Objective
An emerging view of cortical area function posits that instead of primarily accounting for sensory processing and motor control, cortical areas might mediate flexible handling of sensory information and motor planning through learning and memory. In this project I propose to investigate this notion focusing on the function of retrosplenial cortex (RSC), a large, poorly understood and highly interconnected cortical area that interfaces with the hippocampal system. RSC has a key role in memory, and is thought to control flexible use of contextual information; it accounts for earliest memory deficits in Alzheimer’s disease.
In primates, the RSC is positioned immediately behind the splenium and is centrally located between cortical sensory and limbic memory regions. It exhibits reciprocal connections with the hippocampal for-mation, anterior thalamic nucleus, and a network of dorso-medial cortical areas. RSC has a critical role in spatial and relational memory, and its interactions with the hippocampal system are essential for normal memory processing.
The focus of this project is the hypothesis that the connectivity patterns of RSC account for what has been called its “translational” properties. I will first study the role of RSC in a generic form of flexible learning, then I will focus on spatial learning and analyse the capability of RSC to integrate information across multiple cue types and use these inputs to deal with the environment e.g. in allocentric-egocentric and egocen-tric-allocentric transformations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences zoology mammalogy primatology
- natural sciences biological sciences neurobiology
- medical and health sciences basic medicine neurology dementia alzheimer
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
4056 Basel
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.