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Scaling-up biodegradable nanomedicines for multimodal for multimodal precision cancer immunotherapy

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The STEAP1 262-270 peptide encapsulated into PLGA microspheres elicits strong cytotoxic T cell immunity in HLA-A*0201 transgenic mice-A new approach to immunotherapy against prostate carcinoma

Author(s): Valerie L. Herrmann, Daniel E. Wieland, Daniel F. Legler, Valentin Wittmann, Marcus Groettrup
Published in: The Prostate, 76/5, 2016, Page(s) 456-468, ISSN 0270-4137
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/pros.23136

Antibody–Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non–small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade

Author(s): Giuseppe Lo Russo, Massimo Moro, Michele Sommariva, Valeria Cancila, Mattia Boeri, Giovanni Centonze, Simona Ferro, Monica Ganzinelli, Patrizia Gasparini, Veronica Huber, Massimo Milione, Luca Porcu, Claudia Proto, Giancarlo Pruneri, Diego Signorelli, Sabina Sangaletti, Lucia Sfondrini, Chiara Storti, Elena Tassi, Alberto Bardelli, Silvia Marsoni, Valter Torri, Claudio Tripodo, Mario Paolo Colombo
Published in: Clinical Cancer Research, 2018, ISSN 1078-0432
Publisher: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-18-1390

Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma

Author(s): Veronica Huber, Viviana Vallacchi, Viktor Fleming, Xiaoying Hu, Agata Cova, Matteo Dugo, Eriomina Shahaj, Roberta Sulsenti, Elisabetta Vergani, Paola Filipazzi, Angela De Laurentiis, Luca Lalli, Lorenza Di Guardo, Roberto Patuzzo, Barbara Vergani, Elena Casiraghi, Mara Cossa, Ambra Gualeni, Valentina Bollati, Flavio Arienti, Filippo De Braud, Luigi Mariani, Antonello Villa, Peter Altevogt, Viktor
Published in: Journal of Clinical Investigation, 128/12, 2018, Page(s) 5505-5516, ISSN 0021-9738
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci98060

Harnessing Dendritic Cells for Poly (D,L-lactide-co-glycolide) Microspheres (PLGA MS)—Mediated Anti-tumor Therapy

Author(s): Julia Koerner, Dennis Horvath, Marcus Groettrup
Published in: Frontiers in Immunology, 10, 2019, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2019.00707

Microfluidics-Assisted Size Tuning and Biological Evaluation of PLGA Particles

Author(s): Maria Camilla Operti, Yusuf Dölen, Jibbe Keulen, Eric A. W. van Dinther, Carl G. Figdor, Oya Tagit
Published in: Pharmaceutics, 11/11, 2019, Page(s) 590, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11110590

Nanovaccine administration route is critical to obtain pertinent iNKt cell help for robust anti-tumor T and B cell responses

Author(s): Yusuf Dölen, Michael Valente, Oya Tagit, Eliezer Jäger, Eric A. W. Van Dinther, N. Koen van Riessen, Martin Hruby, Uzi Gileadi, Vincenzo Cerundolo, Carl G. Figdor
Published in: OncoImmunology, 9/1, 2020, Page(s) 1738813, ISSN 2162-402X
Publisher: OncoImmunology
DOI: 10.1080/2162402x.2020.1738813

Cross-talk between iNKT cells and CD8 T cells in the spleen requires the IL-4/CCL17 axis for the generation of short-lived effector cells

Author(s): M. Valente, Y. Dölen, E. van Dinther, L. Vimeux, M. Fallet, V. Feuillet, C. G. Figdor
Published in: Proceedings of the National Academy of Sciences, 116/51, 2019, Page(s) 25816-25827, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1913491116