resonance spectroscopy

Author(s): S. Ruschke, D. Weidlich, M. Wu, A. Hock, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#4230", 2019

T2 mapping of lumbosacral nerves in patients suffering from unilateral radicular pain due to degenerative disc disease

Author(s): N. Sollmann, D. Weidlich, B. Cervantes, E. Klupp, C. Ganter, H. Kooijman, C. Zimmer, E. J. Rummeny, B. Meyer, T. Baum, J. S. Kirschke, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#2874", 2019

Measuring large lipid droplet sizes by probing restricted lipid diffusion effects with Diffusion-Weighted Magnetic Resonance Spectroscopy at 3 T

Author(s): D. Weidlich, J. Honecker, O. Gmach, M. Wu, R. Burgkart, S. Ruschke, D. Franz, B. H. Menze, T. Skurk, H. Hauner, U. Kulozik, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#0373", 2019

Spatially resolved measurement of lipid droplet size in white adipose tissue with high b-value stimulated echo-prepared diffusion-weighted 2D single shot TSE

Author(s): D. Weidlich, M. Wu, S. Ruschke, D. Franz, J. Honecker, O. Gmach, T. Skurk, H. Hauner, U. Kulozik, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#1927", 2019

Compensation of signal loss induced by scanner table vibrations in high b-value DW-TSE for measuring lipids ADC

Author(s): D. Weidlich, S. Ruschke, M. Wu, A. Hock, R. Burgkart, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#3390", 2019

On the Technical Challenges of Diffusion-Weighted MR Spectroscopy for Water ADC Quantification in Human Supraclavicular Fat

Author(s): M. Wu, D. Weidlich, S. Ruschke, D. Franz, D. C. Karampinos
Published in: Proc ISMRM 2019, Issue "#1930", 2019