Amorphous and Evolutionary DNA Nanotechnology

Publicaciones

Establishing Communication Between Artificial Cells

Autores: Lukas Aufinger, Friedrich C. Simmel
Publicado en: Chemistry – A European Journal, Edición 25/55, 2019, Página(s) 12659-12670, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201901726

Bacterial Growth, Communication, and Guided Chemotaxis in 3D-Bioprinted Hydrogel Environments

Autores: Julia Müller, Anna C. Jäkel, Jonathan Richter, Markus Eder, Elisabeth Falgenhauer, and Friedrich C. Simmel
Publicado en: ACS Applied Materials and Interfaces, 2022, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.1c20836

Riboswitch-inspired toehold riboregulators for gene regulation in <i>Escherichia coli</i>

Autores: Tianhe Wang; Friedrich C Simmel
Publicado en: Nucleic Acids Research, Edición 03051048, 2022, Página(s) 4784–4798, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkac275

Genetically Encoded Membranes for Bottom‐Up Biology

Autores: Kilian Vogele, Tobias Pirzer, Friedrich C. Simmel
Publicado en: ChemSystemsChem, Edición 1/4, 2019, ISSN 2570-4206
Editor: Wiley-VCH
DOI: 10.1002/syst.201900016

Single Cell Characterization of a Synthetic Bacterial Clock with a Hybrid Feedback Loop Containing dCas9-sgRNA

Autores: John Henningsen, Matthaeus Schwarz-Schilling, Andreas Leibl, Joaquı́n Gutiérrez, Sandra Sagredo, and Friedrich C. Simmel
Publicado en: ACS Synthetic BIology, 2020, ISSN 2161-5063
Editor: American Chemical Society
DOI: 10.1021/acssynbio.0c00438

Programming Diffusion and Localization of DNA Signals in 3D‐Printed DNA‐Functionalized Hydrogels

Autores: Julia Müller, Anna Christina Jäkel, Dominic Schwarz, Lukas Aufinger, Friedrich C. Simmel
Publicado en: Small, Edición 16/31, 2020, Página(s) 2001815, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202001815

Single DNA Origami Detection by Nanoimpact Electrochemistry

Autores: Evangelina Pensa, Yash Bogawat, Friedrich C. Simmel, Ibon Santiago
Publicado en: ChemElectroChem, 2022, ISSN 2196-0216
Editor: Wiley-VCH
DOI: 10.1002/celc.202101696

A low-cost fluorescence reader for in vitro transcription and nucleic acid detection with Cas13a

Autores: Florian Katzmeier, Lukas Aufinger, Aurore Dupin, Jorge Quintero, Matthias Lenz, Ludwig Bauer, Sven Klumpe, Dawafuti Sherpa, Benedikt Dürr, Maximilian Honemann, Igor Styazhkin, Friedrich C. Simmel, Michael Heymann
Publicado en: PLOS ONE, Edición 14/12, 2019, Página(s) e0220091, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0220091

Emergence of Colloidal Patterns in ac Electric Fields

Autores: Florian Katzmeier, Bernhard Altaner, Jonathan List, Ulrich Gerland, and Friedrich C. Simmel
Publicado en: Physical Review Letters, 2022, ISSN 0031-9007
Editor: American Physical Society
DOI: 10.1103/physrevlett.128.058002

Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-binding cavities

Autores: Ali Aghebat Rafat, Sandra Sagredo, Melissa Thalhammer, Friedrich C. Simmel
Publicado en: Nature Chemistry, Edición 12/9, 2020, Página(s) 852-859, ISSN 1755-4330
Editor: Nature Publishing Group
DOI: 10.1038/s41557-020-0504-6

Synthetic cell–based materials extract positional information from morphogen gradients

Autores: Aurore Dupin, Lukas Aufinger, Igor Styazhkin, Florian Rothfischer, Benedikt K. Kaufmann, Sascha Schwarz, Nikolas Galensowske, Hauke Clausen-Schaumann, Friedrich C. Simmel
Publicado en: Science Advances, 2022, ISSN 2375-2548
Editor: AAAS
DOI: 10.1126/sciadv.abl9228

Steady-State Operationof a Cell-Free Genetic Band-Detection Circuit

Autores: Anna Jäkel, Lukas Aufinger, Friedrich C. Simmel
Publicado en: ACS Synthetic Biology, Edición 21615063, 2022, ISSN 2161-5063
Editor: American Chemical Society
DOI: 10.1021/acssynbio.2c00195

Growth of Giant Peptide Vesicles Driven by Compartmentalized Transcription–Translation Activity

Autores: Thomas Frank, Kilian Vogele, Aurore Dupin, Friedrich C. Simmel, Tobias Pirzer
Publicado en: Chemistry – A European Journal, Edición 26/72, 2020, Página(s) 17356-17360, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202003366

Transcriptional Interference in Toehold Switch-Based RNA Circuits

Autores: Elisabeth Falgenhauer, Andrea Mückl, Matthaeus Schwarz-Schilling, and Friedrich C. Simmel
Publicado en: ACS Synthetic Biology, 2022, ISSN 2161-5063
Editor: American Chemical Society
DOI: 10.1021/acssynbio.1c00486

