Objective This proposal is for a personalised decision support system for chronic disease management that will make predictions based on real-time data in order to empower individuals to participate in the self-management of their disease. The design will involve users at every stage to ensure that the system meets patient needs and raises clinical outcomes by preventing adverse episodes and improving lifestyle, monitoring and quality of life. Research will be conducted into the development of an innovative adaptive decision support system based on case-based reasoning combined with predictive computer modelling. The tool will offer bespoke advice for self-management by integrating personal health systems with broad and various sources of physiological, lifestyle, environmental and social data. The research will also examine the extent to which human behavioural factors and usability issues have previously hindered the wider adoption of personal guidance systems for chronic disease self-management. It will be developed and validated initially for people with diabetes on basal-bolus insulin therapy, but the underlying approach can be adapted to other chronic diseases. There will be a strong emphasis on safety, with glucose predictions, dose advice, alarms, limits and uncertainties communicated clearly to raise individual awareness of the risk of adverse events such as hypoglycaemia or hyperglycaemia. The outputs of this research will be validated in an ambulatory setting and a key aspect will be innovation management. All components will adhere to medical device standards in order to meet regulatory requirements and ensure interoperability, both with existing personal health systems and commercial products. The resulting architecture will improve interactions with healthcare professionals and provide a generic framework for providing adaptive mobile decision support, with innovation capacity to be applied to other applications, thereby increasing the impact of the project. Fields of science natural sciencescomputer and information sciencesartificial intelligencenatural sciencescomputer and information sciencesinternetinternet of thingsmedical and health sciencesclinical medicineendocrinologydiabetesnatural sciencesbiological sciencesbiochemistrybiomoleculescarbohydratesnatural sciencesmathematicsapplied mathematicsmathematical model Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.4. - Active ageing and self-management of health Topic(s) PHC-28-2015 - Self management of health and disease and decision support systems based on predictive computer modelling used by the patient him or herself Call for proposal H2020-PHC-2014-2015 See other projects for this call Sub call H2020-PHC-2015-single-stage Funding Scheme RIA - Research and Innovation action Coordinator OXFORD BROOKES UNIVERSITY Net EU contribution € 643 013,11 Address Headington campus gipsy lane OX3 OBP Oxford United Kingdom See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (5) Sort alphabetically Sort by Net EU contribution Expand all Collapse all IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom Net EU contribution € 1 198 398,75 Address South kensington campus exhibition road SW7 2AZ London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAT DE GIRONA Spain Net EU contribution € 327 355,00 Address Placa sant domenec 3 17004 Girona See on map Region Este Cataluña Girona Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE GIRONA DOCTOR JOSEP TRUETA Spain Net EU contribution € 651 555,64 Address Calle dr. castany sn edificio de la mancomunidad 2 parque hospitalario marti julia 17190 Girona See on map Region Este Cataluña Girona Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ROMSOFT SRL Romania Net EU contribution € 321 500,00 Address Bulevardul chimiei 2 bis cladire c6 etaj 3 700391 Iasi See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Macroregiunea Doi Nord-Est Iaşi Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CELLNOVO Participation ended United Kingdom Net EU contribution € 406 248,75 Address Buckingham gate 25-28 SW1E 6LD London See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00