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Chromatin Adaptations through Interactions of Chaperones in Time


JMJD1B, a novel player in histone H3 and H4 processing to ensure genome stability

Author(s): Francisco Saavedra, Zachary A. Gurard-Levin, Camila Rojas-Villalobos, Isabelle Vassias, Raquel Quatrini, Geneviève Almouzni, Alejandra Loyola
Published in: Epigenetics & Chromatin, Issue 13/1, 2020, ISSN 1756-8935
DOI: 10.1186/s13072-020-00331-1

Two HIRA-dependent pathways mediate H3.3 de novo deposition and recycling during transcription

Author(s): Júlia Torné, Dominique Ray-Gallet, Ekaterina Boyarchuk, Mickaël Garnier, Patricia Le Baccon, Antoine Coulon, Guillermo A. Orsi, Geneviève Almouzni
Published in: Nature Structural & Molecular Biology, Issue 27/11, 2020, Page(s) 1057-1068, ISSN 1545-9993
DOI: 10.1038/s41594-020-0492-7

Combining epigenetic drugs with other therapies for solid tumours — past lessons and future promise

Author(s): Daphné Morel, Daniel Jeffery, Sandrine Aspeslagh, Geneviève Almouzni, Sophie Postel-Vinay
Published in: Nature Reviews Clinical Oncology, Issue 17/2, 2020, Page(s) 91-107, ISSN 1759-4774
DOI: 10.1038/s41571-019-0267-4

Regulation of ALT-associated homology-directed repair by polyADP-ribosylation

Author(s): Song My Hoang, Nicole Kaminski, Ragini Bhargava, Jonathan Barroso-González, Michelle L. Lynskey, Laura García-Expósito, Justin L. Roncaioli, Anne R. Wondisford, Callen T. Wallace, Simon C. Watkins, Dominic I. James, Ian D. Waddell, Donald Ogilvie, Kate M. Smith, Felipe da Veiga Leprevost, Dattatreya Mellacharevu, Alexey I. Nesvizhskii, Jianfeng Li, Dominique Ray-Gallet, Robert W. Sobol, Genevie
Published in: Nature Structural & Molecular Biology, Issue 27/12, 2020, Page(s) 1152-1164, ISSN 1545-9993
DOI: 10.1038/s41594-020-0512-7

Essential role for centromeric factors following p53 loss and oncogenic transformation

Author(s): Dan Filipescu, Monica Naughtin, Katrina Podsypanina, Vincent Lejour, Laurence Wilson, Zachary A. Gurard-Levin, Guillermo A. Orsi, Iva Simeonova, Eleonore Toufektchan, Laura D. Attardi, Franck Toledo, Geneviève Almouzni
Published in: Genes & Development, Issue 31/5, 2017, Page(s) 463-480, ISSN 0890-9369
DOI: 10.1101/gad.290924.116

Shaping Chromatin in the Nucleus: The Bricks and the Architects

Author(s): David Sitbon, Katrina Podsypanina, Tejas Yadav, Geneviève Almouzni
Published in: Cold Spring Harbor Symposia on Quantitative Biology, 2017, Page(s) 033753, ISSN 0091-7451
DOI: 10.1101/sqb.2017.82.033753

PP32 and SET/TAF-Iβ proteins regulate the acetylation of newly synthesized histone H4

Author(s): Francisco Saavedra, Carlos Rivera, Elizabeth Rivas, Paola Merino, Daniel Garrido, Sergio Hernández, Ignasi Forné, Isabelle Vassias, Zachary A. Gurard-Levin, Iván E. Alfaro, Axel Imhof, Geneviève Almouzni, Alejandra Loyola
Published in: Nucleic Acids Research, Issue 45/20, 2017, Page(s) 11700-11710, ISSN 0305-1048
DOI: 10.1093/nar/gkx775

Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit

Author(s): Dominique Ray-Gallet, M. Daniel Ricketts, Yukari Sato, Kushol Gupta, Ekaterina Boyarchuk, Toshiya Senda, Ronen Marmorstein, Geneviève Almouzni
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
DOI: 10.1038/s41467-018-05581-y

Chromatin plasticity: A versatile landscape that underlies cell fate and identity

Author(s): Tejas Yadav, Jean-Pierre Quivy, Geneviève Almouzni
Published in: Science, Issue 361/6409, 2018, Page(s) 1332-1336, ISSN 0036-8075
DOI: 10.1126/science.aat8950

High-resolution visualization of H3 variants during replication reveals their controlled recycling

