The physics of antibiotic resistance evolution in spatially-structured multicellular assemblies

Project Information

EvoStruc

Grant agreement ID: 682237

DOI

10.3030/682237

Project closed

EC signature date 15 April 2016

Start date 1 June 2016

End date 31 May 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 826 984,00

EU contribution

€ 1 826 984,00

Coordinated by

THE UNIVERSITY OF EDINBURGH
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (14)

A roadblock-and-kill model explains the action of the DNA-targeting antibiotic ciprofloxacin

Author(s): Angela Dawson; Susana O. L. Direito; Nikola Ojkic; Nikola Ojkic; Rosalind J. Allen; Elin E. Lilja; Bartlomiej Waclaw
Published in: Antimicrobial Agents and Chemotherapy, Issue 2, 2019, ISSN 1098-6596
Publisher: American Society of Microbiology
DOI: 10.1101/791145

Computational design of probes to detect bacterial genomes by multivalent binding

Author(s): Tine Curk, Chris A. Brackley, James D. Farrell, Zhongyang Xing, Darshana Joshi, Susana Direito, Urban Bren, Stefano Angioletti-Uberti, Jure Dobnikar, Erika Eiser, Daan Frenkel, Rosalind J. Allen
Published in: Proceedings of the National Academy of Sciences, Issue 117/16, 2020, Page(s) 8719-8726, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1918274117

Predictable properties of fitness landscapes induced by adaptational tradeoffs

Author(s): Suman G Das, Susana OL Direito, Bartlomiej Waclaw, Rosalind J Allen, Joachim Krug
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.55155

Phenotypic delay in the evolution of bacterial antibiotic resistance: Mechanistic models and their implications

Author(s): Martín Carballo-Pacheco, Michael D. Nicholson, Elin E. Lilja, Rosalind J. Allen, Bartlomiej Waclaw
Published in: PLOS Computational Biology, Issue 16/5, 2020, Page(s) e1007930, ISSN 1553-7358
Publisher: public library of science
DOI: 10.1371/journal.pcbi.1007930

Stability of β-lactam antibiotics in bacterial growth media

Author(s): Rebecca Brouwers, Hugh Vass, Angela Dawson, Tracey Squires, Sharareh Tavaddod, Rosalind J. Allen
Published in: PLOS ONE, Issue 15/7, 2020, Page(s) e0236198, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0236198

Antibiotic resistance: a physicist’s view

Author(s): Rosalind Allen, Bartłomiej Waclaw
Published in: Physical Biology, Issue 13/4, 2016, Page(s) 045001, ISSN 1478-3975
Publisher: Institute of Physics
DOI: 10.1088/1478-3975/13/4/045001

Predicting the dynamics of bacterial growth inhibition by ribosome-targeting antibiotics

Author(s): Philip Greulich, Jakub Doležal, Matthew Scott, Martin R Evans, Rosalind J Allen
Published in: Physical Biology, Issue 14/6, 2017, Page(s) 065005, ISSN 1478-3975
Publisher: Institute of Physics
DOI: 10.1088/1478-3975/aa8001

Reduced adhesion between cells and substrate confers selective advantage in bacterial colonies (a)

Author(s): Craig Watson, Paul Hush, Joshua Williams, Angela Dawson, Nikola Ojkic, Simon Titmuss, Bartlomiej Waclaw
Published in: EPL (Europhysics Letters), Issue 123/6, 2018, Page(s) 68001, ISSN 1286-4854
Publisher: Institute of Physics
DOI: 10.1209/0295-5075/123/68001

Bacterial growth: a statistical physicist’s guide

Author(s): Rosalind J Allen, Bartlomiej Waclaw
Published in: Reports on Progress in Physics, Issue 82/1, 2019, Page(s) 016601, ISSN 0034-4885
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6633/aae546

Growth-dependent drug susceptibility can prevent or enhance spatial expansion of a bacterial population

Author(s): Patrick Sinclair, Martín Carballo-Pacheco, Rosalind J Allen
Published in: Physical Biology, Issue 16/4, 2019, Page(s) 046001, ISSN 1478-3975
Publisher: Institute of Physics
DOI: 10.1088/1478-3975/ab131e

Lineage dynamics in growing biofilms: spatial patterns of standing versus de novo diversity

Author(s): Ellen Young, Rosalind J Allen
Published in: Frontiers in Microbiology, 2022, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2022.915095

A simulation study of aggregation mediated by production of cohesive molecules

Author(s): Gavin Melaugh, Davide Marenduzzo, Alexander Morozov, Rosalind J. Allen
Published in: Soft Matter, Issue 15/44, 2019, Page(s) 9120-9132, ISSN 1744-683X
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sm01462d

Staff and patient perceptions of a community urinary catheter service.

Author(s): Ellen Young; Freya C. Oswald; Fiona C. Denison; Rosalind J. Allen; Meghan Perry; Meghan Perry
Published in: Int J Urol Nurs, Issue 1, 2020, Page(s) 83-91, ISSN 1749-771X
Publisher: Wiley
DOI: 10.1111/ijun.12230

Tracking the stochastic growth of bacterial populations in microfluidic droplets

Author(s): Daniel Taylor, Nia Verdon, Peter Lomax, Rosalind J Allen, Simon Titmuss
Published in: Physical Biology, 2022, ISSN 1478-3975
Publisher: Institute of Physics
DOI: 10.1088/1478-3975/ac4c9b