Chromosomal Common Fragile Sites: Unravelling their biological functions and the basis of their instability

Project Information

CFS modelling

Grant agreement ID: 679068

DOI

10.3030/679068

Project closed

EC signature date 13 January 2016

Start date 1 May 2016

End date 31 July 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 711,00

EU contribution

€ 1 499 711,00

Coordinated by

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Supraphysiological protection from replication stress does not extend mammalian lifespan.

Author(s): Eliene Albers; Alexandra Avram; Mauro Sbroggiò; Oscar Fernandez-Capetillo; Andrés J. López-Contreras
Published in: Aging (Albany NY), Issue 2, 2020, ISSN 1945-4589
Publisher: Impact Journals
DOI: 10.18632/aging.103039

Genetic insights into biological mechanisms governing human ovarian ageing

Author(s): Katherine S. Ruth, Felix R. Day, Jazib Hussain, Ana Martínez-Marchal, Catherine E. Aiken, Ajuna Azad, Deborah J. Thompson, Lucie Knoblochova, Hironori Abe, Jane L. Tarry-Adkins, Javier Martin Gonzalez, Pierre Fontanillas, Annique Claringbould, Olivier B. Bakker, Patrick Sulem, Robin G. Walters, Chikashi Terao, Sandra Turon, Momoko Horikoshi, Kuang Lin, N. Charlotte Onland-Moret, Aditya Sankar, Em
Published in: Nature, 2021, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-021-03779-7

Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

Author(s): Stephanie Munk, Jón Otti Sigurðsson, Zhenyu Xiao, Tanveer Singh Batth, Giulia Franciosa, Louise von Stechow, Andres Joaquin Lopez-Contreras, Alfred Cornelis Otto Vertegaal, Jesper Velgaard Olsen
Published in: Cell Reports, Issue 21/2, 2017, Page(s) 546-558, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2017.09.059

Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

Author(s): Eliene Albers, Mauro Sbroggiò, David Pladevall-Morera, Anna H. Bizard, Alexandra Avram, Patricia Gonzalez, Javier Martin-Gonzalez, Ian D. Hickson, Andres J. Lopez-Contreras
Published in: Cell Reports, Issue 24/12, 2018, Page(s) 3274-3284, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2018.08.071

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

Author(s): David Pladevall-Morera, Stephanie Munk, Andreas Ingham, Lorenza Garribba, Eliene Albers, Ying Liu, Jesper V Olsen, Andres J Lopez-Contreras
Published in: Nucleic Acids Research, 2019, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkz510

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

Author(s): David Pladevall-Morera,María Castejón-Griñán,Paula Aguilera,Karina Gaardahl,Andreas Ingham ,Jacqueline A. Brosnan-Cashman, Alan K. Meeker and Andres J. Lopez-Contreras
Published in: Cancers, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14071790

ATR expands embryonic stem cell fate potential in response to replication stress

Author(s): Sina Atashpaz; Sara Samadi Shams; Javier Martin Gonzalez; Endre Sebestyén; Negar Arghavanifard; Andrea Gnocchi; Eliene Albers; Simone Minardi; Giovanni Faga; Paolo Soffientini; Elisa Allievi; Valeria Cancila; Angela Bachi; Oscar Fernandez-Capetillo; Claudio Tripodo; Francesco Ferrari; Andrés J. López-Contreras; Vincenzo Costanzo
Published in: eLife, Issue 2, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.1101/2020.01.01.888354