Objetivo The estimated cost of getting a new medicine to market is now in excess of $2.6 billion, with an additional $300 million (approx.) typically being directed towards post market approval research and development activities (including testing of new indications, new formulations and new dosage strengths and regimens) (Nature Reviews Drug Discovery 13, 877 (2014)). These costs have increased >145% since 2003, and reflect an increasingly complex process in which there remains a high chance of failure in the expensive later phases of development. With the aim of reducing the times and costs associated with medicine development, increasing attention has focused on the development of approaches to better predict and/or optimize the behaviour of actives and their formulations at an earlier stage of development. Recent research within the School of Pharmacy (University of Nottingham (UoN)) has focussed on the application of advanced surface analytical and biophysical tools to address this need. This proposal will build on this activity via an intersectoral researcher exchange program focussed on supporting future pharmaceutical formulations development.The principal objective of FutForm is to translate the advanced analytical approaches developed within UoN, so that they become embedded into industrial practice for the development of future pharmaceutical processes and therapies. This will be achieved through a collaborative programme of researcher secondments with three small-medium enterprise (SME) companies, each with early stage innovative technologies in areas of importance to the future pharmaceutical industry, namely; enzyme formulations for improved cell isolation (Abiel s.r.l; Italy), nanoparticle platform formulations for oral and topical drug delivery (Inovapotek, Pharmaceutical Research and Development Lda; Portugal) and hydrogel formulations for cell-delivery (Hy2Care b.v.; Netherlands). Ámbito científico medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsengineering and technologynanotechnologynano-materialsmedical and health sciencesmedical biotechnologycells technologiesnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programa(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Tema(s) MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Convocatoria de propuestas H2020-MSCA-RISE-2015 Consulte otros proyectos de esta convocatoria Régimen de financiación MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinador THE UNIVERSITY OF NOTTINGHAM Aportación neta de la UEn € 297 000,00 Dirección University Park NG7 2RD Nottingham Reino Unido Ver en el mapa Región East Midlands (England) Derbyshire and Nottinghamshire Nottingham Tipo de actividad Higher or Secondary Education Establishments Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 297 000,00 Participantes (3) Ordenar alfabéticamente Ordenar por aportación neta de la UE Ampliar todo Contraer todo INOVAPOTEK, PHARMACEUTICAL RESEARCH AND DEVELOPMENT LDA Portugal Aportación neta de la UEn € 36 000,00 Dirección UPTEC - RUA ALFREDO ALLEN 455/461 4200-135 PORTO Ver en el mapa Pyme Organización definida por ella misma como pequeña y mediana empresa (pyme) en el momento de la firma del acuerdo de subvención. Sí Región Continente Norte Área Metropolitana do Porto Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 36 000,00 HY2CARE BV Países Bajos Aportación neta de la UEn € 54 000,00 Dirección URMONDERBAAN 22 6167 RD Geleen Ver en el mapa Pyme Organización definida por ella misma como pequeña y mediana empresa (pyme) en el momento de la firma del acuerdo de subvención. Sí Región Zuid-Nederland Limburg (NL) Zuid-Limburg Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Enlaces Contactar con la organización Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 54 000,00 ABIEL SOCIETA A RESPONSABILITA LIMITATA Italia Aportación neta de la UEn € 27 000,00 Dirección VIALE DELLE SCIENZE SN 90128 Palermo Ver en el mapa Pyme Organización definida por ella misma como pequeña y mediana empresa (pyme) en el momento de la firma del acuerdo de subvención. Sí Región Isole Sicilia Palermo Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Enlaces Contactar con la organización Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 27 000,00
