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Reversing the epigenetic state of oligodendrocyte precursors cells in multiple sclerosis

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Publications

Single-cell transcriptomic analysis of oligodendrocyte lineage cells

Author(s): David van Bruggen, Eneritz Agirre, Gonçalo Castelo-Branco
Published in: Current Opinion in Neurobiology, Issue 47, 2017, Page(s) 168-175, ISSN 0959-4388
DOI: 10.1016/j.conb.2017.10.005

Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development

Author(s): Sueli Marques, David van Bruggen, Darya Pavlovna Vanichkina, Elisa Mariagrazia Floriddia, Hermany Munguba, Leif Väremo, Stefania Giacomello, Ana Mendanha Falcão, Mandy Meijer, Åsa Kristina Björklund, Jens Hjerling-Leffler, Ryan James Taft, Gonçalo Castelo-Branco
Published in: Developmental Cell, Issue 46/4, 2018, Page(s) 504-517.e7, ISSN 1534-5807
DOI: 10.1016/j.devcel.2018.07.005

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

Author(s): Ana Mendanha Falcão, David van Bruggen, Sueli Marques, Mandy Meijer, Sarah Jäkel, Eneritz Agirre, Samudyata, Elisa M. Floriddia, Darya P. Vanichkina, Charles ffrench-Constant, Anna Williams, André Ortlieb Guerreiro-Cacais, Gonçalo Castelo-Branco
Published in: Nature Medicine, Issue 24/12, 2018, Page(s) 1837-1844, ISSN 1078-8956
DOI: 10.1038/s41591-018-0236-y

RNA velocity of single cells

Author(s): Gioele La Manno, Ruslan Soldatov, Amit Zeisel, Emelie Braun, Hannah Hochgerner, Viktor Petukhov, Katja Lidschreiber, Maria E. Kastriti, Peter Lönnerberg, Alessandro Furlan, Jean Fan, Lars E. Borm, Zehua Liu, David van Bruggen, Jimin Guo, Xiaoling He, Roger Barker, Erik Sundström, Gonçalo Castelo-Branco, Patrick Cramer, Igor Adameyko, Sten Linnarsson, Peter V. Kharchenko
Published in: Nature, Issue 560/7719, 2018, Page(s) 494-498, ISSN 0028-0836
DOI: 10.1038/s41586-018-0414-6

Altered human oligodendrocyte heterogeneity in multiple sclerosis

Author(s): Sarah Jäkel, Eneritz Agirre, Ana Mendanha Falcão, David van Bruggen, Ka Wai Lee, Irene Knuesel, Dheeraj Malhotra, Charles ffrench-Constant, Anna Williams, Gonçalo Castelo-Branco
Published in: Nature, Issue 566/7745, 2019, Page(s) 543-547, ISSN 0028-0836
DOI: 10.1038/s41586-019-0903-2

Single-cell transcriptomic profiling of progenitors of the oligodendrocyte lineage reveals transcriptional convergence during development

Author(s): Sueli Marques, Darya Vanichkina, David van Bruggen, Elisa Floriddia, Hermany Munguba, Leif Varemo, Stefania Giacomello, Ana Mendanha Falcao, Mandy Meijer, S Samudyata, Simone Codeluppi, Asa Bjorklund, Sten Linnarsson, Jens Hjerling-Leffler, Ryan Taft, Goncalo Castelo-Branco
Published in: BioRxiv, 2017
DOI: 10.1101/186445