Blood Vessel Development and Homeostasis: Identification and Functional Analysis of Genetic Modifiers

Publicaciones

Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract

Autores: Giulia LM Boezio, Anabela Bensimon-Brito, Janett Piesker, Stefan Guenther, Christian SM Helker, Didier YR Stainier
Publicado en: eLife, Edición 9, 2020, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.57603

Parental mutations influence wild-type offspring via transcriptional adaptation

Autores: Zhen Jiang, Mohamed A El-Brolosy, Vahan Serobyan, Jordan M Welker, Nicholas Retzer, Christopher M Dooley, Gabrielius Jakutis, Thomas Juan, Nana Fukuda, Hans-Martin Maischein, Darius Balciunas, Didier Y R Stainier
Publicado en: Science Advances, Edición 8, 2022, ISSN 2375-2548
Editor: American Association for the Advancement of Science - AAAS
DOI: 10.1126/sciadv.abj2029

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

Autores: Christian S.M. Helker, Jean Eberlein, Kerstin Wilhelm, Toshiya Sugino, Julian Malchow, Annika Schuermann, Stefan Baumeister, Hyouk-Bum Kwon, Hans-Martin Maischein, Michael Potente, Wiebke Herzog, Didier Y.R. Stainier
Publicado en: eLife, Edición 10, 2020, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.55589

Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures.

Autores: Konstantinos Gkatzis, Paolo Panza, Sofia Peruzzo, Didier Y.R. Stainier
Publicado en: eLife, Edición 10, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.65811

Partial sequence identity in a 25-nucleotide long element is sufficient for transcriptional adaptation in the Caenorhabditis elegans act-5/act-3 model

Autores: Jordan M. Welker, Vahan Serobyan, Elhamalsadat Zaker Esfahani, Didier Y. R. Stainier
Publicado en: PLoS Genetics, Edición 19, 2023, ISSN 1553-7404
Editor: Public Library of Science
DOI: 10.1371/journal.pgen.1010806

Induction of interferon-stimulated genes and cellular stress pathways by morpholinos in zebrafish

Autores: Jason K.H. Lai, Kristina K. Gagalova, Carsten Kuenne, Mohamed A. El-Brolosy, Didier Y.R. Stainier
Publicado en: Developmental Biology, 2019, ISSN 0012-1606
Editor: Academic Press
DOI: 10.1016/j.ydbio.2019.06.008

Genetic compensation triggered by mutant mRNA degradation

Autores: Mohamed A. El-Brolosy, Zacharias Kontarakis, Andrea Rossi, Carsten Kuenne, Stefan Günther, Nana Fukuda, Khrievono Kikhi, Giulia L. M. Boezio, Carter M. Takacs, Shih-Lei Lai, Ryuichi Fukuda, Claudia Gerri, Antonio J. Giraldez, Didier Y. R. Stainier
Publicado en: Nature, Edición 568/7751, 2019, Página(s) 193-197, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-019-1064-z

Immune responses in cardiac repair and regeneration: a comparative point of view

Autores: Shih-Lei Lai, Rubén Marín-Juez, Didier Y. R. Stainier
Publicado en: Cellular and Molecular Life Sciences, Edición 76/7, 2019, Página(s) 1365-1380, ISSN 1420-682X
Editor: Birkhauser Verlag
DOI: 10.1007/s00018-018-2995-5

The Max Planck Institute for Heart and Lung Research Curiosity-Driven Basic Research to Fight Cardio-Pulmonary Diseases

Autores: Thomas Braun, Stefan Offermanns, Didier Y.R. Stainier, Werner Seeger
Publicado en: Circulation Research, Edición 120/9, 2017, Página(s) 1386-1389, ISSN 0009-7330
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.117.310763

Transcriptional adaptation in Caenorhabditis elegans

Autores: Vahan Serobyan, Zacharias Kontarakis, Mohamed A El-Brolosy, Jordan M Welker, Oleg Tolstenkov, Amr M Saadeldein, Nicholas Retzer, Alexander Gottschalk, Ann M Wehman, Didier YR Stainier
Publicado en: eLife, Edición 9, 2020, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.50014

Tek (Tie2) is not required for cardiovascular development in zebrafish

Autores: Zhen Jiang, Claudia Carlantoni, Srinivas Allanki, Ingo Ebersberger, Didier Y.R. Stainier
Publicado en: Development, Edición 147, 2020, ISSN 0950-1991
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dev.193029

Genetics in Light of Transcriptional Adaptation.

Autores: Zacharias Kontarakis, Didier Y.R. Stainier
Publicado en: Trends in Genetics, Edición 36, 2020, ISSN 0168-9525
Editor: Elsevier BV
DOI: 10.1016/j.tig.2020.08.008

Genotype–Phenotype Relationships in the Context of Transcriptional Adaptation and Genetic Robustness

Autores: Gabrielius Jakutis, Didier Y.R. Stainier
Publicado en: Annual Review of Genetics, Edición 55/1, 2021, Página(s) 71-91, ISSN 0066-4197
Editor: Annual Reviews, Inc.
DOI: 10.1146/annurev-genet-071719-020342

Genetic compensation: A phenomenon in search of mechanisms

Autores: Mohamed A. El-Brolosy, Didier Y. R. Stainier
Publicado en: PLOS Genetics, Edición 13/7, 2017, Página(s) e1006780, ISSN 1553-7404
Editor: Public Library of Science
DOI: 10.1371/journal.pgen.1006780

Loss-of-function genetic tools for animal models: cross-species and cross-platform differences

Autores: Benjamin E. Housden, Matthias Muhar, Matthew Gemberling, Charles A. Gersbach, Didier Y. R. Stainier, Geraldine Seydoux, Stephanie E. Mohr, Johannes Zuber, Norbert Perrimon
Publicado en: Nature Reviews Genetics, Edición 18/1, 2017, Página(s) 24-40, ISSN 1471-0056
Editor: Nature Publishing Group
DOI: 10.1038/nrg.2016.118

Recent insights into vascular development from studies in zebrafish

Autores: Ryota L. Matsuoka, Didier Y.R. Stainier
Publicado en: Current Opinion in Hematology, 2018, Página(s) 1, ISSN 1065-6251
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/moh.0000000000000420

Transcriptional adaptation: a mechanism underlying genetic robustness

Autores: Tamar E. Sztal, Didier Y. R. Stainier
Publicado en: Development, Edición 147/15, 2020, ISSN 0950-1991
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dev.186452

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