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Translation of a fluorescent MYelin specific peripheral NERVE tracer

Objective

Tracers that enable imaging of peripheral nerve structures have the potential to reduce the occurrence of perioperative peripheral nerve injury. Hence, through such a fluorescence-guided surgery technique morbidity and related follow up costs may be reduced and the quality of life of patients can be improved. The ability to visualize peripheral nerves also creates nerve-sparing opportunities for surgeons and opens up new commercial-avenues for companies involved in the surgical market. The aim of the MY NERVE ERC-PoC project is to strengthen the IP-position and aid the translation of a new nerve specific tracer. The most promising tracer derived from the ILLUMINATING NERVES ERC-StG, serves as the lead compound in this application. Systematic fine-tuning of this lead will help optimization of the structure-activity relation. Together with compatibility with clinical good manufacturing practice (GMP) production requirements this helps provide a solid basis for future commercialization. The applicant has a multidisciplinary track record in the chemical and (bio)medical field. By driving the clinical translation of new imaging tracers, his research group already has made significant contributions to the field of fluorescence guided surgery. Combined with legal support regarding IP-position, feedback from end-users (surgeons), and industrial partners with a global leading position in the surgical market, this background will ensure a translational approach. Ultimately, bridging the gap between synthetic chemical developments and the clinical demand for fluorescent tracers should help accomplish patient benefit.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-POC - Proof of Concept Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2015-PoC

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Host institution

ACADEMISCH ZIEKENHUIS LEIDEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 140 000,00
Address
ALBINUSDREEF 2
2333 ZA Leiden
Netherlands

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Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 140 000,00

Beneficiaries (1)

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