Self-organizing materials built with DNA

Autores: Friedrich C. Simmel, Rebecca Schulman
Publicado en: MRS Bulletin, Edición 42/12, 2017, Página(s) 913-919, ISSN 0883-7694
Editor: Materials Research Society
DOI: 10.1557/mrs.2017.271

A DNA Nanorobot Uprises against Cancer

Autores: Hari R. Singh, Enzo Kopperger, Friedrich C. Simmel
Publicado en: Trends in Molecular Medicine, Edición 24/7, 2018, Página(s) 591-593, ISSN 1471-4914
Editor: Elsevier BV
DOI: 10.1016/j.molmed.2018.05.001

Artificial Gel-Based Organelles for Spatial Organization of Cell-Free Gene Expression Reactions

Autores: Lukas Aufinger, Friedrich C. Simmel
Publicado en: Angewandte Chemie International Edition, Edición 57/52, 2018, Página(s) 17245-17248, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201809374

Towards synthetic cells using peptide-based reaction compartments

Autores: Kilian Vogele, Thomas Frank, Lukas Gasser, Marisa A. Goetzfried, Mathias W. Hackl, Stephan A. Sieber, Friedrich C. Simmel, Tobias Pirzer
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-06379-8

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography

Autores: Günther Pardatscher, Matthaeus Schwarz-Schilling, Sandra Sagredo, Friedrich C. Simmel
Publicado en: Journal of Visualized Experiments, Edición 140, 2018, ISSN 1940-087X
Editor: MYJoVE Corporation
DOI: 10.3791/58634

Signalling and differentiation in emulsion-based multi-compartmentalized in vitro gene circuits

Autores: Aurore Dupin, Friedrich C. Simmel
Publicado en: Nature Chemistry, Edición 11/1, 2019, Página(s) 32-39, ISSN 1755-4330
Editor: Nature Publishing Group
DOI: 10.1038/s41557-018-0174-9

Out-of-Plane Aptamer Functionalization of RNA Three-Helix Tiles

Autores: Aradhana Chopra, Sandra Sagredo, Guido Grossi, Ebbe Andersen, Friedrich Simmel
Publicado en: Nanomaterials, Edición 9/4, 2019, Página(s) 507, ISSN 2079-4991
Editor: MDPI
DOI: 10.3390/nano9040507

Switching the activity of Cas12a using guide RNA strand displacement circuits

Autores: Lukas Oesinghaus, Friedrich C. Simmel
Publicado en: Nature Communications, Edición 10/1, 2019, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-09953-w

Principles and Applications of Nucleic Acid Strand Displacement Reactions

Autores: Friedrich C. Simmel, Bernard Yurke, Hari R. Singh
Publicado en: Chemical Reviews, Edición 119, 2019, Página(s) 6326-6369, ISSN 0009-2665
Editor: American Chemical Society
DOI: 10.1021/acs.chemrev.8b00580

Controlling Chirality across Length Scales using DNA

Autores: Alessandro Cecconello, Friedrich C. Simmel
Publicado en: Small, Edición 15, 2019, Página(s) 1805419, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201805419

Algorithmic Design of 3D Wireframe RNA Polyhedra

Autores: Antti Elonen, Ashwin Karthick Natarajan, Ibuki Kawamata, Lukas Oesinghaus, Abdulmelik Mohammed, Jani Seitsonen, Yuki Suzuki, Friedrich C. Simmel, Anton Kuzyk, and Pekka Orponen
Publicado en: ACS Nano, Edición 19360851, 2022, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.2c06035

Complex dynamics in a synchronized cell-free genetic clock

Autores: Lukas Aufinger, Johann Brenner, Friedrich C. SImmel
Publicado en: Nature Communications, Edición 20411723, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-30478-2

Rational design of hybrid DNA–RNA triplex structures as modulators of transcriptional activity <i>in vitro</i>

Autores: Alessandro Cecconello; Massimiliano Magro; Fabio Vianello; Friedrich C Simmel
Publicado en: Nucleic Acids Research, Edición 50, 2023, Página(s) 13172–13182, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkac1131

Controlling gene expression in mammalian cells using multiplexed conditional guide RNAs for Cas12a

Autores: Lukas Oesinghaus; Friedrich C. Simmel
Publicado en: Angewandte Chemie Int. Ed., Edición 60, 2021, Página(s) 23894-23902, ISSN 0044-8249
Editor: Wiley-VCH
DOI: 10.1101/2021.04.16.440136

Small Antisense DNA-Based Gene Silencing Enables Cell-Free Bacteriophage Manipulation and Genome Replication

Autores: Kilian Vogele, Elisabeth Falgenhauer, Sophie von Schönberg, Friedrich C. Simmel, Tobias Pirzer
Publicado en: ACS Synthetic Biology, Edición 10/3, 2021, Página(s) 459-465, ISSN 2161-5063
Editor: American Chemical Society
DOI: 10.1021/acssynbio.0c00402

Evaluation of an E. coli cell extract prepared by lysozyme‐assisted sonication via gene expression, phage assembly and proteomics

Autores: Elisabeth Falgenhauer, Sophie von Schönberg, Chen Meng, Andrea Mückl, Kilian Vogele, Quirin Emslander, Christina Ludwig, Friedrich Christian Simmel
Publicado en: ChemBioChem, 2021, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202100257

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