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CORDIS

Translation of a fluorescent MYelin specific peripheral NERVE tracer

Ziel

Tracers that enable imaging of peripheral nerve structures have the potential to reduce the occurrence of perioperative peripheral nerve injury. Hence, through such a fluorescence-guided surgery technique morbidity and related follow up costs may be reduced and the quality of life of patients can be improved. The ability to visualize peripheral nerves also creates nerve-sparing opportunities for surgeons and opens up new commercial-avenues for companies involved in the surgical market. The aim of the MY NERVE ERC-PoC project is to strengthen the IP-position and aid the translation of a new nerve specific tracer. The most promising tracer derived from the ILLUMINATING NERVES ERC-StG, serves as the lead compound in this application. Systematic fine-tuning of this lead will help optimization of the structure-activity relation. Together with compatibility with clinical good manufacturing practice (GMP) production requirements this helps provide a solid basis for future commercialization. The applicant has a multidisciplinary track record in the chemical and (bio)medical field. By driving the clinical translation of new imaging tracers, his research group already has made significant contributions to the field of fluorescence guided surgery. Combined with legal support regarding IP-position, feedback from end-users (surgeons), and industrial partners with a global leading position in the surgical market, this background will ensure a translational approach. Ultimately, bridging the gap between synthetic chemical developments and the clinical demand for fluorescent tracers should help accomplish patient benefit.

Wissenschaftliches Gebiet (EuroSciVoc)

Programm/Programme

Thema/Themen

Finanzierungsplan

ERC-POC - Proof of Concept Grant

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Aufforderung zur Vorschlagseinreichung

(öffnet in neuem Fenster) ERC-2015-PoC

Alle im Rahmen dieser Aufforderung zur Einreichung von Vorschlägen finanzierten Projekte anzeigen

Gastgebende Einrichtung

ACADEMISCH ZIEKENHUIS LEIDEN
Netto-EU-Beitrag
€ 140 000,00
Adresse
ALBINUSDREEF 2
2333 ZA Leiden
Niederlande
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 140 000,00

Begünstigte (1)