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Patient Empowerment through Predictive PERsonalised decision support

Objective

This proposal is for a personalised decision support system for chronic disease management that will make predictions based on real-time data in order to empower individuals to participate in the self-management of their disease. The design will involve users at every stage to ensure that the system meets patient needs and raises clinical outcomes by preventing adverse episodes and improving lifestyle, monitoring and quality of life. Research will be conducted into the development of an innovative adaptive decision support system based on case-based reasoning combined with predictive computer modelling. The tool will offer bespoke advice for self-management by integrating personal health systems with broad and various sources of physiological, lifestyle, environmental and social data. The research will also examine the extent to which human behavioural factors and usability issues have previously hindered the wider adoption of personal guidance systems for chronic disease self-management. It will be developed and validated initially for people with diabetes on basal-bolus insulin therapy, but the underlying approach can be adapted to other chronic diseases. There will be a strong emphasis on safety, with glucose predictions, dose advice, alarms, limits and uncertainties communicated clearly to raise individual awareness of the risk of adverse events such as hypoglycaemia or hyperglycaemia. The outputs of this research will be validated in an ambulatory setting and a key aspect will be innovation management. All components will adhere to medical device standards in order to meet regulatory requirements and ensure interoperability, both with existing personal health systems and commercial products. The resulting architecture will improve interactions with healthcare professionals and provide a generic framework for providing adaptive mobile decision support, with innovation capacity to be applied to other applications, thereby increasing the impact of the project.

Call for proposal

H2020-PHC-2014-2015

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Sub call

H2020-PHC-2015-single-stage

Coordinator

OXFORD BROOKES UNIVERSITY
Net EU contribution
€ 643 013,11
Address
Headington Campus Gipsy Lane
OX3 OBP Oxford
United Kingdom

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (5)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
Net EU contribution
€ 1 198 398,75
Address
South Kensington Campus Exhibition Road
SW7 2AZ London

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSITAT DE GIRONA
Spain
Net EU contribution
€ 327 355,00
Address
Placa Sant Domenec 3
17004 Girona

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Region
Este Cataluña Girona
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE GIRONA DOCTOR JOSEP TRUETA
Spain
Net EU contribution
€ 651 555,64
Address
Calle Dr. Castany Sn Edificio De La Mancomunidad 2 Parque Hospitalario Marti Julia
17190 Girona

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Region
Este Cataluña Girona
Activity type
Research Organisations
Other funding
€ 0,00
ROMSOFT SRL
Romania
Net EU contribution
€ 321 500,00
Address
Bulevardul Chimiei 2 Bis Cladire C6 Etaj 3
700391 Iasi

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Macroregiunea Doi Nord-Est Iaşi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
CELLNOVO

Participation ended

United Kingdom
Net EU contribution
€ 406 248,75
Address
Buckingham Gate 25-28
SW1E 6LD London
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00