Author(s): Camille Clément, Guillermo A. Orsi, Alberto Gatto, Ekaterina Boyarchuk, Audrey Forest, Bassam Hajj, Judith Miné-Hattab, Mickaël Garnier, Zachary A. Gurard-Levin, Jean-Pierre Quivy, Geneviève Almouzni
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
DOI: 10.1038/s41467-018-05697-1

Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure

Author(s): Marie-Therese El-Daher, Nicolas Cagnard, Marine Gil, Marie Chansel Da Cruz, Claire Leveau, Fernando Sepulveda, Mohammed Zarhrate, Frédéric Tores, Patricia Legoix, Sylvain Baulande, Jean Pierre de Villartay, Geneviève Almouzni, Jean-Pierre Quivy, Alain Fischer, Geneviève de Saint Basile
Published in: Cell Discovery, Issue 4/1, 2018, ISSN 2056-5968
DOI: 10.1038/s41421-018-0061-y

Insights into the molecular architecture and histone H3-H4 deposition mechanism of yeast Chromatin assembly factor 1

Author(s): Paul Victor Sauer, Jennifer Timm, Danni Liu, David Sitbon, Elisabetta Boeri-Erba, Christophe Velours, Norbert Mücke, Jörg Langowski, Françoise Ochsenbein, Geneviève Almouzni, Daniel Panne
Published in: eLife, Issue 6, 2017, ISSN 2050-084X
DOI: 10.7554/elife.23474

POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication

Author(s): Roberto Bellelli, Ondrej Belan, Valerie E. Pye, Camille Clement, Sarah L. Maslen, J. Mark Skehel, Peter Cherepanov, Genevieve Almouzni, Simon J. Boulton
Published in: Molecular Cell, Issue 72/1, 2018, Page(s) 112-126.e5, ISSN 1097-2765
DOI: 10.1016/j.molcel.2018.08.043

Histone supply: Multitiered regulation ensures chromatin dynamics throughout the cell cycle

Author(s): Shweta Mendiratta, Alberto Gatto, Genevieve Almouzni
Published in: The Journal of Cell Biology, 2018, Page(s) jcb.201807179, ISSN 0021-9525
DOI: 10.1083/jcb.201807179

KAP1 facilitates reinstatement of heterochromatin after DNA replication

Author(s): Suk Min Jang, Annamaria Kauzlaric, Jean-Pierre Quivy, Julien Pontis, Benjamin Rauwel, Andrea Coluccio, Sandra Offner, Julien Duc, Priscilla Turelli, Geneviève Almouzni, Didier Trono
Published in: Nucleic Acids Research, Issue 46/17, 2018, Page(s) 8788-8802, ISSN 0305-1048
DOI: 10.1093/nar/gky580

The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells

Author(s): Charles Ng, Martin Aichinger, Tung Nguyen, Christy Au, Tariq Najar, Lin Wu, Kai R. Mesa, Will Liao, Jean-Pierre Quivy, Benjamin Hubert, Genevieve Almouzni, Johannes Zuber, Dan R. Littman
Published in: Genes & Development, Issue 33/11-12, 2019, Page(s) 669-683, ISSN 0890-9369
DOI: 10.1101/gad.322024.118

Dynamics of Asymmetric and Symmetric Divisions of Muscle Stem Cells In Vivo and on Artificial Niches

Author(s): Brendan Evano, Sara Khalilian, Gilles Le Carrou, Geneviève Almouzni, Shahragim Tajbakhsh
Published in: Cell Reports, Issue 30/10, 2020, Page(s) 3195-3206.e7, ISSN 2211-1247
DOI: 10.1016/j.celrep.2020.01.097

Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway

Author(s): David Sitbon, Ekaterina Boyarchuk, Florent Dingli, Damarys Loew, Geneviève Almouzni
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-15084-4

Metabolic Deregulations Affecting Chromatin Architecture: One-Carbon Metabolism and Krebs Cycle Impact Histone Methylation

Author(s): Francisco Saavedra, Ekaterina Boyarchuk, Francisca Alvarez, Geneviève Almouzni, Alejandra Loyola
Published in: The DNA, RNA, and Histone Methylomes, 2019, Page(s) 573-606
DOI: 10.1007/978-3-030-14792-1_23

Imaging Newly Synthesized and Old Histone Variant Dynamics Dependent on Chaperones Using the SNAP-Tag System

Author(s): Júlia Torné, Guillermo A. Orsi, Dominique Ray-Gallet, Geneviève Almouzni
Published in: Histone Variants - Methods and Protocols, Issue 1832, 2018, Page(s) 207-221
DOI: 10.1007/978-1-4939-8663-7_11