BIOengineered grafts for Cartilage Healing In Patients (BIO-CHIP)

Project Information

BIO-CHIP

Grant agreement ID: 681103

DOI 10.3030/681103

Project closed

EC signature date 30 September 2015

Start date 1 November 2015

End date 31 October 2020

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 5 108 273,75

EU contribution € 3 051 836,25

Coordinated by

UNIVERSITAT BASEL
Switzerland

Deliverables

Websites, patent fillings, videos etc. (2)

Video on VuMedi

Videos on VuMedi (video education platform for doctors with over 100’000 participants) will be prepared and uploaded in order to disseminate results of the research to the orthopedic community and in;form them of new surgical techniques.

Public website

Establishment of public website and management structure for its continuous update.

Publications

Peer reviewed articles (4)

Biomarker Signatures of Quality for Engineering Nasal Chondrocyte-Derived Cartilage

Author(s): M. Adelaide Asnaghi, Laura Power, Andrea Barbero, Martin Haug, Ruth Köppl, David Wendt, Ivan Martin
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2020, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2020.00283

Sensing tissue engineered cartilage quality with Raman spectroscopy and statistical learning for the development of advanced characterization assays

Author(s): Laura J. Power, Claudia Fasolato, Andrea Barbero, David J. Wendt, Anke Wixmerten, Ivan Martin, M. Adelaide Asnaghi
Published in: Biosensors and Bioelectronics, Issue 166, 2020, Page(s) 112467, ISSN 0956-5663
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2020.112467

Nasal chondrocytes as a neural crest-derived cell source for regenerative medicine

Author(s): Karoliina Pelttari, Marcus Mumme, Andrea Barbero, Ivan Martin
Published in: Current Opinion in Biotechnology, Issue 47, 2017, Page(s) 1-6, ISSN 0958-1669
Publisher: Elsevier BV
DOI: 10.1016/j.copbio.2017.05.007

Von der Nase ins Knie: 3D-Implantate aus eigenen Knorpelzellen

Author(s): Oliver Pullig, Lena Schubert
Published in: Orthopädie Technik, Issue monthly, 2019, Page(s) 44-47, ISSN 0340-5591
Publisher: Verlag Orthopädie-Technik

Conference proceedings (11)

Successes and hurdles in the translation of tissue engineered products for cartilage repair in clinical trials: focus on regulatory perspectives

Author(s): Asnaghi, M.A., Miot, S., Wixmerten, A., Martin, I
Published in: European Cells and Materials, Issue Vol 31, Suppl 1, 2016, 2016, Page(s) 172, ISSN 1473-2262
Publisher: AO Foundation

Nasal chondrocytes for articular cartilage repair: update on clinical studies.

Author(s): Mumme, M.
Published in: TERMIS- EU 2017: Personalised Therapies for Regenerative Medicine, 2017
Publisher: Davos, Switzerland

Nondestructive Raman Spectroscopy-based quality controls for tissue engineered cartilage

Author(s): Power, L.
Published in: TERMIS World Congress 2018 Integration of Industry, Government, and Academia for Regenerative Medicine, 2018
Publisher: Kyoto, Japan

“Nose to knee”: Nasenknorpel zur Regeneration vom Gelenkknorpel

Author(s): Lehoczky, G.
Published in: AGA Congress, 2018
Publisher: Linz, Austria

From the nose to the knee: engineered nasal cartilage for articular cartilage repair.

Author(s): Martin, I.
Published in: International Stem Cell Conference/International Placenta Stem Cell Society (IPLASS), 2018
Publisher: Bern, Switzerland

Nose2Knee: Clinician's Perspective

Author(s): Ivkovic, A.
Published in: 11TH OSWESTRY CARTILAGE SYMPOSIUM, 2017
Publisher: Oswestry, UK

Tissue Regeneration in Osteoarthritis and Tendinopathy

Author(s): Ivkovic, A.
Published in: Artherex Congress, Subchondral Bone Healing: How to Treat?, 2017
Publisher: BioAcademy 2017

Cartilage injuries

Author(s): Ivkovic, A.
Published in: SportsOrtho a la Carte Congress, 2018, Page(s) 21-23
Publisher: Poreč, Croatia

Molecular and histological characterization of nasal chondrocyte-based cartilage grafts for the treatment of kissing lesions in the knee

Author(s): Marijanović, I.
Published in: 5th Termis World Congress, 2018, Page(s) 133
Publisher: Kyoto, Japan

Cellular communication in 3D, Regeneration of kissing cartilage lesions in the knee using autologous nasal chondrocyte-based cartilage grafts

Author(s): Pušić, M.
Published in: 2nd Annual Meeting, COST Action CA16119 Cellfit, 2018
Publisher: Hvar, Croatia

GMP for Beginners - Wasted time or new impulses for my scientific career?

Author(s): Oliver Pullig
Published in: TERMIS - SYIS ITN Symposium, 2017
Publisher: TERMIS

Thesis and dissertations (1)

Pre-clinical evaluation of chondrocytes in a matrix based cartilage implant (German)

Author(s): Teresa Kilian
Published in: 2016
Publisher: University Würzburg

Book chapters (1)

Roadmap and Challenges for Investigator Initiated Clinical Trials With Advanced Therapy Medicinal Products (ATMPs)

Author(s): Anke Wixmerten, Sylvie Miot, Ivan Martin
Published in: Reference Module in Biomedical Sciences, 2019, Page(s) 57-70, ISBN 9780-128012383
Publisher: Elsevier
DOI: 10.1016/b978-0-12-801238-3.11119-5

Other (1)

BIO-CHIP Phase 2 - klinische Studie zu neuen Knorpelimplantaten vor dem Abschluss

Author(s): Dr. Oliver Pullig
Published in: Fraunhofer ISC Jahresbericht, Issue annual, 2020, Page(s) p65
Publisher: Fraunhofer ISC