Objetivo Migratory birds have evolved exceptional adaptations: they can invert their circadian rhythms turning from diurnal to nocturnal, undergo rapid changes in body mass and fat stores, and cope with repeated cycles of fasting and feeding as they alternate between sustained migratory flights and refuelling stopovers. The genetic and physiological mechanisms underlying such remarkable adaptations remain poorly understood.Studies on small, wild-caught Passerines have unravelled several aspects of migratory physiology. However, they have not allowed to experimentally uncouple the suite of endogenous and environmental factors underlying the dynamics of the migratory state. I will circumvent such limitations by pioneering a novel experimental approach using two closely related, larger avian model species that are better suited for multi-scale investigations of proximate mechanisms and offer a direct comparison between migratory and sedentary individuals. The key goals of this post-doctoral project are to determine:(i) The physiological mechanisms associated with the activation and deactivation of the migratory state; (ii) Which genes modulate such transition via changes in their expression within key target organ tissues;(iii) Whether endocrine signals trigger the switching of the migratory state. This project will undertake a novel comparative and integrative approach to reveal completely new insights into the importance of understanding genetic and physiological pathways underlying the dynamics of the migratory state. It will also provide fruitful insights to both poultry science and biomedical research on the importance of nutrition on health and food safety. Ámbito científico natural sciencesbiological sciencesgeneticsnatural sciencesbiological scienceszoologyornithologynatural sciencesbiological sciencesevolutionary biologynatural sciencesbiological sciencesbiological behavioural sciencesbehavioural ecologynatural sciencesbiological sciencesbiological behavioural sciencesethology Programa(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Tema(s) MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Convocatoria de propuestas H2020-MSCA-IF-2015 Consulte otros proyectos de esta convocatoria Régimen de financiación MSCA-IF-EF-ST - Standard EF Coordinador VETERINAERMEDIZINISCHE UNIVERSITAET WIEN Aportación neta de la UEn € 166 156,80 Dirección Veterinaerplatz 1 1210 Wien Austria Ver en el mapa Región Ostösterreich Wien Wien Tipo de actividad Higher or Secondary Education Establishments Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 166 156,80